Telomeres and disease

Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA)

(2009) M. Hills et al.   BLOOD

Dyskeratosis Congenita

(2009) Sharon A. Savage et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

(2009) Peter J. Cook et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia

(2009) R. T. Calado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

(2008) Sharon A. Savage et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Telomeres, stem cells, and hematology

(2008) P. M. Lansdorp   BLOOD

Telomere maintenance and human bone marrow failure

(2008) R. T. Calado et al.   BLOOD

Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers

(2008) Nada Farhat et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer

(2008) Ji Un Kang et al.   CANCER GENETICS AND CYTOGENETICS

Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

(2008) Ying Cao et al.   CANCER SCIENCE

Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing

(2008) L. S.M. Wong et al.   CARDIOVASCULAR RESEARCH

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks

(2008) C.A. Bañuelos et al.   DNA REPAIR

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

(2008) Yufei Wang et al.   NATURE GENETICS

Lung cancer susceptibility locus at 5p15.33

(2008) James D McKay et al.   NATURE GENETICS

Telomeres and Aging

(2008) Geraldine Aubert et al.   PHYSIOLOGICAL REVIEWS

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age to survive: DNA damage and aging

(2008) Björn Schumacher et al.   TRENDS IN GENETICS

Systemic adaptation to oxidative challenge induced by regular exercise

(2007) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dyskeratosis Congenita: A historical perspective

(2007) Amanda J. Walne et al.   MECHANISMS OF AGEING AND DEVELOPMENT