Anxiolytic drug discovery: what are the novel approaches and how can we improve them?
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Anxiolytic drug discovery: what are the novel approaches and how can we improve them?
Authors
Keywords
-
Journal
Expert Opinion on Drug Discovery
Volume 9, Issue 1, Pages 15-26
Publisher
Informa Healthcare
Online
2013-11-09
DOI
10.1517/17460441.2014.857309
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Peripheral oxytocin administration buffers autonomic but not behavioral responses to environmental stressors in isolated prairie voles
- (2016) Angela J. Grippo et al. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
- Perspectives on Zebrafish Models of Hallucinogenic Drugs and Related Psychotropic Compounds
- (2013) Nikhil Neelkantan et al. ACS Chemical Neuroscience
- Synaptic Mechanisms Underlying Rapid Antidepressant Action of Ketamine
- (2013) Ege T. Kavalali et al. AMERICAN JOURNAL OF PSYCHIATRY
- Developing ‘integrative’ zebrafish models of behavioral and metabolic disorders
- (2013) Michael Nguyen et al. BEHAVIOURAL BRAIN RESEARCH
- Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment
- (2013) Ryan Y Wong et al. BMC GENOMICS
- Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations
- (2013) Olga A. Wudarczyk et al. CURRENT OPINION IN PSYCHIATRY
- Emergence of anxiety-like behaviours in depressive-like Cpefat/fat mice
- (2013) Ramona M. Rodriguiz et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- A brief history of oxytocin and its role in modulating psychostimulant effects
- (2013) Dean S Carson et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Effects of Schedule I drug laws on neuroscience research and treatment innovation
- (2013) David J. Nutt et al. NATURE REVIEWS NEUROSCIENCE
- Perspectives on experimental models of serotonin syndrome in zebrafish
- (2013) Adam Michael Stewart et al. NEUROCHEMISTRY INTERNATIONAL
- CRF–CRF1 Receptor System in the Central and Basolateral Nuclei of the Amygdala Differentially Mediates Excessive Eating of Palatable Food
- (2013) Attilio Iemolo et al. NEUROPSYCHOPHARMACOLOGY
- Perinatal high fat diet alters glucocorticoid signaling and anxiety behavior in adulthood
- (2013) A. Sasaki et al. NEUROSCIENCE
- Obesity and psychiatric disorders: Commonalities in dysregulated biological pathways and their implications for treatment
- (2013) Adrian L. Lopresti et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Deep brain stimulation affects conditioned and unconditioned anxiety in different brain areas
- (2013) A van Dijk et al. Translational Psychiatry
- Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders
- (2013) K. MacDonald et al. Frontiers in Neuroscience
- Animal Models of Serotonergic Psychedelics
- (2012) James B. Hanks et al. ACS Chemical Neuroscience
- Antidepressant‐like effects of ecstasy in subjects with a predisposition to depression
- (2012) Irina Majumder et al. ADDICTIVE BEHAVIORS
- Unique and potent effects of acute ibogaine on zebrafish: The developing utility of novel aquatic models for hallucinogenic drug research
- (2012) Jonathan Cachat et al. BEHAVIOURAL BRAIN RESEARCH
- Constructing the habituome for phenotype-driven zebrafish research
- (2012) Adam Michael Stewart et al. BEHAVIOURAL BRAIN RESEARCH
- Oxytocin: a therapeutic target for mental disorders
- (2012) Mitsuhiro Matsuzaki et al. Journal of Physiological Sciences
- Neuroendocrine control of feeding behavior and psychomotor activity by neuropeptideY in fish
- (2012) Kouhei Matsuda et al. NEUROPEPTIDES
- Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders
- (2012) Marianna Stamou et al. NEUROTOXICOLOGY AND TERATOLOGY
- Longitudinal Association Between Marital Disruption and Child BMI and Obesity
- (2012) Jeremy Arkes Obesity
- Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology
- (2012) Evan J. Kyzar et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Longitudinal Relationship of Depressive and Anxiety Symptoms With Dyslipidemia and Abdominal Obesity
- (2012) Arianne K.B. van Reedt Dortland et al. PSYCHOSOMATIC MEDICINE
- Autism and autistic spectrum disorders in the context of new DSM-V classification, and clinical and epidemiological data
- (2012) Miodrag Stankovic et al. Srpski Arhiv za Celokupno Lekarstvo
- Inhibition of immobilization stress-induced anorexia, behavioral deficits, and plasma corticosterone secretion by injected leptin in rats
- (2012) Zeba Haque et al. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
- Expanding applications of deep brain stimulation: a potential therapeutic role in obesity and addiction management
- (2011) Casey H. Halpern et al. ACTA NEUROCHIRURGICA
- Zebrafish in Endocrine Systems: Recent Advances and Implications for Human Disease
- (2011) Heiko Löhr et al. Annual Review of Physiology
- Behavioral performance altering effects of MK-801 in zebrafish (Danio rerio)
- (2011) Margarette Sison et al. BEHAVIOURAL BRAIN RESEARCH
- Behavioral effects of MDMA (‘ecstasy’) on adult zebrafish
- (2011) Adam Stewart et al. BEHAVIOURAL PHARMACOLOGY
- Serotonergic and Noradrenergic Pathways Are Required for the Anxiolytic-like and Antidepressant-like Behavioral Effects of Repeated Vagal Nerve Stimulation in Rats
- (2011) Havan Furmaga et al. BIOLOGICAL PSYCHIATRY
- Fish melanocortin system
- (2011) José Miguel Cerdá-Reverter et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models
- (2011) M. Li et al. Experimental Diabetes Research
- Experimental models for anxiolytic drug discovery in the era ofomesandomics
- (2011) Adam Stewart et al. Expert Opinion on Drug Discovery
- Prosocial effects of oxytocin and clinical evidence for its therapeutic potential
- (2011) Nadine Striepens et al. FRONTIERS IN NEUROENDOCRINOLOGY
- The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies
- (2011) Meera E. Modi et al. HORMONES AND BEHAVIOR
- Behavioral and physiological effects of acute ketamine exposure in adult zebrafish
- (2011) Russell Riehl et al. NEUROTOXICOLOGY AND TERATOLOGY
- Stimulatory effect of intracerebroventricular administration of orexin A on food intake in the zebrafish, Danio rerio
- (2011) Eri Yokobori et al. PEPTIDES
- Identification of a brain center whose activity discriminates a choice behavior in zebrafish
- (2011) B. Y. B. Lau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of behavioral and endocrine effects of LSD on zebrafish
- (2010) Leah Grossman et al. BEHAVIOURAL BRAIN RESEARCH
- Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish
- (2010) S.K. Richetti et al. BEHAVIOURAL BRAIN RESEARCH
- Cognitive bias in the chick anxiety–depression model
- (2010) Amy L. Salmeto et al. BRAIN RESEARCH
- Ghrelin affects carbohydrate-glycogen metabolism via insulin inhibition and glucagon stimulation in the zebrafish (Danio rerio) brain
- (2010) Shelly A. Cruz et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
- Lack of the serotonin transporter in mice reduces locomotor activity and leads to gender-dependent late onset obesity
- (2010) N Üçeyler et al. INTERNATIONAL JOURNAL OF OBESITY
- Identification of the Zebrafish Ventral Habenula As a Homolog of the Mammalian Lateral Habenula
- (2010) R. Amo et al. JOURNAL OF NEUROSCIENCE
- The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study
- (2010) Michael C Mithoefer et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models
- (2010) B M Andrus et al. MOLECULAR PSYCHIATRY
- Measuring behavioral and endocrine responses to novelty stress in adult zebrafish
- (2010) Jonathan Cachat et al. Nature Protocols
- The comparative neuroanatomy and neurochemistry of zebrafish CNS systems of relevance to human neuropsychiatric diseases
