Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges

Multifunctional Iron Oxide Nanoparticles for Diagnostics, Therapy and Macromolecule Delivery

(2014) Swee Kuan Yen et al.   Theranostics

Selective Targeting Capability Acquired with a Protein Corona Adsorbed on the Surface of 1,2-Dioleoyl-3-trimethylammonium Propane/DNA Nanoparticles

(2013) Giulio Caracciolo et al.   ACS Applied Materials & Interfaces

Optimizing the Properties of the Protein Corona Surrounding Nanoparticles for Tuning Payload Release

(2013) Anna Cifuentes-Rius et al.   ACS Nano

Exocytosis of nanoparticles from cells: Role in cellular retention and toxicity

(2013) Ramin Sakhtianchi et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

In vivo hepatocyte MR imaging using lactose functionalized magnetoliposomes

(2013) Ashwini Ketkar-Atre et al.   BIOMATERIALS

Protein corona significantly reduces active targeting yield

(2013) Vahid Mirshafiee et al.   CHEMICAL COMMUNICATIONS

Nanocapsules with specific targeting and release properties using miniemulsion polymerization

(2013) Katharina Landfester et al.   Expert Opinion on Drug Delivery

Targeted therapy for human hepatic carcinoma cells using folate-functionalized polymeric micelles loaded with superparamagnetic iron oxide and sorafenib in vitro

(2013) Lei Zhang et al.   International Journal of Nanomedicine

Intra-operativeex vivophotoacoustic nodal staging in a rat model using a clinical superparamagnetic iron oxide nanoparticle dispersion

(2013) Diederik J. Grootendorst et al.   Journal of Biophotonics

PEGylation of SPIONs by polycondensation reactions: a new strategy to improve colloidal stability in biological media

(2013) Wesley Renato Viali et al.   JOURNAL OF NANOPARTICLE RESEARCH

Variation of Protein Corona Composition of Gold Nanoparticles Following Plasmonic Heating

(2013) Morteza Mahmoudi et al.   NANO LETTERS

Protein corona affects the relaxivity and MRI contrast efficiency of magnetic nanoparticles

(2013) Houshang Amiri et al.   Nanoscale

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

An RGD-Modified MRI-Visible Polymeric Vector for Targeted siRNA Delivery to Hepatocellular Carcinoma in Nude Mice

(2013) Chun Wu et al.   PLoS One

Difference between Toxicities of Iron Oxide Magnetic Nanoparticles with Various Surface-Functional Groups against Human Normal Fibroblasts and Fibrosarcoma Cells

(2013) Won Yang et al.   Materials

Superparamagnetic iron oxide nanoparticles alter expression of obesity and T2D-associated risk genes in human adipocytes

(2013) S. Sharifi et al.   Scientific Reports

Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy

(2013) Gang Huang et al.   Theranostics

Adsorption of a Protein Monolayer via Hydrophobic Interactions Prevents Nanoparticle Aggregation under Harsh Environmental Conditions

(2013) Sergio Dominguez-Medina et al.   ACS Sustainable Chemistry & Engineering

Preventing Protein Adsorption and Macrophage Uptake of Gold Nanoparticles via a Hydrophobic Shield

(2012) Timothy A. Larson et al.   ACS Nano

Exploiting the Protein Corona around Gold Nanorods for Loading and Triggered Release

(2012) James Chen Yong Kah et al.   ACS Nano

Targeting of Primary Breast Cancers and Metastases in a Transgenic Mouse Model Using Rationally Designed Multifunctional SPIONs

(2012) Forrest M. Kievit et al.   ACS Nano

Development of Multifunctional Hyaluronan-Coated Nanoparticles for Imaging and Drug Delivery to Cancer Cells

(2012) Mohammad H. El-Dakdouki et al.   BIOMACROMOLECULES

Rotavirus capsid surface protein VP4-coated Fe3O4 nanoparticles as a theranostic platform for cellular imaging and drug delivery

(2012) Weihong Chen et al.   BIOMATERIALS

Superparamagnetic iron oxide and drug complex-embedded acoustic droplets for ultrasound targeted theranosis

(2012) Chung-Hsin Wang et al.   BIOMATERIALS

Dextran stabilized iron oxide nanoparticles: Synthesis, characterization and in vitro studies

(2012) Sheeja Liza Easo et al.   CARBOHYDRATE POLYMERS

Efficient γ-amino-proline-derived cell penetrating peptide–superparamagnetic iron oxide nanoparticle conjugates via aniline-catalyzed oxime chemistry as bimodal imaging nanoagents

(2012) Silvia Cavalli et al.   CHEMICAL COMMUNICATIONS

Synthesis of β-cyclodextrin conjugated superparamagnetic iron oxide nanoparticles for selective binding and detection of cholesterol crystals

(2012) Hongguang Li et al.   CHEMICAL COMMUNICATIONS

Therapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Diseases with Compromise to the Blood Brain Barrier

(2012) Silke Krol et al.   CHEMICAL REVIEWS

On designing stable magnetic vectors as carriers for malaria DNA vaccine

(2012) Fatin Nawwab Al-Deen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Magnetically Vectored Delivery of Cancer Drug Using Remotely On–Off Switchable NanoCapsules

(2012) Seong Deok Kong et al.   IEEE TRANSACTIONS ON MAGNETICS

Size-controlled synthesis of superparamagnetic iron oxide nanoparticles and their surface coating by gold for biomedical applications

(2012) H. Maleki et al.   JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

Effects of PEG Length and Iron Oxide Nanoparticles Size on Reduced Protein Adsorption and Non-Specific Uptake by Macrophage Cells

(2012) Fang Ni et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Efficient Internalization of Peptide-Conjugated SPIONs in Dendritic Cells for Tumor Targeting

(2012) Do Kyung Kim et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Erratum

(2012)   Nanomedicine

Interview: An architectural journey: from trees, dendrons/dendrimers to nanomedicine

(2012) Donald A Tomalia   Nanomedicine

Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors

(2012) Esben Kjær Unmack Larsen et al.   Nanoscale

Preparation andin vitroevaluation of folate-receptor-targeted SPION–polymer micelle hybrids for MRI contrast enhancement in cancer imaging

(2012) Shveta Mahajan et al.   NANOTECHNOLOGY

Conjugation of Functionalized SPIONs with Transferrin for Targeting and Imaging Brain Glial Tumors in Rat Model

(2012) Weili Jiang et al.   PLoS One

Electrochemical biosensors for glucose based on metal nanoparticles

(2012) Amir Ata Saei et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Plasma concentration gradient influences the protein corona decoration on nanoparticles

(2012) Mahdi Ghavami et al.   RSC Advances

Toxicity Evaluations of Superparamagnetic Iron Oxide Nanoparticles: Cell “Vision” versus Physicochemical Properties of Nanoparticles

(2011) Morteza Mahmoudi et al.   ACS Nano

Magnetic fluid hyperthermia: Focus on superparamagnetic iron oxide nanoparticles

(2011) Sophie Laurent et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

A simplified method for synthesis of Fe3O4@PAA nanoparticles and its application for the removal of basic dyes

(2011) Yin-Yin Xu et al.   APPLIED SURFACE SCIENCE

Theranostics: Combining Imaging and Therapy

(2011) Sneha S. Kelkar et al.   BIOCONJUGATE CHEMISTRY

Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy

(2011) Mu-Yi Hua et al.   BIOMATERIALS

Dendronized iron oxide nanoparticles for multimodal imaging

(2011) Giuseppe Lamanna et al.   BIOMATERIALS

cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

(2011) Xiaoqiang Yang et al.   BIOMATERIALS

Silica Nanocapsules of Fluorescent Conjugated Polymers and Superparamagnetic Nanocrystals for Dual-Mode Cellular Imaging

(2011) Happy Tan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: Synthesis, stability, cytotoxicity and MR imaging

(2011) Christoph Schweiger et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Targeted drug delivery to tumors: Myths, reality and possibility

(2011) You Han Bae et al.   JOURNAL OF CONTROLLED RELEASE

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Magnetic Nanocarriers of Doxorubicin Coated with Poly(ethylene glycol) and Folic Acid: Relation between Coating Structure, Surface Properties, Colloidal Stability, and Cancer Cell Targeting

(2011) Karine Kaaki et al.   LANGMUIR

HSA Coated Iron Oxide Nanoparticles as Drug Delivery Vehicles for Cancer Therapy

(2011) Qimeng Quan et al.   MOLECULAR PHARMACEUTICS

Iron oxide nanoparticles for targeted cancer imaging and diagnostics

(2011) Joshua E. Rosen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Folate receptor targeted, carboxymethyl chitosan functionalized iron oxide nanoparticles: a novel ultradispersed nanoconjugates for bimodal imaging

(2011) Dipsikha Bhattacharya et al.   Nanoscale

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging

(2011) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Image-Guided Prostate Cancer Therapy Using Aptamer-Functionalized Thermally Cross-Linked Superparamagnetic Iron Oxide Nanoparticles

(2011) Mi Kyung Yu et al.   Small

Fluorescent, Superparamagnetic Nanospheres for Drug Storage, Targeting, and Imaging: A Multifunctional Nanocarrier System for Cancer Diagnosis and Treatment

(2010) Hoon-Sung Cho et al.   ACS Nano

Multifunctional Stable and pH-Responsive Polymer Vesicles Formed by Heterofunctional Triblock Copolymer for Targeted Anticancer Drug Delivery and Ultrasensitive MR Imaging

(2010) Xiaoqiang Yang et al.   ACS Nano

Chlorotoxin Labeled Magnetic Nanovectors for Targeted Gene Delivery to Glioma

(2010) Forrest M. Kievit et al.   ACS Nano

Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy

(2010) Morteza Mahmoudi et al.   ADVANCED DRUG DELIVERY REVIEWS

Cytotoxicity and Cell Cycle Effects of Bare and Poly(vinyl alcohol)-Coated Iron Oxide Nanoparticles in Mouse Fibroblasts

(2010) Morteza Mahmoudi et al.   ADVANCED ENGINEERING MATERIALS

Superparamagnetic iron oxide – Loaded poly (lactic acid)-d-α-tocopherol polyethylene glycol 1000 succinate copolymer nanoparticles as MRI contrast agent

(2010) Chandrasekharan Prashant et al.   BIOMATERIALS

Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging

(2010) Xiaoqiang Yang et al.   BIOMATERIALS

Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery

(2010) Omid Veiseh et al.   BIOMATERIALS

Multifunctional doxorubicin loaded superparamagnetic iron oxide nanoparticles for chemotherapy and magnetic resonance imaging in liver cancer

(2010) Jin Hee Maeng et al.   BIOMATERIALS

Multifunctional superparamagnetic nanocarriers with folate-mediated and pH-responsive targeting properties for anticancer drug delivery

(2010) Miao Guo et al.   BIOMATERIALS

Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (−) prostate cancers

(2010) Kyoungin Min et al.   BIOMATERIALS

Multi-functional magnetic nanoparticles for magnetic resonance imaging and cancer therapy

(2010) Murali M. Yallapu et al.   BIOMATERIALS

Image-Guided Breast Tumor Therapy Using a Small Interfering RNA Nanodrug

(2010) M. Kumar et al.   CANCER RESEARCH

EGFRvIII Antibody-Conjugated Iron Oxide Nanoparticles for Magnetic Resonance Imaging-Guided Convection-Enhanced Delivery and Targeted Therapy of Glioblastoma

(2010) C. G. Hadjipanayis et al.   CANCER RESEARCH

Magnetic Resonance Imaging Tracking of Stem Cells in Vivo Using Iron Oxide Nanoparticles as a Tool for the Advancement of Clinical Regenerative Medicine

(2010) Morteza Mahmoudi et al.   CHEMICAL REVIEWS

What the Cell “Sees” in Bionanoscience

(2010) Dorota Walczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Superparamagnetic Iron Oxide Nanotheranostics for Targeted Cancer Cell Imaging and pH-Dependent Intracellular Drug Release

(2010) Peng Zou et al.   MOLECULAR PHARMACEUTICS

Magnetically Vectored Nanocapsules for Tumor Penetration and Remotely Switchable On-Demand Drug Release

(2010) Seong Deok Kong et al.   NANO LETTERS

Integrin-targeting thermally cross-linked superparamagnetic iron oxide nanoparticles for combined cancer imaging and drug delivery

(2010) Mi Kyung Yu et al.   NANOTECHNOLOGY

Biocompatibility of Fe3O4nanoparticles evaluated byin vitrocytotoxicity assays using normal, glia and breast cancer cells

