Review
Radiology, Nuclear Medicine & Medical Imaging
Masaaki Hori, Akifumi Hagiwara, Masami Goto, Akihiko Wada, Shigeki Aoki
Summary: Low-field magnetic resonance imaging systems have experienced a revival due to advancements in technology. Compared to high-field systems, they offer unique advantages in clinical applications.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Medicine, General & Internal
Monika Ostrowska, Emil Michalski, Piotr Gietka, Malgorzata Manczak, Magdalena Posadzy, Iwona Sudol-Szopinska
Summary: This study compared MRI findings between patients clinically suspected of Juvenile Idiopathic Arthritis (JIA) and patients with ankle arthralgia of unknown cause. The results showed that inflammatory features were observed on MRI, with tenosynovitis being significantly more common in JIA patients. However, the MRI summarized score did not effectively differentiate between JIA and non-JIA patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Veterinary Sciences
Carla Ulrike Doll, Kerstin von Pueckler, Julia Offhaus, Dagmar Berner, Janina Burk
Summary: This study investigated the application of MRI in chronic tendon lesions in equine medicine, and compared the impact of different sequences and tendon positioning on lesion detection. The results showed that the T1w FLASH sequence with vertical tendon positioning in high-field MRI was the most effective for diagnosing tendon lesions, while the T1w SE sequence with horizontal tendon positioning had poor performance.
VETERINARY SCIENCES
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Rafael Heiss, Armin M. Nagel, Frederik B. Lain, Michael Uder, Sebastian Bickelhaupt
Summary: Magnetic resonance imaging (MRI) plays a crucial role in diagnostic imaging, with scanners of 1.5 to 3 T field strengths being most commonly used. The introduction of high-performance low-field MRI systems may enhance clinical utilization and availability while reducing costs.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Rheumatology
Torsten Diekhoff, Iris Eshed, Felix Radny, Katharina Ziegeler, Fabian Proft, Juliane Greese, Dominik Deppe, Robert Biesen, Kay Geert Hermann, Denis Poddubnyy
Summary: The study found that compared to CT and MRI, X-ray had lower sensitivity and inferior specificity for axSpA. However, CT showed the best inter-rater reliability, highlighting the importance of structural lesions for the differential diagnosis in axSpA.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hanns-Christian Breit, Jan Vosshenrich, Verena Hofmann, Thilo Rusche, Balazs K. Kovacs, Michael Bach, Sebastian Manneck, Dorothee Harder
Summary: This study assessed the potential of a 0.55T low-field MRI system in lumbar spine imaging and found that the image quality at 0.55T was lower compared to 1.5T. However, the use of advanced postprocessing techniques improved the imaging quality and the interrater agreement was good.
ACADEMIC RADIOLOGY
(2023)
Article
Rheumatology
Marie Wetterslev, Mikkel Ostergaard, Inge J. Sorensen, Ulrich Weber, Anne G. Loft, Gina Kollerup, Lars Juul, Gorm Thamsborg, Ole R. Madsen, Jakob M. Moller, Susanne J. Pedersen
Summary: This study aimed to combine the SPARCC SIJ structural score into three versions of a novel axSpA MRI SIJ Composite Structural Damage Score (CSDS) and test these in patients with axSpA. The results showed that CSDS stepwise and CSDS hierarchical demonstrated good construct validity and responsiveness, supporting further validation in larger clinical trials. The potential clinical implication is the assessment of SIJ damage progression by a composite score.
JOURNAL OF RHEUMATOLOGY
(2021)
Article
Health Care Sciences & Services
Nienke J. Kleinrensink, Wouter Foppen, Iris ten Katen, Emmerik F. A. Leijten, Pim A. de Jong, Julia Spierings
Summary: This study evaluated the application of HEMRIS in patients with SpA and psoriasis, showing that some patients had changes in HEMRIS in a one-year interval, but these changes were not associated with changes in clinical disease activity.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Rheumatology
Sevtap Tugce Ulas, Felix Radny, Katharina Ziegeler, Iris Eshed, Juliane Greese, Dominik Deppe, Carsten Stelbrink, Robert Biesen, Hildrun Haibel, Valeria Rios Rodriguez, Judith Rademacher, Mikhail Protopopov, Fabian Proft, Denis Poddubnyy, Torsten Diekhoff
Summary: This study aimed to investigate whether self-reported diagnostic confidence can predict diagnostic accuracy in axial spondyloarthritis imaging. The results showed significant differences in diagnostic confidence between correct and incorrect responses for all imaging modalities, and self-reported diagnostic confidence can serve as useful information to predict diagnostic reliability.
Review
Physiology
Clement Prati, Thierry Lequerre, Benoit Le Goff, Bernard Cortet, Hechmi Toumi, Anne Tournadre, Hubert Marotte, Eric Lespessailles
Summary: A detailed anatomical description of the sacroiliac joint is crucial for understanding spondyloarthropathy, as sacroiliitis is its earliest and most common sign. Additionally, understanding the histopathology and immunological mechanisms of sacroiliac entheses is essential for comprehending the disease causation. This review focuses on the anatomical, histological, and immunohistological observations related to the development of sacroiliitis and discusses the sequencing of enthesitis, synovitis, and subchondral bone changes in spondyloarthropathy.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Merel de Leeuw den Bouter, Martin van Gijzen, Rob Remis
Summary: This paper introduces a MRI technique based on multiplicative regularization, which effectively suppresses noise and produces accurate reconstructions.
MAGNETIC RESONANCE IMAGING
(2021)
Article
Rheumatology
Alexis Ogdie, Taylor Blachley, Paul R. Lakin, Blessing Dube, Robert R. McLean, Peter Hur, Philip J. Mease
Summary: The study aimed to evaluate the presence of axial symptoms in patients with psoriatic arthritis (PsA) and examine the differences between patients with or without a diagnosis of axial PsA. It found that patients who reported elevated spine symptoms, regardless of whether they had a diagnosed axial PsA or not, had a worse quality of life and higher disease activity, indicating an unmet need in this patient population.
JOURNAL OF RHEUMATOLOGY
(2022)
Article
Rheumatology
Dominik Deppe, Kay-Geert Hermann, Fabian Proft, Denis Poddubnyy, Felix Radny, Mikhail Protopopov, Marcus R. Makowski, Torsten Diekhoff
Summary: In patients with axSpA, SWI depicts erosions and sclerosis more accurately than T1 spin echo MRI at 1.5T.
Article
Rheumatology
Victoria Furer, David Levartovsky, Jonathan Wollman, Irena Wigler, Daphna Paran, Ilana Kaufman, Ofir Elalouf, Sara Borok, Marina Anouk, Hagit Sarbagil-Maman, Mark Berman, Ari Polachek, Hagit Matz, Gideon Flusser, Ido Druckmann, Iris Eshed, Ori Elkayam
Summary: The study found that the prevalence of active sacroiliitis in a real-life sample of patients with PsA was 26%, with a lower prevalence of nonradiographic sacroiliitis (11%) compared to radiographic sacroiliitis (28.7%) in patients with longer disease duration. Inflammatory back pain was not a sensitive indicator for early-stage sacroiliitis.
JOURNAL OF RHEUMATOLOGY
(2021)
Article
Medicine, General & Internal
Milica Jeremic Knezevic, Aleksandar Knezevic, Jasmina Boban, Aleksandra Maletin, Bojana Milekic, Daniela Djurovic Koprivica, Tatjana Puskar, Robert Semnic
Summary: This study aimed to investigate the agreement between clinical diagnosis based on RDC/TMD and high-field MRI findings of TMJs in asymptomatic females. The findings showed low agreement between clinical examination and MRI results in anterior dislocation with reduction, as well as in osteoarthritic changes. However, RDC/TMD had a low rate of false positive diagnoses in asymptomatic patients and remains a sensible method for clinical diagnosis and avoiding overtreatment.
Article
Rheumatology
Katharina Ziegeler, Sevtap Tugce Ulas, Denis Poddubnyy, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Kay Geert A. Hermann, Torsten Diekhoff
Summary: Joint shape variations are associated with inflammatory lesions on SI joint MRIs in axSpA patients. This should be taken into consideration in future research on the interplay of mechanical strain and inflammation in axSpA.
Meeting Abstract
Rheumatology
T. Diekhoff, D. Deppe, D. Poddubnyy, K. Ziegeler, F. Proft, K. G. Hermann, M. Protopopov, F. Radny, M. Makowski
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Meeting Abstract
Rheumatology
V. Rios Rodriguez, M. Torgutalp, H. Haibel, K. G. A. Hermann, F. Proft, M. Protopopov, J. Rademacher, J. Sieper, D. Poddubnyy
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Review
Rheumatology
Iris Eshed, Torsten Diekhoff, Kay Geert A. Hermann
Summary: Pelvic radiography is recommended as the initial imaging modality for suspected axSpA, but CT and MRI are superior for diagnosing sacroiliitis. Recent findings suggest that low-dose CT of the sacroiliac joints and MRI with sequences sensitive to cortical bone are more accurate and reliable than radiographs.
CURRENT OPINION IN RHEUMATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Ulrike Haug, Bianca Kollhorst, Tania Schink, Kathrin Thoene, Katarina Dathe, Christof Schaefer, Marlies Onken
Summary: This study used the German Pharmacoepidemiological Research Database (GePaRD) to demonstrate a strong association between VPA exposure in early pregnancy and the occurrence of spina bifida.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2023)
Article
Pharmacology & Pharmacy
Annemarie Voss, Elisabeth Smits, Karin M. A. Swart, Yanina Balabanova, Gunnar Brobert, Kiliana Suzart-Woischnik, Ron M. C. Herings, Tania Schink, Ulrike Haug
Summary: Since its market approval in 2011, the use of rivaroxaban, a direct oral anticoagulant, has significantly increased in Europe. The baseline characteristics of new rivaroxaban users with non-valvular atrial fibrillation in Germany and the Netherlands have changed over time, with an increasing proportion of patients in Germany not using oral anticoagulants prior to starting rivaroxaban and an increasing proportion of patients in the Netherlands having heart failure at baseline.
