Designing safer analgesics: a focus on μ-opioid receptor pathways

Cebranopadol, a novel first-in-class analgesic drug candidate

(2017) Annette Christoph et al.   PAIN

Measurement of Drug Liking in Abuse Potential Studies: A Comparison of Unipolar and Bipolar Visual Analog Scales

(2016) Beatrice Setnik et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Safety of buprenorphine transdermal system in the management of pain in older adults

(2016) Joseph V. Pergolizzi et al.   POSTGRADUATE MEDICINE

Cebranopadol: a first in-class example of a nociceptin/orphanin FQ receptor and opioid receptor agonist

(2015) D.G. Lambert et al.   BRITISH JOURNAL OF ANAESTHESIA

Buprenorphine infrequently found in fatal overdose in New York City

(2015) Denise Paone et al.   DRUG AND ALCOHOL DEPENDENCE

Tapentadol Abuse Potential: A Postmarketing Evaluation Using a Sample of Individuals Evaluated for Substance Abuse Treatment

(2015) Stephen F. Butler et al.   PAIN MEDICINE

Efficacy and tolerability of buccal buprenorphine in opioid-naive patients with moderate to severe chronic low back pain

(2015) Richard L. Rauck et al.   POSTGRADUATE MEDICINE

Tapentadol extended release in the management of peripheral diabetic neuropathic pain

(2015) Nalini Vadivelu et al.   Therapeutics and Clinical Risk Management

The clinical analgesic efficacy of buprenorphine

(2014) R. B. Raffa et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Combining Opioid and Adrenergic Mechanisms for Chronic Pain

(2014) Howard S. Smith et al.   POSTGRADUATE MEDICINE

Pilot the pulse: controlling the multiplicity of receptor dynamics

(2014) Andreas Bock et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Changing Face of Heroin Use in the United States

(2014) Theodore J. Cicero et al.   JAMA Psychiatry

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of the Extended-Release Tramadol Hydrochloride/Acetaminophen Fixed-Dose Combination Tablet for the Treatment of Chronic Low Back Pain

(2013) Jae Hyup Lee et al.   CLINICAL THERAPEUTICS

Extended-release tramadol/paracetamol in moderate-to-severe pain: a randomized, placebo-controlled study in patients with acute low back pain

(2012) Ben Lasko et al.   CURRENT MEDICAL RESEARCH AND OPINION

Mechanistic and functional differentiation of tapentadol and tramadol

(2012) Robert B Raffa et al.   EXPERT OPINION ON PHARMACOTHERAPY

Randomized, Double-Blind, Placebo-Controlled Study of the Abuse Potential of Different Formulations of Oral Oxycodone

(2012) Lynn R. Webster et al.   PAIN MEDICINE

Measuring online endorsement of prescription opioids abuse: an integrative methodology

(2012) Emily C. McNaughton et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Tapentadol in Pain Management

(2011) Craig T. Hartrick et al.   CNS DRUGS

Efficacy and Safety of Buprenorphine Transdermal System (BTDS) for Chronic Moderate to Severe Low Back Pain: A Randomized, Double-Blind Study

(2011) Deborah Steiner et al.   JOURNAL OF PAIN

Transdermal buprenorphine plus oral paracetamol vs an oral codeine-paracetamol combination for osteoarthritis of hip and/or knee: a randomised trial

(2011) P.G. Conaghan et al.   OSTEOARTHRITIS AND CARTILAGE

Tapentadol extended-release for treatment of chronic pain: a review

(2011) Nalini Vadivelu et al.   Journal of Pain Research

Current Knowledge of Buprenorphine and Its Unique Pharmacological Profile

(2010) Joseph Pergolizzi et al.   Pain Practice

Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine

(2009) Zhe Ding et al.   BRITISH JOURNAL OF PHARMACOLOGY

A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain

(2009) Stephen Daniels et al.   CURRENT MEDICAL RESEARCH AND OPINION

The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery

(2008) Jens-Ulrich Stegmann et al.   CURRENT MEDICAL RESEARCH AND OPINION

Basic pharmacology relevant to drug abuse assessment: tramadol as example

(2008) R. B. Raffa   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

(2008) David G. Lambert   NATURE REVIEWS DRUG DISCOVERY