A long journey to effective obesity treatments: is there light at the end of the tunnel?

Lemons for Obesity

(2013) Michael S. Lauer   ANNALS OF INTERNAL MEDICINE

Medium Chain Triglyceride Oil Consumption as Part of a Weight Loss Diet Does Not Lead to an Adverse Metabolic Profile When Compared to Olive Oil

(2013) Marie-Pierre St-Onge et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Are there still healthy obese patients?

(2013) Matthias Blüher   Current Opinion in Endocrinology Diabetes and Obesity

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

Angiopoietin-like protein 4: health effects, modulating agents and structure–function relationships

(2012) Charlotte Grootaert et al.   Expert Review of Proteomics

Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high-fat-diet-induced obesity

(2012) Julien Auffret et al.   FASEB JOURNAL

Cellular and molecular comparison of redifferentiation of intramuscular- and visceral-adipocyte derived progeny cells

(2012) Jie Chen et al.   International Journal of Biological Sciences

Piperine, a Component of Black Pepper, Inhibits Adipogenesis by Antagonizing PPARγ Activity in 3T3-L1 Cells

(2012) Ui-Hyun Park et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Increased Tenascin C And Toll-Like Receptor 4 Levels in Visceral Adipose Tissue as a Link between Inflammation and Extracellular Matrix Remodeling in Obesity

(2012) Victoria Catalán et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolically Healthy Obesity and Risk of All-Cause and Cardiovascular Disease Mortality

(2012) Mark Hamer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity pharmacotherapy: What is next?

(2012) Francheska Colon-Gonzalez et al.   MOLECULAR ASPECTS OF MEDICINE

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

What is the prognosis for new centrally-acting anti-obesity drugs?

(2012) David J. Heal et al.   NEUROPHARMACOLOGY

Metabolic Syndrome in Healthy Obese, Overweight, and Normal Weight Individuals: The Atherosclerosis Risk in Communities Study

(2012) Patrick T. Bradshaw et al.   Obesity

Randomized Placebo-Controlled Clinical Trial of Lorcaserin for Weight Loss in Type 2 Diabetes Mellitus: The BLOOM-DM Study

(2012) Patrick M. O'Neil et al.   Obesity

Agouti Revisited: Transcript Quantification of the ASIP Gene in Bovine Tissues Related to Protein Expression and Localization

(2012) Elke Albrecht et al.   PLoS One

DLK1(PREF1) is a negative regulator of adipogenesis in CD105+/CD90+/CD34+/CD31−/FABP4− adipose-derived stromal cells from subcutaneous abdominal fat pats of adult women

(2012) Maria C Mitterberger et al.   Stem Cell Research

Organismal Carbohydrate and Lipid Homeostasis

(2012) D. G. Hardie   Cold Spring Harbor Perspectives in Biology

The Effects of Capsaicin and Capsiate on Energy Balance: Critical Review and Meta-analyses of Studies in Humans

(2011) M.-J. Ludy et al.   CHEMICAL SENSES

Standards of Medical Care in Diabetes--2012

(2011)   DIABETES CARE

MicroRNA regulation in mammalian adipogenesis

(2011) Josue M Romao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Managing obesity – from childhood and onwards

(2011) Ylva Trolle Lagerros et al.   International Journal of Pediatric Obesity

Transplantation of mature adipocyte-derived dedifferentiated fat (DFAT) cells improves urethral sphincter contractility in a rat model

(2011) Daisuke Obinata et al.   INTERNATIONAL JOURNAL OF UROLOGY

Relative Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Tumor Necrosis Factor-α (TNF-α)-induced Lipolysis in Adipocytes

(2011) Xingyuan Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subcutaneous Adipose Tissue Remodeling during the Initial Phase of Weight Gain Induced by Overfeeding in Humans

(2011) M. Alligier et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Controlled-Release Phentermine/Topiramate in Severely Obese Adults: A Randomized Controlled Trial (EQUIP)

(2011) David B. Allison et al.   Obesity

Pharmacologic management of obesity

(2011) Robert F. Kushner   PEDIATRIC BLOOD & CANCER

Transplanted Hypothalamic Neurons Restore Leptin Signaling and Ameliorate Obesity in db/db Mice

(2011) A. Czupryn et al.   SCIENCE

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARγ expression

(2010) Sang Yun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases

(2010) Tsuyoshi Kadomatsu et al.   FEBS Journal

Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance

(2010) Miriam E. Clegg   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Combined amylin–leptin treatment lowers blood pressure and adiposity in lean and obese rats

(2010) R Seth et al.   INTERNATIONAL JOURNAL OF OBESITY

The effect of ractopamine hydrochloride on gene expression in adipose tissues of finishing pigs1

(2010) C. H. C. Halsey et al.   JOURNAL OF ANIMAL SCIENCE

Eicosapentaenoic Acid Prevents and Reverses Insulin Resistance in High-Fat Diet-Induced Obese Mice via Modulation of Adipose Tissue Inflammation

(2010) Nishan S. Kalupahana et al.   JOURNAL OF NUTRITION

Medical Therapy for Obesity

(2010) George A. Bray   MOUNT SINAI JOURNAL OF MEDICINE

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

(2010) Steven R. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene expression in hypothalamus, liver, and adipose tissues and food intake response to melanocortin-4 receptor agonist in pigs expressing melanocortin-4 receptor mutations

(2010) C. Richard Barb et al.   PHYSIOLOGICAL GENOMICS

Secreted proteins from adipose tissue and skeletal muscle – adipokines, myokines and adipose/muscle cross-talk

(2010) Paul Trayhurn et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Leptin at 14 y of age: an ongoing story

(2009) Jeffrey M Friedman   AMERICAN JOURNAL OF CLINICAL NUTRITION

The origin of intermuscular adipose tissue and its pathophysiological implications

(2009) Roberto Vettor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipose Overexpression of Desnutrin Promotes Fatty Acid Use and Attenuates Diet-Induced Obesity

(2009) M. Ahmadian et al.   DIABETES

The effects of Xanthigen™in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat

(2009) M. Abidov et al.   DIABETES OBESITY & METABOLISM

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

The Pattern of Growth Hormone Delivery to Peripheral Tissues Determines Insulin-Like Growth Factor-1 and Lipolytic Responses in Obese Subjects

(2009) Sowmya Surya et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation

(2009) Judith L Ngondi et al.   Lipids in Health and Disease

Minireview: Pref-1: Role in Adipogenesis and Mesenchymal Cell Fate

(2009) Hei Sook Sul   MOLECULAR ENDOCRINOLOGY

Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet

(2009) Ronald L. Prior et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Causes and control of excess body fat

(2009) Jeffrey M. Friedman   NATURE

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Microarray gene expression profiles of fasting induced changes in liver and adipose tissues of pigs expressing the melanocortin-4 receptor D298N variant

(2009) Sender Lkhagvadorj et al.   PHYSIOLOGICAL GENOMICS

Mature adipocytes may be a source of stem cells for tissue engineering

(2008) M.E. Fernyhough et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of White Adipocyte Progenitor Cells In Vivo

(2008) Matthew S. Rodeheffer et al.   CELL

Establishment of a preadipocyte cell line derived from mature adipocytes of GFP transgenic mice and formation of adipose tissue

(2008) Hiroyuki Nobusue et al.   CELL AND TISSUE RESEARCH

Progeny from Dedifferentiated Bovine Adipocytes Display Protracted Adipogenesis

(2008) Melinda E. Fernyhough et al.   CELLS TISSUES ORGANS

Leptin Regulates Peripheral Lipid Metabolism Primarily through Central Effects on Food Intake

(2008) Xavier Prieur et al.   ENDOCRINOLOGY

Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms

(2008) James L. Trevaskis et al.   ENDOCRINOLOGY

Impairment of nutritional regulation of adipose triglyceride lipase expression with age

(2008) A Caimari et al.   INTERNATIONAL JOURNAL OF OBESITY

BOARD-INVITED REVIEW: The biology and regulation of preadipocytes and adipocytes in meat animals1,2

(2008) G. J. Hausman et al.   JOURNAL OF ANIMAL SCIENCE

Increased Elongase and Desaturase Gene Expression with Stearidonic Acid Enriched Diet Does Not Enhance Long-Chain (n-3) Content of Seawater Atlantic Salmon (Salmo salar L.)

(2008) Matthew R. Miller et al.   JOURNAL OF NUTRITION

Developmental, Hormonal, and Nutritional Regulation of Porcine Adipose Triglyceride Lipase (ATGL)

(2008) Jeffrey A. Deiuliis et al.   LIPIDS

The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study

(2008) Julius E Oben et al.   Lipids in Health and Disease

Hypothalamic Malonyl-Coenzyme A and the Control of Energy Balance

(2008) Michael J. Wolfgang et al.   MOLECULAR ENDOCRINOLOGY

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE

High glucose induces adipogenic differentiation of muscle-derived stem cells

(2008) P. Aguiari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

(2008) J. D. Roth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

White Fat Progenitor Cells Reside in the Adipose Vasculature

(2008) W. Tang et al.   SCIENCE

Expression profiling analysis for genes related to meat quality and carcass traits during postnatal development of backfat in two pig breeds

(2008) MingZhou Li et al.   Science in China. Series C, Life sciences / Chinese Academy of Sciences