DRUGS-REAL WORLD OUTCOMES
(2023)
Letter
Obstetrics & Gynecology
T. Schink, M. Braitmaier, U. Haug
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Katharina Platzbecker, Helge Mueller-Fielitz, Ronja Foraita, Matthias J. Koepp, Annemarie Voss, Rene Pflock, Roland Linder, Iris Pigeot, Tania Schink, Markus Schwaninger
Summary: This study aimed to investigate whether treatment of atrial fibrillation (AF) with direct oral anticoagulants (DOACs) affects the risk of epilepsy compared to treatment with the vitamin K antagonist phenprocoumon (PPC). The results showed that patients with AF treated with DOACs had a higher risk of epilepsy compared to PPC treatment.
Article
Pharmacology & Pharmacy
Luis Alberto Garcia Rodriguez, Ana Ruigomez, Tania Schink, Annemarie Voss, Elisabeth Smits, Karin M. A. Swart, Yanina Balabanova, Kiliana Suzart-Woischnik, Gunnar Brobert, Ron M. C. Herings
Summary: This study evaluated the safety and effectiveness of rivaroxaban versus vitamin K antagonists in stroke prevention for patients with nonvalvular atrial fibrillation in Europe. The results showed that the incidence of intracranial bleeding was generally lower with rivaroxaban, while gastrointestinal and urogenital bleeding were higher.
EXPERT OPINION ON DRUG SAFETY
(2023)
Correction
Radiology, Nuclear Medicine & Medical Imaging
Keno K. Bressem, Lisa C. Adams, Fabian Proft, Kay Geert A. Hermann, Torsten Diekhoff, Laura Spiller, Stefan M. Niehues, Marcus R. Makowski, Bernd Hamm, Mikhail Protopopov, Valeria Rios Rodriguez, Hildurn Haibel, Judith Rademacher, Murat Torgutalp, Robert G. Lambert, Xenofon Baraliakos, Walter P. Maksymowych, Janis L. Vahldiek, Denis Poddubny
Article
Rheumatology
Torsten Diekhoff, Denis Poddubnyy, Fabian Proft, Katharina Ziegeler, Dominik Deppe, Christoph Niedermeier, Kay Geert A. Hermann
Summary: By comparing CT and MRI scans of patients with axial SpA, it was found that joint space lesions show increased density and may contain calcified matrix, suggesting new bone formation. The proportion of calcified matrix gradually increases in type C lesions.
Article
Medicine, General & Internal
Dominik Deppe, Katharina Ziegeler, Kay Geert A. Hermann, Fabian Proft, Denis Poddubnyy, Felix Radny, Marcus R. R. Makowski, Maximilian Muhle, Torsten Diekhoff
Summary: This study aimed to evaluate the ability of low-dose dual-energy computed tomography (ld-DECT) virtual non-calcium (VNCa) images to detect bone marrow pathologies in patients with axial spondyloarthritis (axSpA). Sixty-eight patients underwent both ld-DECT and MRI for assessment. The accuracy of ld-DECT in detecting osteitis and fatty bone marrow deposition was evaluated, and correlations with MRI were calculated. The results showed that ld-DECT had limited sensitivity and specificity in detecting these pathologies, and higher radiation might be needed for more accurate analysis.
Meeting Abstract
Rheumatology
Robert G. Lambert, Xenofon Baraliakos, Stephanie Bernard, John Carrino, Torsten Diekhoff, Iris Eshed, Kay-Geert Hermann, Nele Herregods, Jacob Jaremko, Lennart Jans, Anne Jurik, John O'Neill, Monique Reijnierse, Michael Tuite, Walter P. Maksymowych
ARTHRITIS & RHEUMATOLOGY
(2022)
Meeting Abstract
Rheumatology
Torsten Diekhoff, Iris Eshed, Chiara Giraudo, Hildrun Haibel, Kay-Geert Hermann, Manouk de Hooge, Lennart Jans, Anne Jurik, Robert G. Lambert, Pedro Machado, Walter P. Maksymowych, Michael Mallinson, Helena Marzo-Ortega, Victoria Navarro-Compan, Susanne Pedersen, Mikkel Ostergaard, Monique Reijnierse, Martin Rudwaleit, Fernando Andres Sommerfleck, Ulrich Weber, Xenofon Baraliakos, Denis Poddubnyy
ARTHRITIS & RHEUMATOLOGY
(2022)
Meeting Abstract
Rheumatology
Sandra Hermann, Andriko Palmowski, Bukrhard Muche, Kay-Geert Hermann, Edgar Wiebe, Frank Buttgereit
ARTHRITIS & RHEUMATOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
