Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine

Risk Factors for Breast Cancer for Women Aged 40 to 49 Years

(2013) Heidi D. Nelson   ANNALS OF INTERNAL MEDICINE

Inhibitory Effects of Onion (Allium cepa L.) Extract on Proliferation of Cancer Cells and Adipocytes via Inhibiting Fatty Acid Synthase

(2013) Yi Wang et al.   Asian Pacific Journal of Cancer Prevention

Effects of metformin on breast cancer cell proliferation, the AMPK pathway and the cell cycle

(2013) S. M. Hadad et al.   Clinical & Translational Oncology

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients

(2013) Mika Hilvo et al.   INTERNATIONAL JOURNAL OF CANCER

Alteration of fatty acid metabolism in the liver, adipose tissue, and testis of male mice conceived through assisted reproductive technologies: fatty acid metabolism in ART mice

(2013) Li-Ya Wang et al.   Lipids in Health and Disease

Circulatory Estrogen Level Protects Against Breast Cancer in Obese Women

(2013) Zsuzsanna Suba   Recent Patents on Anti-Cancer Drug Discovery

Obesity, diabetes mellitus, and the risk of female breast cancer in Eastern China

(2013) Xiao-Lei Wang et al.   World Journal of Surgical Oncology

De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

(2013) Leah Eissing et al.   Nature Communications

Mammographic Breast Density and Breast Cancer: Evidence of a Shared Genetic Basis

(2012) J. S. Varghese et al.   CANCER RESEARCH

Emerging Glycolysis Targeting and Drug Discovery from Chinese Medicine in Cancer Therapy

(2012) Zhiyu Wang et al.   Evidence-based Complementary and Alternative Medicine

Regulation of lipogenesis by cyclin-dependent kinase 8–mediated control of SREBP-1

(2012) Xiaoping Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting tumor cell metabolism with statins

(2012) J W Clendening et al.   ONCOGENE

Fatty Acid Synthase Inhibition by Amentoflavone Suppresses HER2/neu(erbB2) Oncogene in SKBR3 Human Breast Cancer Cells

(2012) Jin Sun Lee et al.   PHYTOTHERAPY RESEARCH

De Novo Lipogenesis in Adipose Tissue Is Associated with Course of Morbid Obesity after Bariatric Surgery

(2012) Lourdes Garrido-Sánchez et al.   PLoS One

Mechanisms of Gene Regulation by Fatty Acids

(2012) Anastasia Georgiadi et al.   Advances in Nutrition

Antitumor effect of orlistat, a fatty acid synthase inhibitor, is via activation of caspase-3 on human colorectal carcinoma-bearing animal

(2011) Hui-Yen Chuang et al.   BIOMEDICINE & PHARMACOTHERAPY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fatty acid synthase inhibitors from the hulls of Nephelium lappaceum L.

(2011) You-Xing Zhao et al.   CARBOHYDRATE RESEARCH

Chinese medicine approach in clinical practice for breast cancer survivors

(2011) Jie-jia Li et al.   Chinese Journal of Integrative Medicine

Genetic control ofde novolipogenesis: role in diet-induced obesity

(2010) Maggie S. Strable et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

New Perspectives on Chinese Herbal Medicine (Zhong-Yao) Research and Development

(2010) Si-Yuan Pan et al.   Evidence-based Complementary and Alternative Medicine

Fatty acid synthase as a potential therapeutic target in cancer

(2010) Richard Flavin et al.   Future Oncology

Spatholobus suberectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint

(2010) Zhi-Yu Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Liver fatty acid-binding protein and obesity

(2010) Barbara P. Atshaves et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Metabolism and proliferation share common regulatory pathways in cancer cells

(2010) V Fritz et al.   ONCOGENE

The Role of Traditional Chinese Herbal Medicines in Cancer Therapy – from TCM Theory to Mechanistic Insights

(2010) W. Hsiao et al.   PLANTA MEDICA

Lipoexpediency: de novo lipogenesis as a metabolic signal transmitter

(2010) Irfan J. Lodhi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Fatty Acid Synthase Inhibition by Amentoflavone Induces Apoptosis and Antiproliferation in Human Breast Cancer Cells

(2009) Jin Sun Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

(2009) T Mashima et al.   BRITISH JOURNAL OF CANCER

Placebo-Controlled, Double-Blind, Prospective, Randomized Study on the Effect of Octreotide LAR in the Control of Tumor Growth in Patients With Metastatic Neuroendocrine Midgut Tumors: A Report From the PROMID Study Group

(2009) Anja Rinke et al.   JOURNAL OF CLINICAL ONCOLOGY

Physical Activity, Weight Control, and Breast Cancer Risk and Survival: Clinical Trial Rationale and Design Considerations

(2009) R. Ballard-Barbash et al.   JNCI-Journal of the National Cancer Institute

A new dawn for the use of traditional Chinese medicine in cancer therapy

(2009) Harendra S Parekh et al.   Molecular Cancer

Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells

(2009) W Zhou et al.   ONCOGENE

Complementary and alternative medicine (CAM) and cancer: The kind face of complementary medicine

(2009) E. Ernst   International Journal of Surgery

Weight, height, body mass index and risk of breast cancer in postmenopausal women: a case-control study

(2008) Ali Montazeri et al.   BMC CANCER

Botanicals used in complementary and alternative medicine treatment of cancer: clinical science and future perspectives

(2008) Scott Miller et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the β-ketoacyl reductase reaction

(2008) María Jesús Vázquez et al.   FEBS Journal

Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

(2008) Ralph J Deberardinis   GENETICS IN MEDICINE

AMP-activated protein kinase and human cancer: cancer metabolism revisited

(2008) F P Kuhajda   INTERNATIONAL JOURNAL OF OBESITY

Inhibition of Coix seed extract on fatty acid synthase, a novel target for anticancer activity

(2008) Fei Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY