A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening

Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment

(2015) Eddy Pasquier et al.   Oncotarget

Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment

(2015) Navjotsingh Pabla et al.   Oncotarget

Squalene Selectively Protects Mouse Bone Marrow Progenitors Against Cisplatin and Carboplatin-Induced Cytotoxicity In Vivo Without Protecting Tumor Growth

(2015) Bikul Das et al.   NEOPLASIA

Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity

(2013) L. Schyschka et al.   ARCHIVES OF TOXICOLOGY

The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines

(2013) Daisuke Fujiwara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Engineering Challenges for Instrumenting and Controlling Integrated Organ-on-Chip Systems

(2013) J. P. Wikswo et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

(2013) Kyung-Jin Jang et al.   Integrative Biology

Scaling and systems biology for integrating multiple organs-on-a-chip

(2013) John P. Wikswo et al.   LAB ON A CHIP

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

It takes nerves to recover from chemotherapy

(2013) Jean-Pierre Levesque et al.   NATURE MEDICINE

Cardiovascular Toxicities of Cancer Chemotherapy

(2013) Raphael Bonita et al.   SEMINARS IN ONCOLOGY

In Vitro Perfused Human Capillary Networks

(2013) Monica L. Moya et al.   TISSUE ENGINEERING PART C-METHODS

Cardiac Toxicity of Anticancer Agents

(2013) Alessandro Colombo et al.   Current Cardiology Reports

A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro

(2012) Kristin M. French et al.   Acta Biomaterialia

Therapeutic potential of nitric oxide donors in the prevention and treatment of angiogenesis-inhibitor-induced hypertension

(2012) Peter Kruzliak et al.   ANGIOGENESIS

Male Fertility-Implications of Anticancer Treatment and Strategies to Mitigate Gonadotoxicity

(2012) Ahmed Ragheb et al.   Anti-Cancer Agents in Medicinal Chemistry

Chemotherapy and fertility

(2012) Zeev Blumenfeld   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast

(2012) Sophie Doublier et al.   BMC CANCER

p53 Inhibits Angiogenesis by Inducing the Production of Arresten

(2012) S. Assadian et al.   CANCER RESEARCH

Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer

(2012) Kenny Chitcholtan et al.   EXPERIMENTAL CELL RESEARCH

Constructing Three-Dimensional Models to Study Mammary Gland Branching Morphogenesis and Functional Differentiation

(2012) Alvin T. Lo et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Full range physiological mass transport control in 3D tissue cultures

(2012) Yu-Hsiang Hsu et al.   LAB ON A CHIP

Interstitial Fluid and Lymph Formation and Transport: Physiological Regulation and Roles in Inflammation and Cancer

(2012) Helge Wiig et al.   PHYSIOLOGICAL REVIEWS

Palette of fluorinated voltage-sensitive hemicyanine dyes

(2012) P. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive response of vascular endothelial cells to an acute increase in shear stress magnitude

(2011) Ji Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chemotherapy-Induced Weakness and Fatigue in Skeletal Muscle: The Role of Oxidative Stress

(2011) Laura A.A. Gilliam et al.   ANTIOXIDANTS & REDOX SIGNALING

Microfluidic array for three-dimensional perfusion culture of human mammary epithelial cells

(2011) Shin-Yi Cindy Chen et al.   BIOMEDICAL MICRODEVICES

Continuously perfused microbubble array for 3D tumor spheroid model

(2011) Sivaprakash Agastin et al.   Biomicrofluidics

Biomarkers of regimen-related mucosal injury

(2011) Rachel J. Gibson et al.   CANCER TREATMENT REVIEWS

Chemotherapy-induced peripheral neurotoxicity (CIPN): An update

(2011) Andreas A. Argyriou et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Prophylactic and therapeutic strategies in chemotherapy-induced neutropenia

(2011) Emmanouil Saloustros et al.   EXPERT OPINION ON PHARMACOTHERAPY

Cardiovascular toxicity of anticancer-targeted therapy: emerging issues in the era of cardio-oncology

(2011) Emanuel Raschi et al.   Internal and Emergency Medicine

Nutrition Modulation of Gastrointestinal Toxicity Related to Cancer Chemotherapy

(2011) Hongyu Xue et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

In Vitro Blood–Brain Barrier Models: Current and Perspective Technologies

(2011) Pooja Naik et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Macrophages limit chemotherapy

(2011) Michele De Palma et al.   NATURE

Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells

(2011) Günter Glassmeier et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

Calcium Handling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes

(2011) Ilanit Itzhaki et al.   PLoS One

Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue

(2011) C. Stringari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity of Anticancer Agents in a Three-Dimensional Cell Culture Model

(2010) Victor Sanjit Nirmalanandhan et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

3D collagen type I matrix inhibits the antimigratory effect of doxorubicin

(2010) Emilie Millerot-Serrurot et al.   Cancer Cell International

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells

(2010) Jiaoya Xi et al.   FASEB JOURNAL

Cardiac side-effects of cancer chemotherapy

(2010) Jean-Jacques Monsuez et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Muscles and their myokines

(2010) B. K. Pedersen   JOURNAL OF EXPERIMENTAL BIOLOGY

Analysis of the mass transfers in an artificial kidney microchip

(2010) Aissa Ould-Dris et al.   JOURNAL OF MEMBRANE SCIENCE

Cardiotoxicity of anticancer treatments: what the cardiologist needs to know

(2010) Michael S. Ewer et al.   Nature Reviews Cardiology

Chemotherapy-induced peripheral neurotoxicity

(2010) Guido Cavaletti et al.   Nature Reviews Neurology

Airway Epithelium Stimulates Smooth Muscle Proliferation

(2009) Nikita K. Malavia et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells

(2009) Lisa A. Gurski et al.   BIOMATERIALS

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

(2009) Britta Weigelt et al.   BREAST CANCER RESEARCH AND TREATMENT

Direct effects of doxorubicin on skeletal muscle contribute to fatigue

(2009) K van Norren et al.   BRITISH JOURNAL OF CANCER

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

HERG1 gene expression as a specific tumor marker in colorectal tissues

(2009) J.H. Dolderer et al.   EJSO

Cardiovascular Complications of Cancer Therapy

(2009) Edward T.H. Yeh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cardiotoxicity of Anticancer Drugs: The Need for Cardio-Oncology and Cardio-Oncological Prevention

(2009) Adriana Albini et al.   JNCI-Journal of the National Cancer Institute

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy

(2009) Emanuel Raschi et al.   PHARMACOLOGY & THERAPEUTICS

Rapid Anastomosis of Endothelial Progenitor Cell–Derived Vessels with Host Vasculature Is Promoted by a High Density of Cotransplanted Fibroblasts

(2009) Xiaofang Chen et al.   TISSUE ENGINEERING PART A

Vincristine attenuates doxorubicin cardiotoxicity

(2008) Kanu Chatterjee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1

(2008) D. H. Shin et al.   BLOOD

Targeting tumor angiogenesis with histone deacetylase inhibitors

(2008) Leigh Ellis et al.   CANCER LETTERS

Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis

(2008) María Valcárcel et al.   Journal of Translational Medicine

Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells

(2008) Ilya Serebriiskii et al.   MATRIX BIOLOGY

3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs

(2008) Jayme L. Horning et al.   MOLECULAR PHARMACEUTICS

New dimensions in tumor immunology: what does 3D culture reveal?

(2008) Chantal Feder-Mengus et al.   TRENDS IN MOLECULAR MEDICINE

Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity

(2007) Laurent David et al.   Acta Biomaterialia