New approaches to the design and discovery of therapies to prevent erectile dysfunction
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
New approaches to the design and discovery of therapies to prevent erectile dysfunction
Authors
Keywords
-
Journal
Expert Opinion on Drug Discovery
Volume 9, Issue 12, Pages 1447-1469
Publisher
Informa Healthcare
Online
2014-09-06
DOI
10.1517/17460441.2014.949234
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metabolic syndrome and erectile dysfunction among obese non-diabetic subjects
- (2014) A. Gatti et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Effect of Mesenchymal Stem Cells Associated to Matrixen on the Erectile Function in the Rat Model with Bilateral Cavernous Nerve Crushing Injury
- (2014) Su Jin Kim et al. International Braz J Urol
- Low-Intensity Shock Wave Therapy and Its Application to Erectile Dysfunction
- (2014) Hongen Lei et al. World Journal of Mens Health
- All Men with Vasculogenic Erectile Dysfunction Require a Cardiovascular Workup
- (2013) Martin Miner et al. AMERICAN JOURNAL OF MEDICINE
- The sGC activator BAY 60-2770 has potent erectile activity in the rat
- (2013) George F. Lasker et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Erectile function and late-onset hypogonadism symptoms related to lower urinary tract symptom severity in elderly men
- (2013) Ozan Bozkurt et al. ASIAN JOURNAL OF ANDROLOGY
- The response to testosterone undecanoate in men with type 2 diabetes is dependent on achieving threshold serum levels (the BLAST study)
- (2013) G. Hackett et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Evaluation of the Effect of Different Doses of Low Energy Shock Wave Therapy on the Erectile Function of Streptozotocin (STZ)-Induced Diabetic Rats
- (2013) Jing Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Orall-citrulline supplementation improves erectile function and penile structure in castrated rats
- (2013) Yuji Hotta et al. INTERNATIONAL JOURNAL OF UROLOGY
- Late-Onset Hypogonadism and Mortality in Aging Men
- (2013) S. R. Pye et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Distribution and Factors Associated with Four Premature Ejaculation Syndromes in Outpatients Complaining of Ejaculating Prematurely
- (2013) Xiansheng Zhang et al. Journal of Sexual Medicine
- Synergistic Effects of BAY 60‐4552 and Vardenafil on Relaxation of Corpus Cavernosum Tissue of Patients with Erectile Dysfunction and Clinical Phosphodiesterase Type 5 Inhibitor Failure
- (2013) Maarten Albersen et al. Journal of Sexual Medicine
- Testosterone Replacement Therapy with Long‒Acting Testosterone Undecanoate Improves Sexual Function and Quality‒of‒Life Parameters vs. Placebo in a Population of Men with Type 2 Diabetes
- (2013) Geoffrey Hackett et al. Journal of Sexual Medicine
- SOP Conservative (Medical and Mechanical) Treatment of Erectile Dysfunction
- (2013) Hartmut Porst et al. Journal of Sexual Medicine
- One Patient Out of Four with Newly Diagnosed Erectile Dysfunction Is a Young Man—Worrisome Picture from the Everyday Clinical Practice
- (2013) Paolo Capogrosso et al. Journal of Sexual Medicine
- Activated Rho Kinase Mediates Diabetes‐Induced Elevation of Vascular Arginase Activation and Contributes to Impaired Corpora Cavernosa Relaxation: Possible Involvement of p38 MAPK Activation
- (2013) Haroldo A. Toque et al. Journal of Sexual Medicine
- Sexual Activity and Aging
- (2013) Mary Ni Lochlainn et al. Journal of the American Medical Directors Association
- Akita Spontaneously Type 1 Diabetic Mice Exhibit Elevated Vascular Arginase and Impaired Vascular Endothelial and Nitrergic Function
- (2013) Haroldo A. Toque et al. PLoS One
- Correction of Diabetic Erectile Dysfunction with Adipose Derived Stem Cells Modified with the Vascular Endothelial Growth Factor Gene in a Rodent Diabetic Model
- (2013) Guihua Liu et al. PLoS One
- Oxidative stress in vascular disease and its pharmacological prevention
- (2013) Huige Li et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Combined Therapeutic Effect of Udenafil and Adipose-derived Stem Cell (ADSC)/Brain-derived Neurotrophic Factor (BDNF)–Membrane System in a Rat Model of Cavernous Nerve Injury
