Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level

Factors regulating viable cell density in the intervertebral disc: blood supply in relation to disc height

(2013) Olga. A. Boubriak et al.   JOURNAL OF ANATOMY

Spinal loads during position changes

(2012) A. Rohlmann et al.   CLINICAL BIOMECHANICS

Homing of Mesenchymal Stem Cells in Induced Degenerative Intervertebral Discs in a Whole Organ Culture System

(2012) Svenja Illien-Jünger et al.   SPINE

A Musculoskeletal model for the lumbar spine

(2011) Miguel Christophy et al.   Biomechanics and Modeling in Mechanobiology

Difference in Energy Metabolism of Annulus Fibrosus and Nucleus Pulposus Cells of the Intervertebral Disc

(2011) Jessica Czamanski Salvatierra et al.   Cellular and Molecular Bioengineering

Cyclic stretch-induced apoptosis in rat annulus fibrosus cells is mediated in part by endoplasmic reticulum stress through nitric oxide production

(2011) Yue-Hui Zhang et al.   EUROPEAN SPINE JOURNAL

Sagittal balance disorders in severe degenerative spine. Can we identify the compensatory mechanisms?

(2011) Cédric Barrey et al.   EUROPEAN SPINE JOURNAL

Equilibrium of the human body and the gravity line: the basics

(2011) J. C. Le Huec et al.   EUROPEAN SPINE JOURNAL

An improved multi-joint EMG-assisted optimization approach to estimate joint and muscle forces in a musculoskeletal model of the lumbar spine

(2011) Denis Gagnon et al.   JOURNAL OF BIOMECHANICS

Differential response of nucleus pulposus intervertebral disc cells to high salt, sorbitol, and urea

(2011) Eleni Mavrogonatou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanical loading affects the energy metabolism of intervertebral disc cells

(2011) Hanan N. Fernando et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways

(2011) Harris Pratsinis et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells

(2011) Cornelia Neidlinger-Wilke et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Evaluation of platelet-rich plasma and hydrostatic pressure regarding cell differentiation in nucleus pulposus tissue engineering

(2011) Antje Mietsch et al.   Journal of Tissue Engineering and Regenerative Medicine

An enhanced and validated generic thoraco-lumbar spine model for prediction of muscle forces

(2011) Kap-Soo Han et al.   MEDICAL ENGINEERING & PHYSICS

Complex loading affects intervertebral disc mechanics and biology

(2011) B.A. Walter et al.   OSTEOARTHRITIS AND CARTILAGE

In Vitro and in Vivo Testing of a Novel Regulatory System for Gene Therapy for Intervertebral Disc Degeneration

(2011) Gwendolyn Sowa et al.   SPINE

Measured loads on a vertebral body replacement during sitting

(2011) Antonius Rohlmann et al.   Spine Journal

Development of a Bioreactor for Axially Loaded Intervertebral Disc Organ Culture

(2011) Lisbet Haglund et al.   TISSUE ENGINEERING PART C-METHODS

The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration

(2011) Hamish TJ Gilbert et al.   ARTHRITIS RESEARCH & THERAPY

A multibody modelling approach to determine load sharing between passive elements of the lumbar spine

(2010) Alireza Abouhossein et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Mechanical design criteria for intervertebral disc tissue engineering

(2010) Nandan L. Nerurkar et al.   JOURNAL OF BIOMECHANICS

Influence of low glucose supply on the regulation of gene expression by nucleus pulposus cells and their responsiveness to mechanical loading

(2010) Christina Rinkler et al.   JOURNAL OF NEUROSURGERY-SPINE

Human intervertebral disc internal strain in compression: The effect of disc region, loading position, and degeneration

(2010) Grace D. O'Connell et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effect of varying osmotic conditions on the response of bovine nucleus pulposus cells to growth factors and the activation of the ERK and Akt pathways

(2010) Eleni Mavrogonatou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Spinal muscles can create compressive follower loads in the lumbar spine in a neutral standing posture

(2010) Kap-Soo Han et al.   MEDICAL ENGINEERING & PHYSICS

The Combined Effects of Limited Nutrition and High-Frequency Loading on Intervertebral Discs With Endplates

(2010) Svenja Illien-Jünger et al.   SPINE

Effects of Torsion on Intervertebral Disc Gene Expression and Biomechanics, Using a Rat Tail Model

(2010) Ana Barbir et al.   SPINE

Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs

(2009) Jan O Gordeladze et al.   ACTA PHARMACOLOGICA SINICA

Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs

(2009) Christine Lyn Le Maitre et al.   ARTHRITIS AND RHEUMATISM

Signaling networks and transcription factors regulating mechanotransduction in bone

(2009) Dionysios J. Papachristou et al.   BIOESSAYS

High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response

(2009) Eleni Mavrogonatou et al.   DNA REPAIR

Effects of compressive loading on biomechanical properties of disc and peripheral tissue in a rat tail model

(2009) Tomokazu Nakamura et al.   EUROPEAN SPINE JOURNAL

Cellular mechanobiology of the intervertebral disc: New directions and approaches

(2009) Adam H. Hsieh et al.   JOURNAL OF BIOMECHANICS

A comparative study of two trunk biomechanical models under symmetric and asymmetric loadings

(2009) N. Arjmand et al.   JOURNAL OF BIOMECHANICS

In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression

(2009) Karin Wuertz et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The internal mechanical functioning of intervertebral discs and articular cartilage, and its relevance to matrix biology

(2009) Michael A. Adams et al.   MATRIX BIOLOGY

Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading

(2009) L. Ramage et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Characterization of Intervertebral Disc Aging

(2009) Gwendolyn Sowa et al.   SPINE

Mechanical Stimulation Alters Pleiotrophin and Aggrecan Expression by Human Intervertebral Disc Cells and Influences Their Capacity to Stimulate Endothelial Cell Migration

(2009) Cornelia Neidlinger-Wilke et al.   SPINE

2009 ISSLS Prize Winner: Does Discography Cause Accelerated Progression of Degeneration Changes in the Lumbar Disc

(2009) Eugene J. Carragee et al.   SPINE

Mechanotransduction in osteoblast regulation and bone disease

(2009) Katerina K. Papachroni et al.   TRENDS IN MOLECULAR MEDICINE

Transcription factors controlling osteoblastogenesis

(2008) Pierre J. Marie   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Loads on a telemeterized vertebral body replacement measured in three patients within the first postoperative month

(2008) Antonius Rohlmann et al.   CLINICAL BIOMECHANICS

Growth Factors in Intervertebral Disc Homeostasis

(2008) Harris Pratsinis et al.   CONNECTIVE TISSUE RESEARCH

Intervertebral disc cell response to dynamic compression is age and frequency dependent

(2008) Casey L. Korecki et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Dynamic Compression Effects on Intervertebral Disc Mechanics and Biology

(2008) Casey L. Korecki et al.   SPINE