Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level
Authors
Keywords
Intervertebral disc mechanobiology, Spinal loads, Intradiscal pressure, Degenerative environment, Mechanotransduction
Journal
EUROPEAN SPINE JOURNAL
Volume 23, Issue S3, Pages 333-343
Publisher
Springer Nature
Online
2013-06-20
DOI
10.1007/s00586-013-2855-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Factors regulating viable cell density in the intervertebral disc: blood supply in relation to disc height
- (2013) Olga. A. Boubriak et al. JOURNAL OF ANATOMY
- Spinal loads during position changes
- (2012) A. Rohlmann et al. CLINICAL BIOMECHANICS
- Homing of Mesenchymal Stem Cells in Induced Degenerative Intervertebral Discs in a Whole Organ Culture System
- (2012) Svenja Illien-Jünger et al. SPINE
- A Musculoskeletal model for the lumbar spine
- (2011) Miguel Christophy et al. Biomechanics and Modeling in Mechanobiology
- Difference in Energy Metabolism of Annulus Fibrosus and Nucleus Pulposus Cells of the Intervertebral Disc
- (2011) Jessica Czamanski Salvatierra et al. Cellular and Molecular Bioengineering
- Cyclic stretch-induced apoptosis in rat annulus fibrosus cells is mediated in part by endoplasmic reticulum stress through nitric oxide production
- (2011) Yue-Hui Zhang et al. EUROPEAN SPINE JOURNAL
- Sagittal balance disorders in severe degenerative spine. Can we identify the compensatory mechanisms?
- (2011) Cédric Barrey et al. EUROPEAN SPINE JOURNAL
- Equilibrium of the human body and the gravity line: the basics
- (2011) J. C. Le Huec et al. EUROPEAN SPINE JOURNAL
- An improved multi-joint EMG-assisted optimization approach to estimate joint and muscle forces in a musculoskeletal model of the lumbar spine
- (2011) Denis Gagnon et al. JOURNAL OF BIOMECHANICS
- Differential response of nucleus pulposus intervertebral disc cells to high salt, sorbitol, and urea
- (2011) Eleni Mavrogonatou et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Mechanical loading affects the energy metabolism of intervertebral disc cells
- (2011) Hanan N. Fernando et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways
- (2011) Harris Pratsinis et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells
- (2011) Cornelia Neidlinger-Wilke et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Evaluation of platelet-rich plasma and hydrostatic pressure regarding cell differentiation in nucleus pulposus tissue engineering
- (2011) Antje Mietsch et al. Journal of Tissue Engineering and Regenerative Medicine
- An enhanced and validated generic thoraco-lumbar spine model for prediction of muscle forces
- (2011) Kap-Soo Han et al. MEDICAL ENGINEERING & PHYSICS
- Complex loading affects intervertebral disc mechanics and biology
- (2011) B.A. Walter et al. OSTEOARTHRITIS AND CARTILAGE
- In Vitro and in Vivo Testing of a Novel Regulatory System for Gene Therapy for Intervertebral Disc Degeneration
- (2011) Gwendolyn Sowa et al. SPINE
- Measured loads on a vertebral body replacement during sitting
- (2011) Antonius Rohlmann et al. Spine Journal
- Development of a Bioreactor for Axially Loaded Intervertebral Disc Organ Culture
- (2011) Lisbet Haglund et al. TISSUE ENGINEERING PART C-METHODS
- The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration
- (2011) Hamish TJ Gilbert et al. ARTHRITIS RESEARCH & THERAPY
- A multibody modelling approach to determine load sharing between passive elements of the lumbar spine
- (2010) Alireza Abouhossein et al. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
- Mechanical design criteria for intervertebral disc tissue engineering
- (2010) Nandan L. Nerurkar et al. JOURNAL OF BIOMECHANICS
- Influence of low glucose supply on the regulation of gene expression by nucleus pulposus cells and their responsiveness to mechanical loading
- (2010) Christina Rinkler et al. JOURNAL OF NEUROSURGERY-SPINE
- Human intervertebral disc internal strain in compression: The effect of disc region, loading position, and degeneration
- (2010) Grace D. O'Connell et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Effect of varying osmotic conditions on the response of bovine nucleus pulposus cells to growth factors and the activation of the ERK and Akt pathways
- (2010) Eleni Mavrogonatou et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Spinal muscles can create compressive follower loads in the lumbar spine in a neutral standing posture
- (2010) Kap-Soo Han et al. MEDICAL ENGINEERING & PHYSICS
- The Combined Effects of Limited Nutrition and High-Frequency Loading on Intervertebral Discs With Endplates
- (2010) Svenja Illien-Jünger et al. SPINE
- Effects of Torsion on Intervertebral Disc Gene Expression and Biomechanics, Using a Rat Tail Model
- (2010) Ana Barbir et al. SPINE
- Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs
- (2009) Jan O Gordeladze et al. ACTA PHARMACOLOGICA SINICA
- Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs
- (2009) Christine Lyn Le Maitre et al. ARTHRITIS AND RHEUMATISM
- Signaling networks and transcription factors regulating mechanotransduction in bone
- (2009) Dionysios J. Papachristou et al. BIOESSAYS
- High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response
- (2009) Eleni Mavrogonatou et al. DNA REPAIR
- Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model
- (2009) Tomokazu Nakamura et al. EUROPEAN SPINE JOURNAL
- Cellular mechanobiology of the intervertebral disc: New directions and approaches
- (2009) Adam H. Hsieh et al. JOURNAL OF BIOMECHANICS
- A comparative study of two trunk biomechanical models under symmetric and asymmetric loadings
- (2009) N. Arjmand et al. JOURNAL OF BIOMECHANICS
- In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression
- (2009) Karin Wuertz et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- The internal mechanical functioning of intervertebral discs and articular cartilage, and its relevance to matrix biology
- (2009) Michael A. Adams et al. MATRIX BIOLOGY
- Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading
- (2009) L. Ramage et al. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
- Characterization of Intervertebral Disc Aging
- (2009) Gwendolyn Sowa et al. SPINE
- Mechanical Stimulation Alters Pleiotrophin and Aggrecan Expression by Human Intervertebral Disc Cells and Influences Their Capacity to Stimulate Endothelial Cell Migration
- (2009) Cornelia Neidlinger-Wilke et al. SPINE
- 2009 ISSLS Prize Winner: Does Discography Cause Accelerated Progression of Degeneration Changes in the Lumbar Disc
- (2009) Eugene J. Carragee et al. SPINE
- Mechanotransduction in osteoblast regulation and bone disease
- (2009) Katerina K. Papachroni et al. TRENDS IN MOLECULAR MEDICINE
- Transcription factors controlling osteoblastogenesis
- (2008) Pierre J. Marie ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Loads on a telemeterized vertebral body replacement measured in three patients within the first postoperative month
- (2008) Antonius Rohlmann et al. CLINICAL BIOMECHANICS
- Growth Factors in Intervertebral Disc Homeostasis
- (2008) Harris Pratsinis et al. CONNECTIVE TISSUE RESEARCH
- Intervertebral disc cell response to dynamic compression is age and frequency dependent
- (2008) Casey L. Korecki et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Dynamic Compression Effects on Intervertebral Disc Mechanics and Biology
- (2008) Casey L. Korecki et al. SPINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started