Targeted nanotheranostics for personalized cancer therapy

Long-circulating perfluorooctyl bromide nanocapsules for tumor imaging by 19FMRI

(2012) Odile Diou et al.   BIOMATERIALS

Conformation of surface-decorating dextran chains affects the pharmacokinetics and biodistribution of doxorubicin-loaded nanoparticles

(2012) Khairallah Alhareth et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound

(2012) Holger Grüll et al.   JOURNAL OF CONTROLLED RELEASE

Molecular Imaging with Theranostic Nanoparticles

(2011) Jesse V. Jokerst et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cancer Nanotheranostics: Improving Imaging and Therapy by Targeted Delivery Across Biological Barriers

(2011) Forrest M. Kievit et al.   ADVANCED MATERIALS

Nanomaterials: Applications in Cancer Imaging and Therapy

(2011) José A. Barreto et al.   ADVANCED MATERIALS

Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound

(2011) Ayele H. Negussie et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Efficient nano iron particle-labeling and noninvasive MR imaging of mouse bone marrow-derived endothelial progenitor cells

(2011) Chen et al.   International Journal of Nanomedicine

A pharmaceutical study of doxorubicin-loaded PEGylated nanoparticles for magnetic drug targeting

(2011) J. Gautier et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Ultrasound Molecular Imaging of Tumor Angiogenesis With an Integrin Targeted Microbubble Contrast Agent

(2011) Christopher R. Anderson et al.   INVESTIGATIVE RADIOLOGY

High intensity focused ultrasound ablation: A new therapeutic option for solid tumors

(2011) Lian Zhang et al.   Journal of Cancer Research and Therapeutics

Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions

(2011) Natalya Rapoport et al.   JOURNAL OF CONTROLLED RELEASE

A generalized strategy for designing 19F/1H dual-frequency MRI coil for small animal imaging at 4.7 Tesla

(2011) Lingzhi Hu et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Water-Dispersible Sugar-Coated Iron Oxide Nanoparticles. An Evaluation of their Relaxometric and Magnetic Hyperthermia Properties

(2011) Lenaic Lartigue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systematic Study of Protein Detection Mechanism of Self-Assembling19F NMR/MRI Nanoprobes toward Rational Design and Improved Sensitivity

(2011) Yousuke Takaoka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

19F MRI detection of acute allograft rejection with in vivo perfluorocarbon labeling of immune cells

(2011) T. Kevin Hitchens et al.   MAGNETIC RESONANCE IN MEDICINE

Simultaneous dual-nuclei imaging for motion corrected detection and quantification of19F imaging agents

(2011) Jochen Keupp et al.   MAGNETIC RESONANCE IN MEDICINE

Quantitative tissue oxygen measurement in multiple organs using 19F MRI in a rat model

(2011) Siyuan Liu et al.   MAGNETIC RESONANCE IN MEDICINE

Molecular-targeted nanotherapies in cancer: Enabling treatment specificity

(2011) Elvin Blanco et al.   Molecular Oncology

Nanomaterials for cancer therapy and imaging

(2011) Ki Hyun Bae et al.   MOLECULES AND CELLS

Nanoparticle PEGylation for imaging and therapy

(2011) Jesse V Jokerst et al.   Nanomedicine

High sensitivity 19F MRI of a perfluorooctyl bromide emulsion: application to a dynamic biodistribution study and oxygen tension mapping in the mouse liver and spleen

(2011) Céline Giraudeau et al.   NMR IN BIOMEDICINE

Image-Guided Prostate Cancer Therapy Using Aptamer-Functionalized Thermally Cross-Linked Superparamagnetic Iron Oxide Nanoparticles

(2011) Mi Kyung Yu et al.   Small

Ultrasound-Triggered Drug Release and Enhanced Anticancer Effect of Doxorubicin-Loaded Poly(D,L-Lactide-Co-Glycolide)-Methoxy-Poly(Ethylene Glycol) Nanodroplets

(2011) Lina Du et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Attenuation of Mouse Melanoma by A/C Magnetic Field after Delivery of Bi-Magnetic Nanoparticles by Neural Progenitor Cells

(2010) Raja Shekar Rachakatla et al.   ACS Nano

Single-Step Assembly of Homogenous Lipid−Polymeric and Lipid−Quantum Dot Nanoparticles Enabled by Microfluidic Rapid Mixing

(2010) Pedro M. Valencia et al.   ACS Nano

Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging

(2010) Xiaoqiang Yang et al.   BIOMATERIALS

Noninvasive visualization of in vivo release and intratumoral distribution of surrogate MR contrast agent using the dual MR contrast technique

(2010) Yoshinori Onuki et al.   BIOMATERIALS

Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery

(2010) Omid Veiseh et al.   BIOMATERIALS

Image-Guided Breast Tumor Therapy Using a Small Interfering RNA Nanodrug

(2010) M. Kumar et al.   CANCER RESEARCH

Quantitative 1H MRI, 19F MRI, and 19F MRS of cell-internalized perfluorocarbon paramagnetic nanoparticles

(2010) Maarten B. Kok et al.   Contrast Media & Molecular Imaging

A novel 19F agent for detection and quantification of human dendritic cells using magnetic resonance imaging

(2010) Fernando Bonetto et al.   INTERNATIONAL JOURNAL OF CANCER

Ultrasound-triggered release of materials entrapped in microbubble–liposome constructs: A tool for targeted drug delivery

(2010) Alexander L. Klibanov et al.   JOURNAL OF CONTROLLED RELEASE

Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo

(2010) Gavin D. Kenny et al.   JOURNAL OF CONTROLLED RELEASE

Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: An in vivo proof-of-concept study

(2010) Mariska de Smet et al.   JOURNAL OF CONTROLLED RELEASE

Mesenchymal Stem Cells in the Pathogenesis and Therapy of Breast Cancer

(2010) Christelle P. El-Haibi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

PEGylated Amyloid Peptide Nanocontainer Delivery and Release System

(2010) V. Castelletto et al.   LANGMUIR

Superparamagnetic Iron Oxide Nanotheranostics for Targeted Cancer Cell Imaging and pH-Dependent Intracellular Drug Release

(2010) Peng Zou et al.   MOLECULAR PHARMACEUTICS

Functional nanoparticles for molecular imaging guided gene delivery

(2010) Gang Liu et al.   Nano Today

Monitoring of magnetic targeting to tumor vasculature through MRI and biodistribution

(2010) Evin Gultepe et al.   Nanomedicine

Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: What should be the policy?

(2010) Babak Kateb et al.   NEUROIMAGE

In vivo mapping of tumor oxygen consumption using 19F MRI relaxometry

(2010) Caroline Diepart et al.   NMR IN BIOMEDICINE

Delivery of Water-Soluble Drugs Using Acoustically Triggered Perfluorocarbon Double Emulsions

(2010) Mario L. Fabiilli et al.   PHARMACEUTICAL RESEARCH

All-in-One Target-Cell-Specific Magnetic Nanoparticles for Simultaneous Molecular Imaging and siRNA Delivery

(2009) Jae-Hyun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of 19F magnetic resonance to study the efficacy of fluorine labeled drugs in the three-dimensional cultured breast cancer cells

(2009) Dorota Bartusik et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Self-assembly of pH-responsive fluorinated dendrimer-based particulates for drug delivery and noninvasive imaging

(2009) Jason M. Criscione et al.   BIOMATERIALS

Heat-sensitive microbubbles for intraoperative assessment of cancer ablation margins

(2009) Jiwei Huang et al.   BIOMATERIALS

Multiparametric Monitoring of Tumor Response to Chemotherapy by Noninvasive Imaging

(2009) Z. Medarova et al.   CANCER RESEARCH

Ultrasound, liposomes, and drug delivery: principles for using ultrasound to control the release of drugs from liposomes

(2009) Avi Schroeder et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Progress towards personalized medicine

(2009) Stewart Bates   DRUG DISCOVERY TODAY

Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides

(2009) Todd A. Aguilera et al.   Integrative Biology

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

(2009) Neelesh R. Soman et al.   JOURNAL OF CLINICAL INVESTIGATION

Detection of fluorine labeled Herceptin using cellular 19F MRI ex vivo

(2009) Dorota Bartusik et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Perfluorocarbon-loaded shell crosslinked knedel-like nanoparticles: Lessons regarding polymer mobility and self-assembly

(2009) Andreas M. Nyström et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

A Temperature-Sensitive Liposomal1H CEST and19F Contrast Agent for MR Image-Guided Drug Delivery

(2009) Sander Langereis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalized Nanoparticles with Long-Term Stability in Biological Media

(2009) Chen Fang et al.   Small

Ultrasound triggered cell death in vitro with doxorubicin loaded poly lactic-acid contrast agents

(2009) J.R. Eisenbrey et al.   ULTRASONICS

19F- and Fluorescently Labeled Micelles as Nanoscopic Assemblies for Chemotherapeutic Delivery

(2008) Wenjun Du et al.   BIOCONJUGATE CHEMISTRY

Amphiphilic Hyperbranched Fluoropolymers as Nanoscopic19F Magnetic Resonance Imaging Agent Assemblies

(2008) Wenjun Du et al.   BIOMACROMOLECULES

Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy

(2008) Andrew Z. Wang et al.   ChemMedChem

Detection of targeted perfluorocarbon nanoparticle binding using19F diffusion weighted MR spectroscopy

(2008) Emily A. Waters et al.   MAGNETIC RESONANCE IN MEDICINE

Gadolinium-modulated19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging

(2008) Anne M. Neubauer et al.   MAGNETIC RESONANCE IN MEDICINE

In vivo “hot spot” MR imaging of neural stem cells using fluorinated nanoparticles

(2008) Jesús Ruiz-Cabello et al.   MAGNETIC RESONANCE IN MEDICINE

Perfluorohexane-loaded Macrophages as a Novel Ultrasound Contrast Agent: A Feasibility Study

(2008) Liselotte M. Kornmann et al.   MOLECULAR IMAGING AND BIOLOGY

Synthesis and Characterization of Stable Fluorocarbon Nanostructures as Drug Delivery Vehicles for Cytolytic Peptides

(2008) Neelesh R. Soman et al.   NANO LETTERS

Targeted Delivery of Nanoparticles Bearing Fibroblast Growth Factor-2 by Ultrasonic Microbubble Destruction for Therapeutic Arteriogenesis

(2008) John C. Chappell et al.   Small

Acoustically active perfluorocarbon nanoemulsions as drug delivery carriers for camptothecin: Drug release and cytotoxicity against cancer cells

(2008) Jia-You Fang et al.   ULTRASONICS

Paramagnetic Relaxation-Based19F MRI Probe To Detect Protease Activity

(2007) Shin Mizukami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY