Article
Engineering, Aerospace
Zhe Dong, Yongzeng Li, Lingrui Jiao, Weiguo Zhang, Yingzheng Liu, Di Peng
Summary: A novel speckle pattern pressure-sensitive paint (PSP) system integrating the single-shot lifetime method and stereo digital image correlation (DIC) technique was proposed in this work. This system was successfully applied to measure the instantaneous pressure and deformation field of a high-speed rotating blade, showing highly consistent results with the regular PSP.
AEROSPACE SCIENCE AND TECHNOLOGY
(2022)
Article
Optics
Chuanguo Xiong, Yuhan Gao, Yuhua Huang, Fulong Zhu
Summary: In this study, a projected-speckle deflectometry based on the digital image correlation technique is proposed to solve the issues of out-of-focus image acquisition and ambient light interference in traditional deflectometry techniques. The measurement accuracy of the system is validated through quantitative deformation experiments and comparison with other measurement methods. The effects of projector vibration, electronic noise, and out-of-plane movements on measurement results are also analyzed.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Y. Wang, Y. Gao, Y. Liu, Z. Gao, Y. Su, Q. Zhang
Summary: The study captured speckle images with different apertures and speckle generation parameters, and evaluated the corresponding measurement errors. The optimal speckle generation parameters were experimentally determined to be consistent with existing theoretical models. The optimal aperture was found to be 5.6, as excessively large or small F-numbers would reduce measurement accuracy.
EXPERIMENTAL MECHANICS
(2021)
Article
Engineering, Multidisciplinary
Bing Pan, Xiaoying Zhang, Yang Lv, Liping Yu
Summary: This study presents a method for automatically determining the optimal camera exposure time for high-quality deformation measurement. The method can adaptively output high-quality deformed images, resulting in better speckle pattern quality and DIC measurement accuracy.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2022)
Article
Optics
Yuan Yuan, Zhirui Wu, Feng Zheng, Kehan He, Chen Ding
Summary: In this paper, a pointwise shape functions-assisted subset selection (SFSS) strategy for digital image correlation (DIC) was proposed. The subset size could be continuously adjusted in subpixel level through introducing the Butterworth window function. The feasibility and effectiveness of the SFSS strategy were verified by a series of synthetic speckle images, showing enhanced measurement accuracy and precision in DIC algorithm.
OPTICS AND LASER TECHNOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Shengjia Wang, Yingjie Feng, Shuai Gao, Pengyuan Shi, Jianxuan Xiong, Pengfei Huang, Jiabin Wang, Zhan Gao, Sijin Wu, Weimin Sun
Summary: Proposal of a mechanical quantity sensing framework based on fiber-coupled common-path shearography for simultaneous measurement of deformation and slope. Optical fiber is used to generate holograms without breaking the common-path structure. Features include zero-approaching shear amount, separate control of spatial carriers, and scrambled reference wave. Single-shot phase measurement scheme is implemented by the spatial carrier method. Fiber scrambling is used to enhance the phase map quality. Physical principle demonstrated, and preliminary experiments verify the feasibility and functionality of the framework.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Multidisciplinary
Yifei Zhou, Qianjiang Zuo, Licheng Zhou, Bao Yang, Zejia Liu, Yiping Liu, Liqun Tang, Shoubin Dong, Zhenyu Jiang
Summary: A novel method is proposed to assess the quality of speckle patterns for deformation measurement. This method utilizes image features essential for image registration and provides sensitive detection of subtle differences between speckle patterns. It also offers reliable guidelines for designing high-quality transferable speckle patterns.
Article
Engineering, Multidisciplinary
Hongfu Xie, Jie Wang, Zhen Wang, Chong Zhao, Jiecun Liang, Xide Li
Summary: In this article, an in situ high-temperature testing system is reported, which allows for observation and measurement of deformations in advanced hot-section materials at high temperatures. The combination of SEM-DIC technique and Al2O3 nanoscale particles was used to investigate the high-temperature tensile and creep properties of NBSCS alloy at 750 degrees C. The scanning-DIC method was applied to calculate full-field dynamic displacement and strain, revealing that strain concentrations usually occur at crack initiation or propagation sites.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2021)
Review
Materials Science, Multidisciplinary
L. Yu, B. Pan
Summary: This overview comprehensively summarizes the challenges and recent advances in high-temperature DIC techniques, including the basic principles, challenges, and corresponding countermeasures of high-temperature DIC. Additionally, typical applications of high-temperature DIC at various spatial scales are briefly described.
EXPERIMENTAL MECHANICS
(2021)
Article
Engineering, Multidisciplinary
Ruiyang Wang, Xinwei Zhang, Dahai Li
Summary: Traditional phase measuring deflectometry and digital image correlation based deflectometry have limitations in dynamic measurement, while our proposed single-shot dynamic speckle deflectometry offers a solution with validated accuracy and robustness through numerical simulations and practical measurements.
Article
Engineering, Multidisciplinary
Zhenning Liang, Jinxiu Zhang, Longhui Qiu, Guangyi Lin, Fengfu Yin
Summary: The digital image correlation technique with non-fixed camera is developed for deformation measurement in the field, providing a more flexible and convenient method to measure deformation of high altitude facilities. Multiple images and feature templates are used for correction to ensure accuracy.