- (2013) Ho Hun Jeong et al. UROLOGY
- Sildenafil increases serum testosterone levels by a direct action on the testes
- (2013) M. Spitzer et al. Andrology
- Arginase 1 Mediates Increased Blood Pressure and Contributes to Vascular Endothelial Dysfunction in Deoxycorticosterone Acetate-Salt Hypertension
- (2013) Haroldo A. Toque et al. Frontiers in Immunology
- Extracorporeal shock waves improve angiogenesis after full thickness burn
- (2012) O. Goertz et al. BURNS
- Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout
- (2012) Lin Yao et al. CARDIOVASCULAR RESEARCH
- The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes
- (2012) S. C. Elms et al. DIABETOLOGIA
- Chronic Oral Administration of the Arginase Inhibitor 2(S)-amino-6-boronohexanoic Acid (ABH) Improves Erectile Function in Aged Rats
- (2012) R. Segal et al. JOURNAL OF ANDROLOGY
- Testosterone Deficiency in Men: Systematic Review and Standard Operating Procedures for Diagnosis and Treatment
- (2012) Jacques Buvat et al. Journal of Sexual Medicine
- Does Low Intensity Extracorporeal Shock Wave Therapy Have a Physiological Effect on Erectile Function? Short-Term Results of a Randomized, Double-Blind, Sham Controlled Study
- (2012) Yoram Vardi et al. JOURNAL OF UROLOGY
- Erectile dysfunction
- (2012) Rany Shamloul et al. LANCET
- Emerging tools for erectile dysfunction: a role for regenerative medicine
- (2012) Lukman Hakim et al. Nature Reviews Urology
- Chronicl-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats
- (2012) Md. Ashraful Alam et al. Food & Function
- Influence of age and changes over time on erectile dysfunction: Results from two large cross-sectional surveys 11 years apart
- (2012) Johan Stranne et al. Scandinavian Journal of Urology
- Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway
- (2011) Alia Shatanawi et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Testosterone regulates smooth muscle contractile pathways in the rat prostate: emphasis on PDE5 signaling
- (2011) Xinhua Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Diabetes-induced vascular dysfunction involves arginase I
- (2011) Maritza J. Romero et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases
- (2011) Tohru Fukai et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway
- (2011) S Chandra et al. BRITISH JOURNAL OF PHARMACOLOGY
- Tadalafil once daily and extracorporeal shock wave therapy in the management of patients with Peyronie’s disease and erectile dysfunction: results from a prospective randomized trial
- (2011) A. Palmieri et al. INTERNATIONAL JOURNAL OF ANDROLOGY
- Combined Strategy of Mesenchymal Stem Cell Injection With Vascular Endothelial Growth Factor Gene Therapy for the Treatment of Diabetes-Associated Erectile Dysfunction
- (2011) X. Qiu et al. JOURNAL OF ANDROLOGY
- Extracellular Signal‐Regulated Kinase (ERK) Inhibition Decreases Arginase Activity and Improves Corpora Cavernosal Relaxation in Streptozotocin (STZ)‐Induced Diabetic Mice
- (2011) Kenia P. Nunes et al. Journal of Sexual Medicine
- Erectile Dysfunction, Depression, and Ischemic Heart Disease: Does the Existence of One Component of This Triad Necessitate Inquiring the Other Two? (CME)
- (2011) Ahmed I El‐Sakka Journal of Sexual Medicine
- State-of-the-art gene-based therapies: the road ahead
- (2011) Mark A. Kay NATURE REVIEWS GENETICS
- Oral L-Citrulline Supplementation Improves Erection Hardness in Men With Mild Erectile Dysfunction
- (2011) Luigi Cormio et al. UROLOGY
- Effect of mesenchymal stem cell penile transplantation on erectile signaling of aged rats
- (2010) M. T. Abdel Aziz et al. ANDROLOGIA
- Long-term oral treatment with BAY 41-2272 ameliorates impaired corpus cavernosum relaxations in a nitric oxide-deficient rat model
- (2010) Mário A. Claudino et al. BJU INTERNATIONAL
- Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension
- (2010) Teddy Bagnost et al. CARDIOVASCULAR RESEARCH
- Can Low-Intensity Extracorporeal Shockwave Therapy Improve Erectile Function? A 6-Month Follow-up Pilot Study in Patients with Organic Erectile Dysfunction
- (2010) Yoram Vardi et al. EUROPEAN UROLOGY