(2010) B Ankamwar et al.   NANOTECHNOLOGY

Multifunctional Nanomedicine Platform for Cancer Specific Delivery of siRNA by Superparamagnetic Iron Oxide Nanoparticles-Dendrimer Complexes

(2010) Oleh Taratula et al.   Current Drug Delivery

Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors

(2009) Esben K. U. Larsen et al.   ACS Nano

MRI-visible polymeric vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression

(2009) Guihua Chen et al.   BIOMATERIALS

Folic acid–Pluronic F127 magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications

(2009) Jia-Jyun Lin et al.   BIOMATERIALS

Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells

(2009) Tetsuya Osaka et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles

(2009) Morteza Mahmoudi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Positive hyaluronan/PEI/DNA complexes as a target-specific intracellular delivery to malignant breast cancer

(2009) Xiyang Sun et al.   DRUG DELIVERY

Combined Ultrasmall Superparamagnetic Particles of Iron Oxide–Enhanced and Diffusion-Weighted Magnetic Resonance Imaging Reliably Detect Pelvic Lymph Node Metastases in Normal-Sized Nodes of Bladder and Prostate Cancer Patients

(2009) Harriet C. Thoeny et al.   EUROPEAN UROLOGY

Superparamagnetic Iron Oxide Nanoparticles with Rigid Cross-linked Polyethylene Glycol Fumarate Coating for Application in Imaging and Drug Delivery

(2009) Morteza Mahmoudi et al.   Journal of Physical Chemistry C

Cytotoxicity of Uncoated and Polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles

(2009) Morteza Mahmoudi et al.   Journal of Physical Chemistry C

Progress in the preparation of magnetic nanoparticles for applications in biomedicine

(2009) A G Roca et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Gold Nanoparticles Can Induce the Formation of Protein-based Aggregates at Physiological pH

(2009) Dongmao Zhang et al.   NANO LETTERS

Multifunctional magnetic nanoparticles for targeted delivery

(2009) Arun Kumar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Thermoresponsive core–shell magnetic nanoparticles for combined modalities of cancer therapy

(2009) S Purushotham et al.   NANOTECHNOLOGY

The influence of protein adsorption on nanoparticle association with cultured endothelial cells

(2008) Morton S. Ehrenberg et al.   BIOMATERIALS

Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

(2008) Hanna L. Karlsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications

(2008) Sophie Laurent et al.   CHEMICAL REVIEWS

Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy

(2008) Andrew Z. Wang et al.   ChemMedChem

Validation of High Gradient Magnetic Field Based Drug Delivery to Magnetizable Implants Under Flow

(2008) Z.G. Forbes et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Preparation of Water-Dispersible and Biocompatible Iron Oxide Nanoparticles for MRI Agent

(2008) Yun Tack Lee et al.   IEEE TRANSACTIONS ON NANOTECHNOLOGY

Pluronic/chitosan shell cross-linked nanocapsules encapsulating magnetic nanoparticles

(2008) Ki Hyun Bae et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Optimal Design and Characterization of Superparamagnetic Iron Oxide Nanoparticles Coated with Polyvinyl Alcohol for Targeted Delivery and Imaging†

(2008) Morteza Mahmoudi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Biodistribution, Clearance, and Biocompatibility of Iron Oxide Magnetic Nanoparticles in Rats

(2008) Tapan K. Jain et al.   MOLECULAR PHARMACEUTICS

Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparticles

(2008) Conroy Sun et al.   Nanomedicine

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine

Nanoimmunoliposome delivery of superparamagnetic iron oxide markedly enhances targeting and uptake in human cancer cells in vitro and in vivo

(2008) Chengli Yang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies

(2008) Wei Wu et al.   Nanoscale Research Letters

Bio-functionalization of magnetite nanoparticles using an aminophosphonic acid coupling agent: new, ultradispersed, iron-oxide folate nanoconjugates for cancer-specific targeting

(2008) Manasmita Das et al.   NANOTECHNOLOGY

Inhibition of Tumor-Cell Invasion with Chlorotoxin-Bound Superparamagnetic Nanoparticles

(2008) Omid Veiseh et al.   Small

Magnetic and MR relaxation properties of avidin–biotin conjugated superparamagnetic nanoparticles

(2007) Ji-Ae Park et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Magnetic Colloids As Drug Vehicles

(2007) J.D.G. Durán et al.   JOURNAL OF PHARMACEUTICAL SCIENCES