Article
Optics
Appurva Jain, Abhishek Mishra, Vikrant Tiwari, Gurminder Singh, Ravinder Pal Singh, Sunpreet Singh
Summary: This paper proposes a DIC deformation measurement method based on the integer-pixel matching approach, which provides full field measurements and has the advantages of non-contact and high precision. The proposed method not only enables displacement invariance measurement with robustness and high efficiency, but also achieves an average accuracy of 0.1% in stress-strain results.
Article
Optics
Yao Huang, Xianfu Huang, Menglin Zhonga, Zhanwei Liu
Summary: A bilayer color digital image correlation (BC-DIC) method is reported for measuring the topography of a liquid interface. The method uses the refraction of speckle patterns at the interface to perform 3D reconstruction through 2D measurement. It is shown to be feasible and accurate for measuring the topography of transparent objects, including liquid interfaces.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Optics
Zhisong Li, Ping Zhong, Yu Chen, Xin Tang, Yinrui Gao, Haowei Hu
Summary: In this study, a 3D deformation measurement method based on DSPI and DSSPI was proposed, which outperforms traditional methods in optical arrangement, cost, and detection efficiency. Phase maps obtained by space carrier method provide both in-plane and out-of-plane deformation information, enabling the calculation of 3D deformation distribution through integral operation. Experimental results confirm the validity of the proposed method.
OPTICS COMMUNICATIONS
(2021)
Article
Physics, Multidisciplinary
Yonghong Wang, Xiao Zhang, Qihan Zhao, Yanfeng Yao, Peizheng Yan, Biao Wang
Summary: We propose a novel system that uses a single camera to synchronously measure out-of-plane deformation and two orthogonal slopes. The linearly polarized reference beam interferes with the unpolarized object beam to measure the out-of-plane deformation, while a modified Mach-Zehnder interferometer is used to measure the two orthogonal slopes. This method has been proven effective through experiments on pressure-loaded circular plates.
Article
Engineering, Biomedical
Feng Lin, Yue Shao, Xufeng Xue, Yi Zheng, Zida Li, Chunyang Xiong, Jianping Fu
ACTA BIOMATERIALIA
(2019)
Article
Chemistry, Multidisciplinary
Pengfei Yang, Zhepeng Zhang, Mengxing Sun, Feng Lin, Ting Cheng, Jianping Shi, Chunyu Xie, Yuping Shi, Shaolong Jiang, Yahuan Huan, Porun Liu, Feng Ding, Chunyang Xiong, Dan Xie, Yanfeng Zhang
Article
Engineering, Biomedical
Haihui Zhang, Feng Lin, Jianyong Huang, Chunyang Xiong
ACTA BIOMATERIALIA
(2020)
Article
Nanoscience & Nanotechnology
Yu Hei, Binhong Teng, Ziqian Zeng, Siqi Zhang, Qian Li, Jijia Pan, Zuyuan Luo, Chunyang Xiong, Shicheng Wei
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2020)
Article
Chemistry, Multidisciplinary
Zuoying Yuan, Xiaojing Yuan, Yuming Zhao, Qing Cai, Yue Wang, Ruochen Luo, Shi Yu, Yuanyuan Wang, Jianmin Han, Lihong Ge, Jianyong Huang, Chunyang Xiong
Summary: The study focuses on preparing porous shape-memory cryogel microspheres (CMS) with a certain pore size from methacrylated gelatin (GelMA), which effectively delivers multiple cells and enhances cell viability. Results indicate the potential of this technique in promoting tissue regeneration, especially in bone tissue engineering.
Article
Engineering, Mechanical
Yajun Zhang, Xiaoning Yang, Chunyang Xiong
Summary: Quantifying the mechanical properties of silicone gels is essential for studying cell responses in microenvironments. A new nanoindentation technique was designed to address high surface energy materials and understand the material's dependence on composition ratios. This research paves the way for more precise exploration of the interaction between cells and extracellular matrix in mechanobiology.
ACTA MECHANICA SINICA
(2021)
Article
Biophysics
Qunfeng Yang, Nan Jiang, Hongwei Xu, Yajun Zhang, Chunyang Xiong, Jianyong Huang
Summary: Cells in living organisms exist in multiphysics-coupled environments, where exogenous electric fields and extracellular stiffness gradients can regulate cell movement and polarization. Research shows that cell responses to these electromechanical cues are nonlinear and can be integrated through cooperation and competition mechanisms. This work provides insights into how cells sense and respond to multiple cues for migration and polarization, with implications for physiological and pathological processes.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Multidisciplinary
Yu Hei, Yang Chen, Qian Li, Zi Mei, Jijia Pan, Siqi Zhang, Chunyang Xiong, Xiaodong Su, Shicheng Wei
Summary: The authors have developed a multifunctional immunoliposome containing CAR, aCD47, and aPDL1, which can effectively reprogram the immunosuppressive TME by releasing aCD47 to promote phagocytosis of tumor cells and activating CTLs, and exposing aPDL1 to block the PD-1/PD-L1 signaling pathway for inducing CTLs to kill tumor cells. This approach holds great potential in enhancing the immunotherapeutic efficiency of aPDL1 against primary cancer and metastasis by inhibiting angiogenesis and reducing adrenergic nerves in tumor tissues.
Article
Engineering, Biomedical
Yike Gao, Zuoying Yuan, Xiaojing Yuan, Zhuo Wan, Yingjie Yu, Qi Zhan, Yuming Zhao, Jianmin Han, Jianyong Huang, Chunyang Xiong, Qing Cai
Summary: The study showed that hypoxic preconditioning can enhance exosome secretion from SHEDs stem cells, and these hypoxic exosomes exhibit superior potential in promoting cellular angiogenesis and osteogenesis. The development of PMS-PDA porous microsphere delivery technology effectively achieved the delivery and sustained release of hypoxic exosomes.
BIOACTIVE MATERIALS
(2022)
Article
Engineering, Biomedical
Xiaojing Yuan, Zuoying Yuan, Yuanyuan Wang, Zhuo Wan, Xiaotong Wang, Shi Yu, Jianmin Han, Jianyong Huang, Chunyang Xiong, Lihong Ge, Qing Cai, Yuming Zhao
Summary: This study presents a novel injectable system that incorporates stem cells from human exfoliated deciduous teeth (SHEDs) and simvastatin (SIM) into gelatin methacrylate (GelMA) cryogel microspheres (SMS). The system promotes SHEDs adhesion, proliferation, odontogenic differentiation, and angiogenic potential. Subcutaneous implantation of SHEDs/SMS induces vessel-rich pulp-like tissue regeneration, highlighting the potential for clinical application in endodontic regenerative dentistry.
MATERIALS TODAY BIO
(2022)
Article
Biology
Qing Zhang, Feng Lin, Jianyong Huang, Chunyang Xiong
Summary: Cell phenotype heterogeneity within tumor tissue, especially due to epithelial-mesenchymal transition (EMT), plays a role in cancer invasion and metastasis. In this study, heterotypic tumor spheroids containing both epithelial and EMT cancer cells were generated and it was found that EMT cells dominated the periphery of the spheroid. Furthermore, EMT cells acted as leader cells to enhance the migration efficiency of epithelial cancer cells and promote dispersion and invasion of the spheroids through force transition and heterophilic N-cadherin/E-cadherin adhesion complexes. Impairment of this adhesion complex formation prevented EMT cells from guiding epithelial cancer cell migration and blocked the dispersion of tumor spheroids.
SCIENCE CHINA-LIFE SCIENCES
(2022)
Article
Cell Biology
Qing Zhang, Pudi Wang, Xu Fang, Feng Lin, Jing Fang, Chunyang Xiong
Summary: Cell-ECM interactions play a crucial role in triggering signal pathways and regulating cellular functions. The collagen gel contraction assay provides a mechanically associated readout of 3D cellular contractility and is widely used in studying cell-ECM interactions.
EUROPEAN JOURNAL OF CELL BIOLOGY
(2022)
Article
Chemistry, Analytical
Xu Fang, Pudi Wang, Feng Lin, Jianyong Huang, Jing Fang, Chunyang Xiong
Summary: In this study, a ridge structure was incorporated into the membrane surface of a traditional pneumatic cavity stretching chip to regulate the strain mode. The results showed that the ridge structure could change the equiaxial stretching mode to the standard uniaxial strain, and it was independent of ridge width. The study also demonstrated the ability to realize multimodal strain fields and achieve high-throughput testing.
Article
Materials Science, Biomaterials
Yue Xu, Chuanwen Guo, Xueyi Yang, Weihong Yuan, Xu Zhang, Yujie Sun, Gang Wen, Linbo Wang, Hui Li, Chunyang Xiong, Chun Yang
Summary: Cell traction plays an important role in the biochemical and mechanical interactions between cell and extracellular matrix. Traction force microscopy (TFM) is a powerful technique for quantitative analysis at cellular scale. However, current TFM faces challenges in characterizing macromolecular scale traction events due to limited sampling density and algorithmic precision. This article introduces a super-resolution TFM using a novel substrate surface modification method, achieving spatial resolution comparable to fluorescence microscopy and precision comparable to the rupture force of an integrin-ligand bond. Correlated imaging with fluorescence microscopy reveals the high correlation between residing paxillin and traction, while alpha 5 integrin shows different localization. Time-lapse TFM imaging captures transient traction variation as the adhesion protein passes by. Therefore, the novel super-resolution TFM benefits the study of cellular biochemical and mechanical interactions.
BIOMATERIALS SCIENCE
(2023)
Article
Cell Biology
Xingchen Li, Yuan Cheng, Zhiqi Wang, Jingyi Zhou, Yuanyuan Jia, Xiangjun He, Lijun Zhao, Yangyang Dong, Yuan Fan, Xiao Yang, Boqiang Shen, Xiaotong Wu, Jiaqi Wang, Chunyang Xiong, Lihui Wei, Xiaoping Li, Jianliu Wang
CELL DEATH & DISEASE
(2020)
