Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model

NAT8L (N-Acetyltransferase 8-Like) Accelerates Lipid Turnover and Increases Energy Expenditure in Brown Adipocytes

(2013) Ariane R. Pessentheiner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary triheptanoin rescues oligodendrocyte loss, dysmyelination and motor function in the nur7 mouse model of Canavan disease

(2013) Jeremy S. Francis et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Astroglial Redistribution of Aquaporin 4 During Spongy Degeneration in a Canavan Disease Mouse Model

(2013) Tim Clarner et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Decreased NAA in Gray Matter is Correlated with Decreased Availability of Acetate in White Matter in Postmortem Multiple Sclerosis Cortex

(2013) S. Li et al.   NEUROCHEMICAL RESEARCH

Canavan disease, a rare early-onset human spongiform leukodystrophy: Insights into its genesis and possible clinical interventions

(2012) M.H. Baslow et al.   BIOCHIMIE

Absence of SHATI/Nat8l reduces social interaction in mice

(2012) Yoko Furukawa-Hibi et al.   NEUROSCIENCE LETTERS

Long-Term Follow-Up After Gene Therapy for Canavan Disease

(2012) P. Leone et al.   Science Translational Medicine

Endogenous aspartoacylase expression is responsive to glutamatergic activity in vitro and in vivo

(2011) Jeremy S. Francis et al.   GLIA

Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: Implications for specialized acetyl coenzyme A metabolism in the CNS

(2010) Prasanth S. Ariyannur et al.   BRAIN RESEARCH

Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia

(2009) Elsa Wiame et al.   BIOCHEMICAL JOURNAL

Nur7 Is a Nonsense Mutation in the Mouse Aspartoacylase Gene That Causes Spongy Degeneration of the CNS

(2008) M. Traka et al.   JOURNAL OF NEUROSCIENCE