Mechanical Stimulation of Growth Plate Chondrocytes: Previous Approaches and Future Directions

In situ deformation of growth plate chondrocytes in stress-controlled static vs dynamic compression

(2017) Elizabeth A. Zimmermann et al.   JOURNAL OF BIOMECHANICS

Mechanical loading regulates organization of the actin cytoskeleton and column formation in postnatal growth plate

(2017) Christy H. Killion et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of mechanical stress on chondrocyte phenotype and chondrocyte extracellular matrix expression

(2016) Qiang Liu et al.   Scientific Reports

A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

(2015) E. Kozhemyakina et al.   DEVELOPMENT

Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up

(2015) Alberto Roselló-Díez et al.   ENDOCRINE REVIEWS

Placenta-on-a-chip: a novel platform to study the biology of the human placenta

(2015) Ji Soo Lee et al.   Journal of Maternal-Fetal & Neonatal Medicine

Compressive mechanical modulation alters the viability of growth plate chondrocytes in vitro

(2015) Rosa Kaviani et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

A dynamic cell adhesion surface regulates tissue architecture in growth plate cartilage

(2014) S. M. Romereim et al.   DEVELOPMENT

In vivo dynamic loading reduces bone growth without histomorphometric changes of the growth plate

(2014) Anne-Laure Ménard et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Microfabrication of human organs-on-chips

(2013) Dongeun Huh et al.   Nature Protocols

Organs-on-a-Chip: A Focus on Compartmentalized Microdevices

(2011) Christopher Moraes et al.   ANNALS OF BIOMEDICAL ENGINEERING

In vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation

(2011) Barthélémy Valteau et al.   BONE

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

Semi-confined compression of microfabricated polymerized biomaterial constructs

(2011) Christopher Moraes et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Valve-based microfluidic compression platform: single axon injury and regrowth

(2011) Suneil Hosmane et al.   LAB ON A CHIP

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Cell polarity

(2011) Sarah M. Romereim et al.   Organogenesis

Tissue and cellular morphological changes in growth plate explants under compression

(2010) Samira Amini et al.   JOURNAL OF BIOMECHANICS

Growth plate explants respond differently to in vitro static and dynamic loadings

(2010) Kim Sergerie et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

A microfabricated platform for high-throughput unconfined compression of micropatterned biomaterial arrays

(2009) Christopher Moraes et al.   BIOMATERIALS

Absence of Filamin A Prevents Cells from Responding to Stiffness Gradients on Gels Coated with Collagen but not Fibronectin

(2009) Fitzroy J. Byfield et al.   BIOPHYSICAL JOURNAL

Growth plate mechanics and mechanobiology. A survey of present understanding

(2009) Isabelle Villemure et al.   JOURNAL OF BIOMECHANICS

Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation

(2009) Christopher Moraes et al.   LAB ON A CHIP

The Effect of Mechanical Loading on the Metabolism of Growth Plate Chondrocytes

(2008) Masashi Ueki et al.   ANNALS OF BIOMEDICAL ENGINEERING

Molecular analysis of chondrocytes cultured in agarose in response to dynamic compression

(2008) Carole Bougault et al.   BMC BIOTECHNOLOGY

Effects of in vivo static compressive loading on aggrecan and type II and X collagens in the rat growth plate extracellular matrix

(2008) Mathilde Cancel et al.   BONE

Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

(2008) K. K. Mak et al.   DEVELOPMENT