Glutamate drugs and pharmacogenetics of OCD: a pathway-based exploratory approach

The Effect of Riluzole Augmentation in a Patient With Treatment-Resistant Obsessive-Compulsive Disorder, Taking Two Other Glutaminergic Agents

(2014) Nahla Mahgoub et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action

(2014) Olivia Dean et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Decoding the SUMO signal

(2013) Ronald T. Hay   BIOCHEMICAL SOCIETY TRANSACTIONS

The SLC1 high-affinity glutamate and neutral amino acid transporter family

(2013) Yoshikatsu Kanai et al.   MOLECULAR ASPECTS OF MEDICINE

The promise of N-acetylcysteine in neuropsychiatry

(2013) Michael Berk et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Attention System of the Human Brain: 20 Years After

(2012) Steven E. Petersen et al.   Annual Review of Neuroscience

Calcium leak through ryanodine receptor is involved in neuronal death induced by mutant huntingtin

(2012) Mari Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of the glutamate transporter EAAT3 by mammalian target of rapamycin mTOR

(2012) Ahmad Almilaji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of Ketamine in Treatment-Refractory Obsessive-Compulsive Disorder

(2012) Michael H. Bloch et al.   BIOLOGICAL PSYCHIATRY

Role of Leaky Neuronal Ryanodine Receptors in Stress- Induced Cognitive Dysfunction

(2012) Xiaoping Liu et al.   CELL

Cholesterol loss during glutamate-mediated excitotoxicity

(2012) Alejandro O Sodero et al.   EMBO JOURNAL

PCB-95 Promotes Dendritic Growth via Ryanodine Receptor–Dependent Mechanisms

(2012) Gary A. Wayman et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

(2012) Ankita Mehta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Treatment with Adjunctive N-Acetylcysteine in an Adolescent with Selective Serotonin Reuptake Inhibitor-Resistant Anxiety

(2012) Jeffrey R. Strawn et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

N-Acetylcysteine Add-On Treatment in Refractory Obsessive-Compulsive Disorder

(2012) Hamid Afshar et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

The Density of EAAC1 (EAAT3) Glutamate Transporters Expressed by Neurons in the Mammalian CNS

(2012) S. Holmseth et al.   JOURNAL OF NEUROSCIENCE

N-Acetyl-L-Cysteine Inhibits Marble-Burying Behavior in Mice

(2012) Nobuaki Egashira et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Memantine add-on in moderate to severe obsessive-compulsive disorder: Randomized double-blind placebo-controlled study

(2012) Ali Ghaleiha et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Adar is essential for optimal presynaptic function

(2012) Carolina Maldonado et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Structure and mechanism of a glutamate–GABA antiporter

(2012) Dan Ma et al.   NATURE

Synaptic scaffold evolution generated components of vertebrate cognitive complexity

(2012) Jess Nithianantharajah et al.   NATURE NEUROSCIENCE

Targeting metabotropic glutamate receptors in neuroimmune communication

(2012) C. Volpi et al.   NEUROPHARMACOLOGY

Activity-regulated RNA editing in select neuronal subfields in hippocampus

(2012) Ales Balik et al.   NUCLEIC ACIDS RESEARCH

N-acetylcysteine Protects against Apoptosis through Modulation of Group I Metabotropic Glutamate Receptor Activity

(2012) Lili Sun et al.   PLoS One

Twenty-five Years of Glutamate in Schizophrenia: Are We There Yet?

(2012) D. C. Javitt   SCHIZOPHRENIA BULLETIN

mTOR: on target for novel therapeutic strategies in the nervous system

(2012) Kenneth Maiese et al.   TRENDS IN MOLECULAR MEDICINE

NMDA Receptor-Dependent Long-Term Potentiation and Long-Term Depression (LTP/LTD)

(2012) C. Luscher et al.   Cold Spring Harbor Perspectives in Biology

N-acetylcysteine augmentation in treatment resistant obsessive compulsive disorder: A case series

(2012) Michael Van Ameringen et al.   Journal of Obsessive-Compulsive and Related Disorders

Homeobox genes in obsessive-compulsive disorder

(2011) G. Nestadt et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Modulation of neuronal glutathione synthesis by EAAC1 and its interacting protein GTRAP3-18

(2011) Koji Aoyama et al.   AMINO ACIDS

Intravenous Ketamine for Treatment-Resistant Major Depressive Disorder

(2011) Jordan R Covvey et al.   ANNALS OF PHARMACOTHERAPY

mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration.

(2011) Richard M. Cleva et al.   BEHAVIORAL NEUROSCIENCE

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

The Effect of N-Acetylcysteine in the Nucleus Accumbens on Neurotransmission and Relapse to Cocaine

(2011) Yonatan M. Kupchik et al.   BIOLOGICAL PSYCHIATRY

Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients

(2011) Monia Raffa et al.   BMC Psychiatry

Ketamine as a Novel Antidepressant: From Synapse to Behavior

(2011) J W Murrough   CLINICAL PHARMACOLOGY & THERAPEUTICS

Glutamate Binding-Site Ligands of NMDA Receptors

(2011) C. Bonaccorso et al.   CURRENT MEDICINAL CHEMISTRY

Neurobiology of obsessive–compulsive disorder: insights into neural circuitry dysfunction through mouse genetics

(2011) Jonathan T Ting et al.   CURRENT OPINION IN NEUROBIOLOGY

Investigational NMDA receptor modulators for depression

(2011) Bernadeta Szewczyk et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Genomewide linkage analysis in Costa Rican families implicates chromosome 15q14 as a candidate region for OCD