- Guidelines on Male Sexual Dysfunction: Erectile Dysfunction and Premature Ejaculation
- (2010) Konstantinos Hatzimouratidis et al. EUROPEAN UROLOGY
- p38 Mitogen-Activated Protein Kinase (MAPK) Increases Arginase Activity and Contributes to Endothelial Dysfunction in Corpora Cavernosa from Angiotensin-II-Treated Mice
- (2010) Haroldo A. Toque et al. Journal of Sexual Medicine
- ORIGINAL ARTICLES: Definitions/Epidemiology/Risk Factors for Sexual Dysfunction
- (2010) Ronald W. Lewis et al. Journal of Sexual Medicine
- Summary of the Recommendations on Sexual Dysfunctions in Men
- (2010) Francesco Montorsi et al. Journal of Sexual Medicine
- Arginase II Deletion Increases Corpora Cavernosa Relaxation in Diabetic Mice
- (2010) Haroldo A. Toque et al. Journal of Sexual Medicine
- Evaluation and Treatment of Erectile Dysfunction
- (2010) Maarten Albersen et al. MEDICAL CLINICS OF NORTH AMERICA
- Recent advances in arginine metabolism: roles and regulation of the arginases
- (2009) Sidney M Morris Jr BRITISH JOURNAL OF PHARMACOLOGY
- Rho Kinase: An Important Mediator of Atherosclerosis and Vascular Disease
- (2009) Qian Zhou et al. CURRENT PHARMACEUTICAL DESIGN
- Comparison of long-acting testosterone undecanoate formulation versus testosterone enanthate on sexual function and mood in hypogonadal men
- (2009) F Jockenhövel et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis
- (2009) K Park et al. INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
- Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats
- (2009) Jae Hyung Kim et al. JOURNAL OF APPLIED PHYSIOLOGY
- Extracorporeal shock wave lithotripsy of large difficult common bile duct stones: Efficacy and analysis of factors that favor stone fragmentation
- (2009) Manu Tandan et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Testosterone Partially Ameliorates Metabolic Profile and Erectile Responsiveness to PDE5 Inhibitors in an Animal Model of Male Metabolic Syndrome
- (2009) Sandra Filippi et al. Journal of Sexual Medicine
- Type 1 and Type 2 Diabetic‐Erectile Dysfunction: Same Diagnosis (ICD‐9), Different Disease?
- (2009) Kanchan Chitaley Journal of Sexual Medicine
- Fibroblast Growth Factor 2 Promotes Endothelial Differentiation of Adipose Tissue-Derived Stem Cells
- (2009) Hongxiu Ning et al. Journal of Sexual Medicine
- Treatment of Erectile Dysfunction in the Obese Type 2 Diabetic ZDF Rat with Adipose Tissue-Derived Stem Cells
- (2009) Maurice M. Garcia et al. Journal of Sexual Medicine
- The role of testosterone in erectile dysfunction
- (2009) Giovanni Corona et al. Nature Reviews Urology
- Emerging neuromodulatory molecules for the treatment of neurogenic erectile dysfunction caused by cavernous nerve injury
- (2008) Anthony J. Bella et al. ASIAN JOURNAL OF ANDROLOGY
- VEGF improves survival of mesenchymal stem cells in infarcted hearts
- (2008) Jennifer Pons et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- DOCA-salt treatment enhances responses to endothelin-1 in murine corpus cavernosumThis article is one of a selection of papers published in the special issue (part 1 of 2) on Forefronts in Endothelin.
- (2008) Fernando S. Carneiro et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- A review of current progress in gene and stem cell therapy for erectile dysfunction
- (2008) Serap Gur et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Stem and endothelial progenitor cells in erection biology
- (2008) T D Strong et al. INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
- Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction
- (2008) Hitoshi Masuda INTERNATIONAL JOURNAL OF UROLOGY
- Dietary l-Arginine Supplementation Reduces White Fat Gain and Enhances Skeletal Muscle and Brown Fat Masses in Diet-Induced Obese Rats
- (2008) Wenjuan Jobgen et al. JOURNAL OF NUTRITION
- Laboratory Forum: Cavernous Nerve Injury Using Rodent Animal Models
- (2008) Onder Canguven et al. Journal of Sexual Medicine
- Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism
- (2007) Edzard Schwedhelm et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity
- (2007) Maritza J. Romero et al. CIRCULATION RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More