Evidence for pathogenicity of autoreactive T cells in autoimmune bullous diseases shown by animal disease models

Novel System Evaluating In Vivo Pathogenicity of Desmoglein 3-Reactive T Cell Clones Using Murine Pemphigus Vulgaris

(2014) H. Takahashi et al.   JOURNAL OF IMMUNOLOGY

Transcutaneous Gene Gun Delivery of hNC16A Induces BPAG2-Specific Tolerance

(2012) Monika Ettinger et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets

(2011) M. Kasperkiewicz et al.   BLOOD

Noncollagenous 16A domain of type XVII collagen-reactive CD4+ T cells play a pivotal role in the development of active disease in experimental bullous pemphigoid model

(2011) Hideyuki Ujiie et al.   CLINICAL IMMUNOLOGY

Pathogenesis of Bullous Pemphigoid

(2011) Hideyuki Ujiie et al.   DERMATOLOGIC CLINICS

Lesional Th17 cells and regulatory T cells in bullous pemphigoid

(2011) Masataka Arakawa et al.   EXPERIMENTAL DERMATOLOGY

Antigen-independent development of Foxp3+ regulatory T cells suppressing autoantibody production in experimental pemphigus vulgaris

(2011) T. Yokoyama et al.   INTERNATIONAL IMMUNOLOGY

Complement-Fixing Anti-Type VII Collagen Antibodies Are Induced in Th1-Polarized Lymph Nodes of Epidermolysis Bullosa Acquisita-Susceptible Mice

(2011) Christoph M. Hammers et al.   JOURNAL OF IMMUNOLOGY

Repetitive Immunization Breaks Tolerance to Type XVII Collagen and Leads to Bullous Pemphigoid in Mice

(2011) M. Hirose et al.   JOURNAL OF IMMUNOLOGY

Black Patients of African Descent and HLA-DRB1*15:03 Frequency Overrepresented in Epidermolysis Bullosa Acquisita

(2011) Coralie Zumelzu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Demonstration of Epitope-Spreading Phenomena in Bullous Pemphigoid: Results of a Prospective Multicenter Study

(2011) Giovanni Di Zenzo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Antibody-based therapeutics to watch in 2011

(2011) Janice M. Reichert   mAbs

T and B cells target identical regions of the non-collagenous domain 1 of type VII collagen in epidermolysis bullosa acquisita

(2010) Ralf Müller et al.   CLINICAL IMMUNOLOGY

What’s new in bullous pemphigoid

(2010) Hideyuki UJIIE et al.   JOURNAL OF DERMATOLOGY

Immune dysregulation of pemphigus in humans and mice

(2010) Tomoaki YOKOYAMA et al.   JOURNAL OF DERMATOLOGY

Human IgG1 Monoclonal Antibody against Human Collagen 17 Noncollagenous 16A Domain Induces Blisters via Complement Activation in Experimental Bullous Pemphigoid Model

(2010) Q. Li et al.   JOURNAL OF IMMUNOLOGY

A Novel Active Mouse Model for Bullous Pemphigoid Targeting Humanized Pathogenic Antigen

(2010) Hideyuki Ujiie et al.   JOURNAL OF IMMUNOLOGY

Generation of Antibodies of Distinct Subclasses and Specificity Is Linked to H2s in an Active Mouse Model of Epidermolysis Bullosa Acquisita

(2010) Ralf J. Ludwig et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Control systems and decision making for antibody production

(2010) Christopher C Goodnow et al.   NATURE IMMUNOLOGY

Blockade of Autoantibody-Initiated Tissue Damage by Using Recombinant Fab Antibody Fragments against Pathogenic Autoantigen

(2009) Gang Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

A Novel Humanized Neonatal Autoimmune Blistering Skin Disease Model Induced by Maternally Transferred Antibodies

(2009) W. Nishie et al.   JOURNAL OF IMMUNOLOGY

T Cells Are Required for the Production of Blister-Inducing Autoantibodies in Experimental Epidermolysis Bullosa Acquisita

(2009) A. G. Sitaru et al.   JOURNAL OF IMMUNOLOGY

Pemphigus Vulgaris in White Europeans Is Linked with HLA Class II Allele HLA DRB1*1454 but Not DRB1*1401

(2009) Monika Saha et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD40 and autoimmunity: The dark side of a great activator

(2009) Anna L. Peters et al.   SEMINARS IN IMMUNOLOGY

Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice

(2008) Kevin S. Goudy et al.   CLINICAL IMMUNOLOGY

Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid

(2008) Giovanni Di Zenzo et al.   CLINICAL IMMUNOLOGY

Pemphigus mouse model as a tool to evaluate various immunosuppressive therapies

(2008) Yujiro Takae et al.   EXPERIMENTAL DERMATOLOGY

Subepidermal blistering induced by human autoantibodies to BP180 requires innate immune players in a humanized bullous pemphigoid mouse model

(2008) Zhi Liu et al.   JOURNAL OF AUTOIMMUNITY

Transient Anti-CD40L Co-Stimulation Blockade Prevents Immune Responses against Human Bullous Pemphigoid Antigen 2: Implications for Gene Therapy

(2008) Christoph M. Lanschuetzer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY