Nanoparticles as delivery carriers for anticancer prodrugs

Lyotropic Liquid Crystalline Self-Assembly Material Behavior and Nanoparticulate Dispersions of a Phytanyl Pro-Drug Analogue of Capecitabine−A Chemotherapy Agent

(2011) Xiaojuan Gong et al.   ACS Applied Materials & Interfaces

Squalene Based Nanocomposites: A New Platform for the Design of Multifunctional Pharmaceutical Theragnostics

(2011) José L. Arias et al.   ACS Nano

Paclitaxel efficacy and toxicity in older women with metastatic breast cancer: combined analysis of CALGB 9342 and 9840

(2011) S. M. Lichtman et al.   ANNALS OF ONCOLOGY

Polymeric Micelles with Water-Insoluble Drug as Hydrophobic Moiety for Drug Delivery

(2011) Guolin Li et al.   BIOMACROMOLECULES

A paclitaxel-conjugated adenovirus vector for targeted drug delivery for tumor therapy

(2011) Lingling Shan et al.   BIOMATERIALS

Lamellar crystalline self-assembly behaviour and solid lipid nanoparticles of a palmityl prodrug analogue of Capecitabine—A chemotherapy agent

(2011) Xiaojuan Gong et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Interaction of an amphiphilic squalenoyl prodrug of gemcitabine with cellular membranes

(2011) L. Bildstein et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Preparation and characterization of polymeric pH-sensitive STEALTH® nanoparticles for tumor delivery of a lipophilic prodrug of paclitaxel

(2011) B.B. Lundberg   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Quantitative nanoparticle tracking: applications to nanomedicine

(2011) Feiran Huang et al.   Nanomedicine

In vivoreal-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios

(2011) Chih-Jen Wen et al.   Nanomedicine

Prodrugs--from Serendipity to Rational Design

(2011) K. M. Huttunen et al.   PHARMACOLOGICAL REVIEWS

Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

(2011) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective targeting of 2′-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro

(2010) Kara L. Vine et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Squalenoyl nucleoside monophosphate nanoassemblies: New prodrug strategy for the delivery of nucleotide analogues

(2010) Joachim Caron et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Development of a novel prodrug of paclitaxel that is cleaved by prostate-specific antigen: An in vitro and in vivo evaluation study

(2010) Bakheet Elsadek et al.   EUROPEAN JOURNAL OF CANCER

Is there a role for mitomycin C in metastatic colorectal cancer?

(2010) Anastasios Dimou et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: An original drug delivery pathway

(2010) L. Bildstein et al.   JOURNAL OF CONTROLLED RELEASE

Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles

(2010) Igor V. Zhigaltsev et al.   JOURNAL OF CONTROLLED RELEASE

Pharmacokinetics and Physiologically-Based Pharmacokinetic Modeling of Nanoparticles

(2010) Raymond S. H. Yang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Prodrugs: Some Thoughts and Current Issues

(2010) Valentino J. Stella   JOURNAL OF PHARMACEUTICAL SCIENCES

Amphiphilic curcumin conjugate-forming nanoparticles as anticancer prodrug and drug carriers:in vitroandin vivoeffects

(2010) Huadong Tang et al.   Nanomedicine

Nanomicellar formulations for sustained drug delivery: strategies and underlying principles

(2010) Ruchit Trivedi et al.   Nanomedicine

Nanostructured nanoparticles of self-assembled lipid pro-drugs as a route to improved chemotherapeutic agents

(2010) Sharon M. Sagnella et al.   Nanoscale

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

(2010) N. Kolishetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular-protein-enhanced cellular uptake of squalenoyl gemcitabine from nanoassemblies

(2010) Lucien Bildstein et al.   Soft Matter

Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis

(2010) Neeraj Vij et al.   JOURNAL OF NANOBIOTECHNOLOGY

Magnetic nanoparticles for theragnostics

(2009) Veronica I. Shubayev et al.   ADVANCED DRUG DELIVERY REVIEWS

Heparin−Paclitaxel Conjugates as Drug Delivery System: Synthesis, Self-Assembly Property, Drug Release, and Antitumor Activity

(2009) Ying Wang et al.   BIOCONJUGATE CHEMISTRY

Current Prodrug Design for Drug Discovery

(2009) Pei-Wen Hsieh et al.   CURRENT PHARMACEUTICAL DESIGN

Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells

(2009) Yuta Ishii et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Freeze-drying of squalenoylated nucleoside analogue nanoparticles

(2009) L. Bildstein et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a positively charged prednicarbate nanoemulsion

(2009) Yücel Baspinar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra(R), TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome

(2009) Azra Raza et al.   Journal of Hematology & Oncology

Polyvalent Oligonucleotide Gold Nanoparticle Conjugates as Delivery Vehicles for Platinum(IV) Warheads

(2009) Shanta Dhar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stabilization of the Nitric Oxide (NO) Prodrugs and Anticancer Leads, PABA/NO and Double JS-K, through Incorporation into PEG-Protected Nanoparticles

(2009) Varun Kumar et al.   MOLECULAR PHARMACEUTICS

The Use of Amino Acid Linkers in the Conjugation of Paclitaxel with Hyaluronic Acid as Drug Delivery System: Synthesis, Self-Assembled Property, Drug Release, and In Vitro Efficiency

(2009) Dingcheng Xin et al.   PHARMACEUTICAL RESEARCH

Tissue Specific Cytotoxicity of Colon Cancer Cells Mediated by Nanoparticle-delivered Suicide Gene In vitro and In vivo

(2008) G. Zhang et al.   CLINICAL CANCER RESEARCH

Polymeric Tubulysin-Peptide Nanoparticles with Potent Antitumor Activity

(2008) T. Schluep et al.   CLINICAL CANCER RESEARCH

Potential of solid lipid nanoparticles in brain targeting

(2008) Indu Pal Kaur et al.   JOURNAL OF CONTROLLED RELEASE

Modulating the Therapeutic Activity of Nanoparticle Delivered Paclitaxel by Manipulating the Hydrophobicity of Prodrug Conjugates

(2008) Steven M. Ansell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Magnetoresponsive Squalenoyl Gemcitabine Composite Nanoparticles for Cancer Active Targeting

(2008) José L. Arias et al.   LANGMUIR

Microtubule Acetylation Through HDAC6 Inhibition Results in Increased Transfection Efficiency

(2008) Erin E Vaughan et al.   MOLECULAR THERAPY

In Vitro and In Vivo Evaluation of Microparticulate Drug Delivery Systems Composed of Macromolecular Prodrugs

(2008) Hiraku Onishi et al.   MOLECULES

Polyvalent DNA Nanoparticle Conjugates Stabilize Nucleic Acids

(2008) Dwight S. Seferos et al.   NANO LETTERS

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY

Concept and Clinical Evaluation of Carrier-Mediated Anticancer Agents

(2008) W. C. Zamboni   ONCOLOGIST

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incorporation of novel 1-alkylcarbonyloxymethyl prodrugs of 5-fluorouracil into poly(lactide-co-glycolide) nanoparticles

(2007) P MCCARRON et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Self-assembled drug delivery systems

(2007) Yiguang Jin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Brain targeting using novel lipid nanovectors

(2007) Arnaud Béduneau et al.   JOURNAL OF CONTROLLED RELEASE