Human hypertrophic and keloid scar models: principles, limitations and future challenges from a tissue engineering perspective

Development, validation and testing of a human tissue engineered hypertrophic scar model

(2014) Leonarda van den Broek   ALTEX-Alternatives to Animal Experimentation

Chondroitinase injection improves keloid pathology by reorganizing the extracellular matrix with regenerated elastic fibers

(2013) Toshihiro Ishiko et al.   JOURNAL OF DERMATOLOGY

Pathological niche environment transforms dermal stem cells to keloid stem cells: A hypothesis of keloid formation and development

(2013) Miao Qu et al.   MEDICAL HYPOTHESES

Through Gap Junction Communications, Co-Cultured Mast Cells and Fibroblasts Generate Fibroblast Activities Allied with Hypertrophic Scarring

(2013) Theodore T. Foley et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Keloid-derived keratinocytes exhibit an abnormal gene expression profile consistent with a distinct causal role in keloid pathology

(2013) Jennifer M. Hahn et al.   WOUND REPAIR AND REGENERATION

Models of Abnormal Scarring

(2013) Bommie F. Seo et al.   Biomed Research International

Identification of fibrocytes from mesenchymal stem cells in keloid tissue: a potential source of abnormal fibroblasts in keloid scarring

(2012) S. A. Iqbal et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Optimum scratch assay condition to evaluate connective tissue growth factor expression for anti-scar therapy

(2012) Heekyung Moon et al.   ARCHIVES OF PHARMACAL RESEARCH

Extract ofAneilema keisakinhibits transforming growth factor-β-dependent signalling by inducing Smad2 downregulation in keloid fibroblasts

(2012) Won-Serk Kim et al.   EXPERIMENTAL DERMATOLOGY

Long-term organ culture of keloid disease tissue

(2012) Rania Bagabir et al.   EXPERIMENTAL DERMATOLOGY

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar

(2012) Moein Momtazi et al.   WOUND REPAIR AND REGENERATION

Increased in vitro differentiation of fibrocytes from keloid patients is inhibited by serum amyloid P

(2012) Michelle C. Naylor et al.   WOUND REPAIR AND REGENERATION

Wound-Associated Skin Fibrosis: Mechanisms and Treatments Based on Modulating the Inflammatory Response

(2012) Tanya J. Shaw et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Macrophages in skin injury and repair

(2011) Babak Mahdavian Delavary et al.   IMMUNOBIOLOGY

Unknown

(2011) Gerd Gauglitz et al.   MOLECULAR MEDICINE

A living system on a chip

(2011) Monya Baker   NATURE

Perioperative Conditions Affect Long-term Hypertrophic Scar Formation

(2010) Willem M. van der Veer et al.   ANNALS OF PLASTIC SURGERY

Differential distribution of haematopoietic and nonhaematopoietic progenitor cells in intralesional and extralesional keloid: do keloid scars provide a niche for nonhaematopoietic mesenchymal stem cells?

(2010) S.A. Iqbal et al.   BRITISH JOURNAL OF DERMATOLOGY

Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids

(2010) Wei-Ting Liao et al.   EXPERIMENTAL DERMATOLOGY

Immunological substance testing on human lymphatic micro-organoids in vitro

(2010) Christoph Giese et al.   JOURNAL OF BIOTECHNOLOGY

The Role of R-Spondin2 in Keratinocyte Proliferation and Epidermal Thickening in Keloid Scarring

(2010) Alvin W.C. Chua et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Cell Talk

(2010) Soad Ali Shaker et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Is There an Ideal Animal Model to Study Hypertrophic Scarring?

(2009) Maria Luiza Christovão Ramos et al.   Journal of Burn Care & Research

Chemokine-Mediated Migration of Skin-Derived Stem Cells: Predominant Role for CCL5/RANTES

(2009) Kim L. Kroeze et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tumor-Like Stem Cells Derived from Human Keloid Are Governed by the Inflammatory Niche Driven by IL-17/IL-6 Axis

(2009) Qunzhou Zhang et al.   PLoS One

Use of organotypic coculture to study keloid biology

(2008) Paris D. Butler et al.   AMERICAN JOURNAL OF SURGERY

Potential cellular and molecular causes of hypertrophic scar formation

(2008) Willem M. van der Veer et al.   BURNS

Keloids and Hypertrophic Scars: Are They Two Different Sides of the Same Coin?

(2008) OSMAN KÖSE et al.   DERMATOLOGIC SURGERY

Keratinocyte-Conditioned Media Regulate Collagen Expression in Dermal Fibroblasts

(2008) Abdi Ghaffari et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cytokine Profiling and Stat3 Phosphorylation in Epithelial–Mesenchymal Interactions between Keloid Keratinocytes and Fibroblasts

(2008) Cheh P. Lim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Current Progress in Keloid Research and Treatment

(2008) Paris D. Butler et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Isolation and Characterization of Multipotent Human Keloid-Derived Mesenchymal-Like Stem Cells

(2008) Jai-Hee Moon et al.   STEM CELLS AND DEVELOPMENT

PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing

(2008) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION