RESTRICTED PLEIOTROPY FACILITATES MUTATIONAL EROSION OF MAJOR LIFE-HISTORY TRAITS

Coevolution Trumps Pleiotropy: Carbon Assimilation Traits Are Independent of Metabolic Network Structure in Budding Yeast

(2013) Dana A. Opulente et al.   PLoS One

The many faces of pleiotropy

(2012) Annalise B. Paaby et al.   TRENDS IN GENETICS

Gene dispensability

(2011) Ryszard Korona   CURRENT OPINION IN BIOTECHNOLOGY

Yeast cells can access distinct quiescent states

(2011) M. M. Klosinska et al.   GENES & DEVELOPMENT

Bugs, drugs and chemical genomics

(2011) Terry Roemer et al.   Nature Chemical Biology

The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

(2011) Günter P. Wagner et al.   NATURE REVIEWS GENETICS

Trait Variation in Yeast Is Defined by Population History

(2011) Jonas Warringer et al.   PLoS Genetics

Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program

(2010) Mikhail V Blagosklonny   CELL CYCLE

Measuring growth rate in high-throughput growth phenotyping

(2010) Anders Blomberg   CURRENT OPINION IN BIOTECHNOLOGY

FISHER'S MODEL AND THE GENOMICS OF ADAPTATION: RESTRICTED PLEIOTROPY, HETEROGENOUS MUTATION, AND PARALLEL EVOLUTION

(2010) Luis-Miguel Chevin et al.   EVOLUTION

System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae

(2010) D. Gresham et al.   GENETICS

One Hundred Years of Pleiotropy: A Retrospective

(2010) F. W. Stearns   GENETICS

Genomic patterns of pleiotropy and the evolution of complexity

(2010) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

(2010) Paola Fabrizio et al.   PLoS Genetics

A Microarray-Based Genetic Screen for Yeast Chronological Aging Factors

(2010) Mirela Matecic et al.   PLoS Genetics

LOW FREQUENCY OF MUTATIONS WITH STRONGLY DELETERIOUS BUT NONLETHAL FITNESS EFFECTS

(2009) Angelina Fudala et al.   EVOLUTION

Effect of calorie restriction on the metabolic history of chronologically aging yeast

(2009) Alexander A. Goldberg et al.   EXPERIMENTAL GERONTOLOGY

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Predicting Cellular Growth from Gene Expression Signatures

(2009) Edoardo M. Airoldi et al.   PLoS Computational Biology

Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation

(2008) Luis López-Maury et al.   NATURE REVIEWS GENETICS

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE

Global Transcriptome and Deletome Profiles of Yeast Exposed to Transition Metals

(2008) Yong Hwan Jin et al.   PLoS Genetics

Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast

(2007) Matthew J. Brauer et al.   MOLECULAR BIOLOGY OF THE CELL