Article
Radiology, Nuclear Medicine & Medical Imaging
F. C. R. Staal, M. Taghavi, D. J. van der Reijd, F. M. Gomez, F. Imani, E. G. Klompenhouwer, D. Meek, S. Roberti, M. de Boer, D. M. J. Lambregts, R. G. H. Beets-Tan, M. Maas
Summary: The study aimed to investigate whether CT-based radiomics of the ablation zone (AZ) can predict local tumour progression (LTP) after thermal ablation for colorectal liver metastases (CRLM). Results showed that combining clinical features and radiomics features in a combined model yielded a better prediction of LTP compared to using radiomics alone. CT-based radiomics of the AZ and periablational rim (PAR) may have the potential to aid in predicting LTP during follow-up in patients with CRLM.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Tae-Hyung Kim, Jeong Min Lee, Dong Ho Lee, Ijin Joo, Sae-Jin Park, Jung Hee Yoon
Summary: This study compared the local tumor progression (LTP) of percutaneous no-touch radiofrequency ablation (NtRFA) with conventional radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) <= 5 cm through a systematic review and meta-analysis. The results showed that NtRFA had a lower LTP rate of 6% compared to conventional RFA.
EUROPEAN RADIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Won-Gun Yun, Youngmin Han, Mirang Lee, Young Jae Cho, Hye-Sol Jung, Wooil Kwon, Jin-Young Jang
Summary: Patients with PDAC and stable recurrent liver lesions should be considered for local treatment, as it can significantly improve survival.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Roberto L. Cazzato, Pierre De Marini, Ian Leonard-Lorant, Danoob Dalili, Guillaume Koch, Pierre A. Autrusseau, Theo Mayer, Julia Weiss, Pierre Auloge, Julien Garnon, Afshin Gangi
Summary: This retrospective study reported on the safety, pain relief, and local tumor control achieved with percutaneous ablation of sacral bone metastases. The results showed significant long-lasting pain relief with this treatment, although local tumor control appeared sub-optimal and further investigations are needed to confirm these findings.
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Peter Schullian, Edward Johnston, Gregor Laimer, Daniel Putzer, Gernot Eberle, Arno Amann, Maria Effenberger, Manuel Maglione, Martin C. Freund, Alexander Loizides, Reto Bale
Summary: The study assessed the frequency of major complications after multi-probe stereotactic radiofrequency ablation (SRFA) in a large cohort of patients over 15 years and identified risk factors for adverse events. The 30-day mortality after SRFA was 0.5% with an overall major complication rate of 7.4%. History of bile duct surgery/intervention, number of coaxial needles, and tumor location in certain segments were independent prognostic factors for major complications. Experience and adaptations over time contributed to a significant decrease in complications.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maria J. Valkema, Berend J. van der Wilk, Ben M. Eyck, Bas P. L. Wijnhoven, Manon C. W. Spaander, Michail Doukas, Sjoerd M. Lagarde, Wendy M. J. Schreurs, Mark J. Roef, J. Jan B. van Lanschot, Roelf Valkema
Summary: Active surveillance for patients with esophageal cancer and a clinically complete response (cCR) after neoadjuvant chemoradiotherapy (nCRT) involves accurate clinical response evaluations. F-18-FDG PET/CT scans can be useful for detecting tumor recurrence during active surveillance. In patients with ongoing cCR, the lowest SULmax was reached at 11 months after nCRT, suggesting resolution of radiation-induced esophagitis.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Review
Surgery
Seong Wook Shin, Keun Soo Ahn, Sang Woo Kim, Tae-Seok Kim, Yong Hoon Kim, Koo Jeong Kang
Summary: This study found that liver resection (LR) is more effective than local ablation therapies (such as RFA, MWA, and RFA plus TACE) in treating HCC within the Milan criteria. Specifically, LR has better 5-year recurrence-free survival and lower local recurrence rates compared to local ablation therapies.
Article
Surgery
Seong Eun Ko, Min Woo Lee, Ji Hye Min, Soo Hyun Ahn, Hyunchul Rhim, Tae Wook Kang, Kyoung Doo Song, Jong Man Kim, Gyu-Seong Choi, Dong Ik Cha, Hyo Keun Lim
Summary: This study evaluated the risk factors associated with technical failure after laparoscopic radiofrequency ablation for subcapsular hepatocellular carcinomas, identifying LTP lesion, invisibility of the index tumor on laparoscopy, and peri-hepatic vein location of the tumor as risk factors for technical failure. The cumulative LTP rates at 1, 3, and 5 years were estimated to be 2.8%, 4.8%, and 4.8%, respectively.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Haiyi Long, Xiaoyu Zhou, Xiaoer Zhang, Jieyi Ye, Tongyi Huang, Longfei Cong, Xiaoyan Xie, Guangliang Huang
Summary: The efficiency of three-dimensional (3D) and two-dimensional (2D) contrast-enhanced ultrasound (CEUS)-derived techniques in evaluating the ablative margin (AM) after radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) was compared. The study found that 3D CEUS fusion imaging (3D CEUS-FI) excelled in the evaluation of AM compared to 2D CEUS point-to-point imaging (2D CEUS-PI). 3D CEUS-FI had equivalent efficacy in predicting local tumor progression (LTP) and had the advantage of time-saving.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Andrew Ragheb, Aimen Vanood, Daniel K. Fahim
Summary: The study analyzed the effectiveness of RFA and kyphoplasty in treating breast cancer patients with metastatic spinal fractures. The results showed that the addition of RFA can reduce local tumor recurrence while providing similar pain relief benefits.
WORLD NEUROSURGERY
(2022)
Article
Oncology
Maria Villamonte, Fernando Burdio, Eva Pueyo, Ana Andaluz, Xavier Moll, Enrique Berjano, Aleksander Radosevic, Luis Grande, Miguel Pera, Benedetto Ielpo, Patricia Sanchez-Velazquez
Summary: The study aimed to compare the impact of an additional application of RF energy on the top of the resection surface on local recurrence in liver surgery. The results showed that additional margin coagulation (AMC) was associated with lower local recurrence, and the use of RF applicator was significantly related to reduced local recurrence. The Control group had smaller coagulation widths compared to the AMC group.
Article
Oncology
Yangmeihui Song, Fang Liu, Weiwei Ruan, Fan Hu, Muhsin H. Younis, Zairong Gao, Jie Ming, Tao Huang, Weibo Cai, Xiaoli Lan
Summary: PET/MR technology, combining MRI and PET capabilities, shows potential in achieving high diagnostic performance for refractory malignancies in DTC patients. Compared to PET/CT, PET/MR demonstrates better detection rates and sensitivity in assessing recurrent DTC lesions and lymph node metastases, providing more precise diagnostic information without additional ionizing radiation. Further studies and economic analysis are needed for scaling-up prospective applications.
Article
Radiology, Nuclear Medicine & Medical Imaging
Qian Cai, Yize Mao, Siqi Dai, Feng Gao, Qian Xiao, Wanming Hu, Tao Qin, Qiuxia Yang, Zhaozhou Li, Du Cai, Min-Er Zhong, Kefeng Ding, Xiao-Jian Wu, Rong Zhang
Summary: This multicenter study aimed to investigate the correlation between the growth pattern of liver metastases on preoperative MRI and early recurrence in patients with colorectal cancer liver metastases. The results showed that FEP and NC type liver metastases were associated with early recurrence, which could guide the clinical treatment of patients with this condition.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
Cheng-Maw Ho, Chih-Hsin Lee, Ming-Chia Lee, Jun-Fu Zhang, Chin-Hua Chen, Jann-Yuan Wang, Rey-Heng Hu, Po-Huang Lee
Summary: This study analyzed the survival of patients with post-transplant HCC recurrence, finding that early recurrence within two years after surgery had a poorer prognosis compared to late recurrence. Factors such as transplant era before 2008 and radiofrequency ablation were associated with better outcomes, while receiving sorafenib and radiotherapy were linked to poorer prognosis.
FRONTIERS IN ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Tae-Yon Sung, Dong Eun Song, Tae Yong Kim, Jeong Hyun Lee
Summary: Radiofrequency ablation (RFA) is effective and safe for local control of recurrent thyroid cancer in the central neck compartment after total thyroidectomy, even for tumors invading the airways. The complete disappearance rate is highest for recurrent tumors not in contact with the trachea. The overall complication rate is 21.4%.
EUROPEAN RADIOLOGY
(2021)
Review
Oncology
Madelon Dijkstra, Sanne Nieuwenhuizen, Robbert S. Puijk, Bart Geboers, Florentine E. F. Timmer, Evelien A. C. Schouten, Hester J. Scheffer, Jan J. J. de Vries, Johannes C. F. Ket, Kathelijn S. Versteeg, Martijn R. Meijerink, M. Petrousjka van den Tol
Summary: The potential additive value of neoadjuvant chemotherapy prior to repeat local treatment for recurrent colorectal liver metastases remains unclear, with conflicting results from limited studies. Recommendations for routine use of neoadjuvant chemotherapy are not supported by the inconclusive findings of this meta-analysis, highlighting the need for further investigation in future randomized controlled trials.
Letter
Cardiac & Cardiovascular Systems
M. Vermeulen, J. W. H. Kruimer, W. R. R. Farid, M. W. Dercksen, J. Buijsen, M. R. Meijerink, W. K. G. Leclercq
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2021)
Article
Oncology
Madelon Dijkstra, Sanne Nieuwenhuizen, Robbert S. Puijk, Florentine E. F. Timmer, Bart Geboers, Evelien A. C. Schouten, Jip Opperman, Hester J. Scheffer, Jan J. J. de Vries, Rutger-Jan Swijnenburg, Kathelijn S. Versteeg, Birgit I. Lissenberg-Witte, M. Petrousjka van den Tol, Martijn R. Meijerink
Summary: The study compared the safety, efficacy, and survival outcomes of repeat thermal ablation versus repeat partial hepatectomy in patients with recurrent colorectal liver metastases. Results showed that there were no significant differences in terms of overall survival, recurrence rates, and complications between the two treatment modalities, but patients who underwent repeat thermal ablation had a shorter length of hospital stay.
Review
Oncology
Florentine E. F. Timmer, Bart Geboers, Sanne Nieuwenhuizen, Madelon Dijkstra, Evelien A. C. Schouten, Robbert S. Puijk, Jan J. J. de Vries, M. Petrousjka van den Tol, Anna M. E. Bruynzeel, Mirte M. Streppel, Johanna W. Wilmink, Hans J. van Der Vliet, Martijn R. Meijerink, Hester J. Scheffer, Tanja D. de Gruijl
Summary: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a poor prognosis. While immunotherapy has revolutionized the treatment of other advanced cancers, its effectiveness in PDAC is limited due to the immunosuppressive and hard-to-reach tumor microenvironment. However, various immunotherapies have shown potential in initiating immune responses, suggesting an immune potentiating effect. Successful PDAC treatment may rely on the synergistic effects of combination immunotherapies.
Article
Oncology
Bart Geboers, Florentine E. F. Timmer, Alette H. Ruarus, Johanna E. E. Pouw, Evelien A. C. Schouten, Joyce Bakker, Robbert S. Puijk, Sanne Nieuwenhuizen, Madelon Dijkstra, M. Petrousjka van den Tol, Jan J. J. de Vries, Daniela E. Oprea-Lager, C. Menke-van der Houven van Oordt, Hans J. van der Vliet, Johanna W. Wilmink, Hester J. Scheffer, Tanja D. de Gruijl, Martijn R. Meijerink
Summary: IRE is a novel technique that induces cell death through high-voltage electrical pulses applied around the tumor, which may reduce immune suppression and promote expansion of tumor-specific T cells. Combining IRE with immunotherapeutic drugs has the potential to generate a durable antitumor response.
Article
Biochemistry & Molecular Biology
Madelon Dijkstra, Sanne Nieuwenhuizen, Robbert S. Puijk, Florentine E. F. Timmer, Bart Geboers, Evelien A. C. Schouten, Jip Opperman, Hester J. Scheffer, Jan J. J. de Vries, Kathelijn S. Versteeg, Birgit Lissenberg-Witte, M. Petrousjka van den Tol, Martijn R. Meijerink
Summary: This study evaluated the impact of primary tumor sidedness of CRC, RAS and BRAF mutations, and MSI status on complications, survival outcomes, and local tumor progression following surgery and thermal ablation in patients with CRLM. The findings suggest the importance of wider margins for reducing LTP rates in patients with RAS mutated CRLM, particularly for thermal ablation, and highlight the potential contribution of upfront knowledge of molecular biomarkers to improve oncological outcomes.
Article
Oncology
Madelon Dijkstra, Sanne Nieuwenhuizen, Robbert S. Puijk, Florentine E. F. Timmer, Bart Geboers, Evelien A. C. Schouten, Jip Opperman, Hester J. Scheffer, Jan J. J. de Vries, Kathelijn S. Versteeg, Birgit Lissenberg-Witte, Martijn R. Meijerink, Monique Petrousjka van den Tol
Summary: This study found that adding neoadjuvant chemotherapy before repeat local treatment for colorectal liver metastases did not improve survival rates, recurrence rates, or impact complications and hospital stay duration. The results do not support routine use of neoadjuvant chemotherapy before repeat local treatment.
Review
Oncology
Roberto Iezzi, Afshin Gangi, Alessandro Posa, Uei Pua, Ping Liang, Ernesto Santos, Anil N. Kurup, Alessandro Tanzilli, Lorenzo Tenore, Davide De Leoni, Dimitrios Filippiadis, Felice Giuliante, Vincenzo Valentini, Antonio Gasbarrini, Shraga N. Goldberg, Martijn Meijerink, Riccardo Manfredi, Alexis Kelekis, Cesare Colosimo, David C. Madoff
Summary: Interventional oncology (IO) employs minimally invasive procedures to provide lower-risk alternatives to traditional medical and surgical therapies for cancer patients. This article aims to review new indications for locoregional IO treatments and summarize the expert discussion and report from the MIOLive Meets SIO session during the last Mediterranean Interventional Oncology Live congress held in Rome, Italy.
Article
Radiology, Nuclear Medicine & Medical Imaging
Bart Geboers, Susan Van der Lei, Louiza T. E. Kloppenborg, Rianne M. Boon, Florentine E. F. Timmer, Robbert S. Puijk, Jan J. J. de Vries, Hester J. Scheffer, Martijn R. Meijerink
Summary: Visibility is crucial for optimal treatment planning and control during ablative procedures. Transcatheter CT arteriography has proven to be of additional value for thermal liver ablation, with potential application in other indications and ablation techniques. This essay presents cases illustrating the use of transcatheter CT arteriography for guidance during the treatment of pancreatic cancer, highlighting its ability to improve visibility of vascular structures and monitor intraprocedural complications in real-time.
JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Martijn R. Meijerink, Reto Bale, Ajith K. Siriwardena
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Oncology
Madelon Dijkstra, Susan van der Lei, Robbert S. Puijk, Hannah H. Schulz, Danielle J. W. Vos, Florentine E. F. Timmer, Hester J. Scheffer, Tineke E. Buffart, M. Petrousjka van den Tol, Birgit I. Lissenberg-Witte, Rutger-Jan Swijnenburg, Kathelijn S. Versteeg, Martijn R. Meijerink
Summary: Thermal ablation is safe and effective for the treatment of small-size unresectable colorectal liver metastases (CRLM). This comparative study analyzed the outcomes of intermediate-size versus small-size CRLM and found no significant difference in overall survival between the two groups. However, the small-size group had better local control. The study also showed that thermal ablation improved the long-term local control of intermediate-size CRLM over time.
Article
Radiology, Nuclear Medicine & Medical Imaging
Lemonitsa H. Mammatas, Maqsood Yaqub, N. Harry Hendrikse, Otto S. Hoekstra, Richard J. Honeywell, Robert C. Schuit, Martijn Meijerink, Lothar A. Schwarte, Godefridus J. Peters, Henk M. W. Verheul, Adriaan A. Lammertsma, C. Willemien Menke-van der Houven van Oordt
Summary: Sorafenib has shown clinical benefit in some patients, but its potential toxicity affects all patients. This study aimed to evaluate the predictive value of C-11-sorafenib and O-15-H2O PET in treatment efficacy. However, while C-11-sorafenib PET did not predict intratumoral sorafenib concentrations, a decrease in tumor perfusion after therapy showed an association with clinical benefit, suggesting further investigation is needed.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Oncology
Sanne Nieuwenhuizen, Madelon Dijkstra, Robbert S. Puijk, Florentine E. F. Timmer, Irene M. Nota, Jip Opperman, Bente van den Bemd, Bart Geboers, Alette H. Ruarus, Evelien A. C. Schouten, Jan J. J. de Vries, Hester J. Scheffer, Anne M. van Geel, Jan Hein T. M. van Waesberghe, Rutger-Jan Swijnenburg, Kathelijn S. Versteeg, Birgit Lissenberg-Witte, M. Petrousjka van den Tol, Cornelis J. A. Haasbeek, Martijn R. Meijerink
Summary: Vaginal epithelial shedding is a common gynecological issue that may result from the loss of vaginal epithelial cells. Treatment can involve medication or surgery, depending on the severity of the condition.
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