(2011) Jessica Ross et al.   HUMAN GENETICS

Rapid Resolution of Obsessions After an Infusion of Intravenous Ketamine in a Patient With Treatment-Resistant Obsessive-Compulsive Disorder

(2011) Carolyn I. Rodriguez et al.   JOURNAL OF CLINICAL PSYCHIATRY

The Genetics of Obsessive-Compulsive Disorder and Tourette Syndrome: An Epidemiological and Pathway-Based Approach for Gene Discovery

(2011) Marco A. Grados   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Activity Regulation of Adenosine Deaminases Acting on RNA (ADARs)

(2011) Cesare Orlandi et al.   MOLECULAR NEUROBIOLOGY

Positive Allosteric Modulators of Type 5 Metabotropic Glutamate Receptors (mGluR5) and Their Therapeutic Potential for the Treatment of CNS Disorders

(2011) Richard M. Cleva et al.   MOLECULES

Glutamate abnormalities in obsessive compulsive disorder: Neurobiology, pathophysiology, and treatment

(2011) Christopher Pittenger et al.   PHARMACOLOGY & THERAPEUTICS

The role of glutamate signaling in the pathogenesis and treatment of obsessive–compulsive disorder

(2011) Ke Wu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways

(2011) Mohammed R. Milad et al.   TRENDS IN COGNITIVE SCIENCES

Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

(2010) Shau-Kwaun Chen et al.   CELL

Potential Psychiatric Applications of Metabotropic Glutamate Receptor Agonists and Antagonists

(2010) John H. Krystal et al.   CNS DRUGS

A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

(2010) Mark C. Bellingham   CNS Neuroscience & Therapeutics

Acamprosate: How, Where, and for Whom Does it Work? Mechanism of Action, Treatment Targets, and Individualized Therapy

(2010) Falk Kiefer et al.   CURRENT PHARMACEUTICAL DESIGN

Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction

(2010) Khaled Moussawi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Acamprosate

(2010) William Klugh Kennedy et al.   Expert Opinion on Drug Metabolism & Toxicology

A Single-Blinded Case-Control Study of Memantine in Severe Obsessive-Compulsive Disorder

(2010) S. Evelyn Stewart et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice

(2010) I. Goussakov et al.   JOURNAL OF NEUROSCIENCE

Glutamate joins the ranks of immunomodulators

(2010) Anna M Hansen et al.   NATURE MEDICINE

Relationship of Possible Stress-Related Biochemical Markers to Oxidative/Antioxidative Status in Obsessive-Compulsive Disorder

(2010) A. Behl et al.   NEUROPSYCHOBIOLOGY

Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

(2010) Tao Ma et al.   PLoS One

Glycine and glycine receptor signaling in hippocampal neurons: Diversity, function and regulation

(2010) Tian-Le Xu et al.   PROGRESS IN NEUROBIOLOGY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

High-Dose Glycine Treatment of Refractory Obsessive-Compulsive Disorder and Body Dysmorphic Disorder in a 5-Year Period

(2010) W. Louis Cleveland et al.   NEURAL PLASTICITY

A family-based association study of the glutamate transporter geneSLC1A1in obsessive-compulsive disorder in 378 families

(2009) Y.Y. Shugart et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

N-Acetylcysteine, a Glutamate Modulator, in the Treatment of Trichotillomania

(2009) Jon E. Grant et al.   ARCHIVES OF GENERAL PSYCHIATRY

Adverse reactions associated with acetylcysteine

(2009) E.A. Sandilands et al.   CLINICAL TOXICOLOGY

Memantine Augmentation in Treatment-Resistant Obsessive-Compulsive Disorder

(2009) Elias Aboujaoude et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Glycine as a neurotransmitter in the forebrain: a short review

(2009) Marina Sorrentino Hernandes et al.   JOURNAL OF NEURAL TRANSMISSION

The involvement of the NMDA receptor d-serine/glycine site in the pathophysiology and treatment of schizophrenia

(2009) Viviane Labrie et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive–compulsive disorder

(2009) Paul Daniel Arnold et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

The way of our errors: Theme and variations

(2009) Robert F. Simons   PSYCHOPHYSIOLOGY

Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding

(2008) Kung-Yee Liang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Critical Parameters ford-Cycloserine Enhancement of Cognitive-Behaviorial Therapy for Obsessive-Compulsive Disorder

(2008) Barbara Olasov Rothbaum   AMERICAN JOURNAL OF PSYCHIATRY

Augmentation of Behavior Therapy Withd-Cycloserine for Obsessive-Compulsive Disorder

(2008) Sabine Wilhelm et al.   AMERICAN JOURNAL OF PSYCHIATRY

Riluzole in psychiatry: a systematic review of the literature

(2008) Carlos A Zarate et al.   Expert Opinion on Drug Metabolism & Toxicology

Adjunctive glycine in the treatment of obsessive-compulsive disorder in adults

(2008) William M. Greenberg et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Topiramate: Its Pharmacological Properties and Therapeutic Efficacy in Epilepsy

(2008) Giuseppe Latini et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Glutathione: Overview of its protective roles, measurement, and biosynthesis

(2008) Henry Jay Forman et al.   MOLECULAR ASPECTS OF MEDICINE

The orbitofrontal cortex and beyond: From affect to decision-making

(2008) Edmund T. Rolls et al.   PROGRESS IN NEUROBIOLOGY

Quality of life in obsessive-compulsive disorder: an evaluation of impairment and a preliminary analysis of the ameliorating effects of treatment

(2007) Melissa M. Norberg et al.   DEPRESSION AND ANXIETY