Utility of Ion Mobility Mass Spectrometry for Drug-to-Antibody Ratio Measurements in Antibody-Drug Conjugates

Detection of conformation types of cyclosporin retaining intramolecular hydrogen bonds by mass spectrometry

(2014) Suk-Joon Hyung et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Innovative Native MS Methodologies for Antibody Drug Conjugate Characterization: High Resolution Native MS and IM-MS for Average DAR and DAR Distribution Assessment

(2014) François Debaene et al.   ANALYTICAL CHEMISTRY

Metal-Induced Conformational Changes of Human Metallothionein-2A: A Combined Theoretical and Experimental Study of Metal-Free and Partially Metalated Intermediates

(2014) Shu-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Charge Reduction Stabilizes Intact Membrane Protein Complexes for Mass Spectrometry

(2014) Shahid Mehmood et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC: overview and applications

(2014) Mark Haverick et al.   mAbs

Approaches to Interchain Cysteine-Linked ADC Characterization by Mass Spectrometry

(2014) John F. Valliere-Douglass et al.   MOLECULAR PHARMACEUTICS

Integrative Modelling Coupled with Ion Mobility Mass Spectrometry Reveals Structural Features of the Clamp Loader in Complex with Single-Stranded DNA Binding Protein

(2013) Argyris Politis et al.   JOURNAL OF MOLECULAR BIOLOGY

Complementary MS Methods Assist Conformational Characterization of Antibodies with Altered S–S Bonding Networks

(2013) Lisa M. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Site-specific antibody drug conjugates for cancer therapy

(2013) Siler Panowski et al.   mAbs

Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion

(2013) Elsa Wagner-Rousset et al.   mAbs

SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket

(2013) Weiman Xing et al.   NATURE

Characterization of the drug-to-antibody ratio distribution for antibody–drug conjugates in plasma/serum

(2013) Keyang Xu et al.   Bioanalysis

Mitigation of signal suppression caused by the use of trifluoroacetic acid in liquid chromatography mobile phases during liquid chromatography/mass spectrometry analysis via post-column addition of ammonium hydroxide

(2012) Chang-Ching Chan et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Analytical methods for physicochemical characterization of antibody drug conjugates

(2011) Aditya Wakankar et al.   mAbs

Characterization of protein therapeutics by mass spectrometry: recent developments and future directions

(2010) Guodong Chen et al.   DRUG DISCOVERY TODAY

Molecular mass analysis of antibodies by on-line SEC-MS

(2008) Lowell J. Brady et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Ion mobility adds an additional dimension to mass spectrometric analysis of solution-phase hydrogen/deuterium exchange

(2008) Roxana E. Iacob et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY