Fetoplacental Vascular Endothelial Dysfunction as an Early Phenomenon in the Programming of Human Adult Diseases in Subjects Born from Gestational Diabetes Mellitus or Obesity in Pregnancy

Obesity, blood vessels and metabolic syndrome

(2011) M. Tesauro et al.   Acta Physiologica

Is it time to revisit the Pedersen hypothesis in the face of the obesity epidemic?

(2011) Patrick M. Catalano et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Alterações vasculares em ratos obesos por dieta rica em gordura: papel da Via L-arginina/NO Endotelial

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Diabetic embryopathy: A role for the epigenome?

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Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice

(2011) Satomi Kagota et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functional Link Between Adenosine and Insulin: A Hypothesis for Fetoplacental Vascular Endothelial Dysfunction in Gestational Diabetes

(2011) Enrique Guzman-Gutierrez et al.   Current Vascular Pharmacology

Insulin Restores Gestational Diabetes Mellitus-Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium

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The risk of caesarean section in obese women analysed by parity

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The life cycle of human equilibrative nucleoside transporter 1: From ER export to degradation

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An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism

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Improvement effect on endothelial function in patients with congestive heart failure treated with cardiac resynchronization therapy

(2011) Koji Enomoto et al.   Journal of Cardiology

Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation

(2011) Marcelo González et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fatty Acid Binding Protein 4 Regulates Intracellular Lipid Accumulation in Human Trophoblasts

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Placental Vascular Dysfunction in Diabetic Pregnancies: Intimations of Fetal Cardiovascular Disease?

(2011) LOPA LEACH   MICROCIRCULATION

Crossing Borders: Linking Environmental and Genetic Developmental Factors

(2011) JAAP A. JOLES   MICROCIRCULATION

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Lipid parameters for measuring risk of cardiovascular disease

(2011) Benoit J. Arsenault et al.   Nature Reviews Cardiology

Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes

(2011) L. Sobrevia et al.   PLACENTA

Placental structure and inflammation in pregnancies associated with obesity

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Review: Transport of maternal cholesterol to the fetal circulation

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Human Primary Adipocytes Exhibit Immune Cell Function: Adipocytes Prime Inflammation Independent of Macrophages

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Maternal serum triglycerides as predictive factors for large-for-gestational age newborns in women with gestational diabetes mellitus

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Longitudinal Study of Prepregnancy Cardiometabolic Risk Factors and Subsequent Risk of Gestational Diabetes Mellitus: The CARDIA Study

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Fetal exposure to gestational diabetes contributes to subsequent adult metabolic syndrome

(2010) Thomas R. Moore   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Chronic Exposure to a High-Fat Diet Induces Hepatic Steatosis, Impairs Nitric Oxide Bioavailability, and Modifies the Mitochondrial Proteome in Mice

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OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling

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Disturbances in lipid metabolism in diabetic pregnancy – Are these the cause of the problem?

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Nifedipine prevents vascular endothelial dysfunction in a mouse model of obesity and type 2 diabetes, by improving eNOS dysfunction and dephosphorylation

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Insulin resistance in obesity and metabolic syndrome: Is there a connection with platelet l-arginine transport?

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High glucose, nitric oxide, and adenosine: a vicious circle in chronic hyperglycaemia?

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Association of Maternal Weight Gain in Pregnancy With Offspring Obesity and Metabolic and Vascular Traits in Childhood

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Heart Disease and Stroke Statistics—2011 Update

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Diagnosis and Classification of Diabetes Mellitus

(2010)   DIABETES CARE

Effect of Treatment of Gestational Diabetes Mellitus on Obesity in the Next Generation

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Following in mother’s footsteps? Mother-daughter risks for insulin resistance and cardiovascular disease 15 years after gestational diabetes

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Pulse wave velocity and augmentation index, but not intima-media thickness, are early indicators of vascular damage in hypercholesterolemic children

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Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice

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Conséquences à long terme d’une exposition fœtale au diabète gestationnel

(2010) A. Burguet   JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION

Hypercholesterolemia and microvascular dysfunction: interventional strategies

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The fetal and maternal consequences of gestational diabetes mellitus

(2010) E. Albert Reece   Journal of Maternal-Fetal & Neonatal Medicine

The Developmental Origins, Mechanisms, and Implications of Metabolic Syndrome

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The Metabolic Syndrome and Cardiovascular Risk

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Endothelial dysfunction as a potential contributor in diabetic nephropathy

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Maternal Gestational Weight Gain and Offspring Weight in Adolescence

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Review: The Placenta is a Programming Agent for Cardiovascular Disease

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Review: Reactive oxygen and nitrogen species and functional adaptation of the placenta

(2010) L. Myatt   PLACENTA

Placental Amino Acid Transport and Placental Leptin Resistance in Pregnancies Complicated by Maternal Obesity☆

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Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta

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Obesity and the placenta: A consideration of nutrient exchange mechanisms in relation to aberrant fetal growth

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Low-Grade, Systemic Inflammation in Adolescents: Association With Early-Life Factors, Gender, and Lifestyle

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Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitus

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Adenosine: An Old Drug Newly Discovered

(2009) Holger K. Eltzschig   ANESTHESIOLOGY

Disrupted plasma membrane localization and loss of function reveal regions of human equilibrative nucleoside transporter 1 involved in structural integrity and activity

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Endothelium-dependent contractions and endothelial dysfunction in human hypertension

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Recent advances in arginine metabolism: roles and regulation of the arginases

(2009) Sidney M Morris Jr   BRITISH JOURNAL OF PHARMACOLOGY

Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP–C/EBPα in human umbilical vein endothelial cells from gestational diabetes

(2009) Marcelo Farías et al.   CARDIOVASCULAR RESEARCH

Associations of Gestational Weight Gain With Offspring Body Mass Index and Blood Pressure at 21 Years of Age

(2009) Abdullah A. Mamun et al.   CIRCULATION

Human Endothelial Cells of the Placental Barrier Efficiently Deliver Cholesterol to the Fetal Circulation via ABCA1 and ABCG1

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Pregnancy in women suffering from familial hypercholesterolemia: a harmful period for both mother and newborn?

(2009) Hans J Avis et al.   CURRENT OPINION IN LIPIDOLOGY

A Role for Insulin on L-Arginine Transport in Fetal Endothelial Dysfunction in Hyperglycaemia

(2009) Luis Sobrevia et al.   Current Vascular Pharmacology

Equilibrative Nucleoside Transporters in Fetal Endothelial Dysfunction in Diabetes Mellitus and Hyperglycaemia

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Insulin Action on the Human Placental Endothelium in Normal and Diabetic Pregnancy

(2009) Ursula Hiden et al.   Current Vascular Pharmacology

Fetuses of Obese Mothers Develop Insulin Resistance in Utero

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Gestational weight gain in relation to offspring body mass index and obesity from infancy through adulthood

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Homocysteine transport by systems L, A and y+L across the microvillous plasma membrane of human placenta

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Leptin Affects System A Amino Acid Transport Activity in the Human Placenta: Evidence for STAT3 Dependent Mechanisms

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Novel Pathogenic Insights in the Primary Prevention of Cardiovascular Disease

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Pregnancy-induced Hyperlipoproteinemia: Review of the Literature

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Influence of Maternal Dysmetabolic Conditions During Pregnancy on Cardiovascular Disease

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Intrauterine Exposure to Gestational Diabetes, Child Adiposity, and Blood Pressure

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Vascular Inflammation, Insulin Resistance, and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance

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Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term

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Endothelial Arginase II

(2008) Sungwoo Ryoo et al.   CIRCULATION RESEARCH

Maternal Lipids as Strong Determinants of Fetal Environment and Growth in Pregnancies With Gestational Diabetes Mellitus

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Corrigendum to “Detrimental effect of oxidized LDL on endothelial arginine metabolism and transportation” [Int. J. Biochem. Cell Biol. 40 (5) (2008) 920–928]

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Obesity and diabetes: A recipe for obstetric complications

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Intrauterine Risk Factors for Precocious Atherosclerosis

(2008) M. R. Skilton   PEDIATRICS

Human Equilibrative Nucleoside Transporters 1 and 2 may be Differentially Modulated by A2B Adenosine Receptors in Placenta Microvascular Endothelial Cells from Pre-eclampsia

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A Hypothesis for Preeclampsia: Adenosine and Inducible Nitric Oxide Synthase in Human Placental Microvascular Endothelium

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Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

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Obesity, gestational diabetes and pregnancy outcome

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Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity

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Impact of maternal circulating cholesterol and gestational diabetes mellitus on lipid metabolism in human term placenta

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The discovery of nitric oxide and its role in vascular biology

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