Z-Ligustilide inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation

Effects of natural phytochemicals inAngelica sinensis(Danggui) on Nrf2-mediated gene expression of phase II drug metabolizing enzymes and anti-inflammation

(2013) Constance Lay Lay Saw et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Z-ligustilide activates the Nrf2/HO-1 pathway and protects against cerebral ischemia–reperfusion injury in vivo and in vitro

(2013) Bin Peng et al.   BRAIN RESEARCH

Redox activation of Nrf2 & NF-κB: A double end sword?

(2013) Mabel Buelna-Chontal et al.   CELLULAR SIGNALLING

Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway

(2013) Ai-Mei Gao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Role of the aryl hydrocarbon receptor in tobacco smoke extract-induced matrix metalloproteinase-1 expression

(2013) Yuko Ono et al.   EXPERIMENTAL DERMATOLOGY

Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-κB signaling pathway

(2013) K.J. Senthil Kumar et al.   FOOD AND CHEMICAL TOXICOLOGY

Eupatolide Inhibits PDGF-induced Proliferation and Migration of Aortic Smooth Muscle Cells Through ROS-dependent Heme Oxygenase-1 Induction

(2013) Namho Kim et al.   PHYTOTHERAPY RESEARCH

Posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by methylmercury in HepG2 cells: A role of heme oxygenase-1

(2013) Issa E.A. Amara et al.   TOXICOLOGY LETTERS

Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I)

(2012) Christine Götz et al.   EXPERIMENTAL DERMATOLOGY

EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes

(2012) Sung Gu Han et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells

(2012) Alessandra Pecorelli et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival

(2011) Xiao-Ming Liu et al.   BIOCHEMICAL PHARMACOLOGY

Interaction of a functionalized complex of the flavonoid hesperetin with the AhR pathway and CYP1A1 expression: involvement in its protective effects against benzo[a]pyrene-induced oxidative stress in human skin

(2011) Antonietta Melchini et al.   CELL BIOLOGY AND TOXICOLOGY

Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect

(2011) Gaku Tsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Potential roles of PI3K/Akt and Nrf2–Keap1 pathways in regulating hormesis of Z-ligustilide in PC12 cells against oxygen and glucose deprivation

(2011) Hongyi Qi et al.   NEUROPHARMACOLOGY

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Activation of NRF2 by Nitrosative Agents and H2O2Involves KEAP1 Disulfide Formation

(2010) Simon Fourquet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exposure of human skin to benzo[a]pyrene: Role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation

(2010) C. Costa et al.   TOXICOLOGY

The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2

(2010) Jonathan Maher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia

(2009) Ju-Young Kim et al.   CARDIOVASCULAR RESEARCH

Evaluation of Oxygen Radical Absorbance Capacity in Kampo Medicine

(2009) Ko Nishimura et al.   Evidence-based Complementary and Alternative Medicine

Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease

(2009) Danielle Morse et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antagonism of Aryl Hydrocarbon Receptor Signaling by 6,2',4'-Trimethoxyflavone

(2009) I. A. Murray et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Curcumin attenuates cytochrome P450 induction in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by ROS-dependently degrading AhR and ARNT

(2008) Hyunsung Choi et al.   CANCER SCIENCE

Angelica sinensisand Its Alkylphthalides Induce the Detoxification Enzyme NAD(P)H: Quinone Oxidoreductase 1 by Alkylating Keap1

(2008) Birgit M. Dietz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay

(2007) Yoshiaki Amakura et al.   PHYTOCHEMISTRY