- (2010) P. Panula et al. NEUROBIOLOGY OF DISEASE
- Low stress reactivity and neuroendocrine factors in the BTBR T+tf/J mouse model of autism
- (2010) J.L. Silverman et al. NEUROSCIENCE
- Scopolamine-induced learning impairment reversed by physostigmine in zebrafish
- (2010) Yeon-Hwa Kim et al. NEUROSCIENCE RESEARCH
- Psychedelics and the Human Receptorome
- (2010) Thomas S. Ray PLoS One
- Pharmacological modulation of anxiety-like phenotypes in adult zebrafish behavioral models
- (2010) Adam Stewart et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- A behavioral and molecular analysis of ketamine in zebrafish
- (2010) Sherry M. Zakhary et al. SYNAPSE
- The Peptide That Binds
- (2010) Kai MacDonald et al. HARVARD REVIEW OF PSYCHIATRY
- Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish
- (2009) Rupert J. Egan et al. BEHAVIOURAL BRAIN RESEARCH
- Refining psychiatric genetics: from ‘mouse psychiatry’ to understanding complex human disorders
- (2009) Justin L. LaPorte et al. BEHAVIOURAL PHARMACOLOGY
- Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression
- (2009) Bettina H. Bewernick et al. BIOLOGICAL PSYCHIATRY
- Zebrafish: A Complete Animal Model for In Vivo Drug Discovery and Development
- (2009) Chiranjib Chakraborty et al. CURRENT DRUG METABOLISM
- Qui non proficit, deficit: Experimental models for ‘integrative’ research of affective disorders
- (2009) Justin L. LaPorte et al. JOURNAL OF AFFECTIVE DISORDERS
- Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution
- (2009) Marnix Gorissen et al. JOURNAL OF ENDOCRINOLOGY
- Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats
- (2009) D.A. Slattery et al. NEUROPHARMACOLOGY
- Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
- (2009) Robert H. Ring et al. NEUROPHARMACOLOGY
- Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP
- (2009) Jill L Silverman et al. NEUROPSYCHOPHARMACOLOGY
- Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation
- (2009) Angela J. Grippo et al. PSYCHONEUROENDOCRINOLOGY
- A pilot study of vagus nerve stimulation (VNS) for treatment-resistant anxiety disorders
- (2008) Mark S. George et al. Brain Stimulation
- Modelling the anxiety-depression continuum in chicks
- (2008) JE Warnick et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease
- (2008) Alim Louis Benabid et al. LANCET NEUROLOGY
- Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders
- (2008) S Kim et al. MOLECULAR PSYCHIATRY
- Serotonin research: contributions to understanding psychoses
- (2008) M GEYER et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Development of the corticosteroid stress axis and receptor expression in zebrafish
- (2007) Derek Alsop et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Domain interplay concept in animal models of neuropsychiatric disorders: A new strategy for high-throughput neurophenotyping research
- (2007) A KALUEFF BEHAVIOURAL BRAIN RESEARCH
- The behavioral pharmacology of hallucinogens
- (2007) William E. Fantegrossi et al. BIOCHEMICAL PHARMACOLOGY
- Functional and developmental analysis of the blood–brain barrier in zebrafish
- (2007) Jae-Yeon Jeong et al. BRAIN RESEARCH BULLETIN
- Striatal dopamine D2 receptor availability in OCD with and without comorbid social anxiety disorder: preliminary findings
- (2007) Franklin R. Schneier et al. DEPRESSION AND ANXIETY
- A randomized, double-blind clinical trial on the efficacy of cortical direct current stimulation for the treatment of major depression
- (2007) Paulo S. Boggio et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Deep brain stimulation in 18 patients with severe Gilles de la Tourette syndrome refractory to treatment: the surgery and stimulation
- (2007) D Servello et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search