Article
Multidisciplinary Sciences
Hongchang Wang, Kawal Sawhney
Summary: Researchers have successfully generated omnidirectional differential phase images using X-ray differential phase contrast imaging, providing more information for studying complex samples and enabling simultaneous extraction of omnidirectional dark-field images to study ordered scattering structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Hongchang Wang, Kawal Sawhney
Summary: This article introduces a method for generating omnidirectional differential phase images by scanning a randomly structured modulator, which provides more information than traditional imaging methods and allows the simultaneous extraction of omnidirectional dark-field images for studying strongly ordered scattering structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Metallurgy & Metallurgical Engineering
Youhong Peng, Kesong Miao, Wei Sun, Chenglu Liu, Hao Wu, Lin Geng, Guohua Fan
Summary: Characterizing the microstructure and deformation mechanism of metallic materials is crucial for understanding the microstructure-property relationship. Advanced synchrotron radiation facilities have enabled non-destructive visualization of full-field structural information in three dimensions, contributing to significant progress in recent decades. Future innovations in next-generation synchrotron radiation and emerging technologies hold great potential for further advancements in material characterization.
ACTA METALLURGICA SINICA-ENGLISH LETTERS
(2022)
Article
Polymer Science
Collin W. Foster, Sreevishnu Oruganti, Francesco Panerai
Summary: This study quantitatively analyzed the microstructural evolution and porous network development of Room Temperature Vulcanized (RTV) silicone pyrolysis at high temperatures using in situ high-temperature X-ray computed micro-tomography. The results showed that the microstructure evolution and porous network development were dependent on the heating rate, and the bulk sample volume change, porosity, pore network size, and densification were evaluated using X-ray attenuation. The findings of this study are important for the development of multi-physics models for thermal response.
POLYMER DEGRADATION AND STABILITY
(2023)
Review
Chemistry, Multidisciplinary
Loic Bertrand, Mathieu Thoury, Pierre Gueriau, Etienne Anheim, Serge Cohen
Summary: The chemical study of materials from natural history and cultural heritage presents challenges due to their complexity and non-reproducibility, but also offers innovative approaches for historical information. Synchrotron methods have been crucial in studying heritage objects, providing speciation information and high-resolution imaging. These developments have paved the way for novel approaches in characterizing ancient and historical materials, with implications for machine learning methods and related fields beyond heritage studies.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Article
Cell Biology
Ying Zhu, Dragana Ponjevic, John R. Matyas, Steven K. Boyd
Summary: This study evaluated articular cartilage structure ex vivo using contrast-enhanced X-ray microscopy and phosphotungstic acid staining, showing 16 hours as the optimal staining time. The technique offers advantages over routine histopathology by preserving intact articular cartilage and subchondral bone in 3D imaging and analyzing diagnostic features of cartilage.
CONNECTIVE TISSUE RESEARCH
(2021)
Article
Medicine, General & Internal
Eunjue Yi, Naoki Sunaguchi, Jeong Hyeon Lee, Chul-Yong Kim, Sungho Lee, Sanghoon Jheon, Masami Ando, Yangki Seok
Summary: The study evaluated the clinical implication of synchrotron radiation imaging techniques for human lung adenocarcinoma in comparison with pathologic examination. The research found that synchrotron radiation could provide high-resolution images of lung adenocarcinoma which were highly correlated with images from pathologic examinations.
Article
Orthopedics
Shannon K. Walsh, Rikin Soni, Lisa M. Arendt, Melissa C. Skala, Corinne R. Henak
Summary: The study revealed age-dependent metabolic activity in cartilage, with metabolic dysfunction impacting gene expression related to tissue maintenance. Glycolysis, oxidative phosphorylation activity, and optical redox ratio were positively correlated with severity of cartilage damage.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Medicine, General & Internal
Simone Fantoni, Ilenia Gabucci, Paolo Cardarelli, Gianfranco Paterno, Angelo Taibi, Virginia Cristofori, Claudio Trapella, Armando Bazzani, Marta Assenza, Alice Zanna Bonacorsi, Daniele Conti, Fabio Baruffaldi
Summary: This study assessed a new cationic contrast agent, CA4+, in the spatial distribution and saturation time in bovine cartilage. The results showed that CA4+ was distributed in three distinct layers in the cartilage and had a longer saturation time. Clinical CT results confirmed the contrast enhancement effect of CA4+ in the cartilage, with different regions showing different degrees of contrast enhancement. In addition, partial washout of the cartilage was observed.
Review
Chemistry, Multidisciplinary
Akio Yoneyama, Daiko Takamatsu, Thet-Thet Lwin, Shigehito Yamada, Tetsuya Takakuwa, Kazuyuki Hyodo, Keiichi Hirano, Satoshi Takeya
Summary: Crystal-based X-ray interferometry (CXI) detects X-ray phase shifts with the highest sensitivity among the X-ray phase-detecting methods. Phase-contrast X-ray imaging (PCXI) using CXI has the highest density resolution and has been widely applied in various fields. Novel imaging methods have also been developed to take advantage of CXI's high sensitivity, such as visualization of the effective atomic number and the three-dimensional temperature. This article reviews the principles, history, and potential applications of PCXI and CXI systems.
APPLIED SCIENCES-BASEL
(2023)
Article
Nanoscience & Nanotechnology
C. Yildirim, C. Jessop, J. Ahlstrom, C. Detlefs, Y. Zhang
Summary: Assessing local residual stress and orientation within steel grains at nanometer resolution remains challenging. Using dark field X-ray microscopy, 3D lattice variations in pearlitic steel were mapped, showing orientation variations and compressive elastic strain. These variations impact manufacturing processes and mechanical properties, but there is no direct correlation between measured compressive strain and lattice orientation.
SCRIPTA MATERIALIA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Manuela Frank, Theresa Urban, Konstantin Willer, Wolfgang Noichl, Fabio De Marco, Rafael Schick, Bernhard Gleich, Alexander Schegerer, Ursula Lechel, Pascal Meyer, Juergen Mohr, Thomas Koehler, Andre Yaroshenko, Ingo Maack, Thomas Pralow, Roland Proksa, Bernhard Renger, Peter Noel, Alexander Fingerle, Daniela Pfeiffer, Ernst Rummeny, Julia Herzen, Franz Pfeiffer
Summary: The study evaluated the dose characteristics for patient examinations at the first clinical X-ray dark-field chest radiography system and found that the effective patient dose is within a clinically acceptable range. The results showed that the effective dose for examined patients is similar to standard dose values for chest radiography.
Article
Cell Biology
Annie Horng, Johannes Stroebel, Tobias Geith, Stefan Milz, Alexandra Pacureanu, Yang Yang, Peter Cloetens, Goran Lovric, Alberto Mittone, Alberto Bravin, Paola Coan
Summary: This study investigated the feasibility of using X-ray phase-contrast imaging (X-PCI) for high-resolution analysis of tissue degeneration in human cartilage samples. The results showed that X-PCI provided a three-dimensional visualization of cartilage samples down to a cellular level, with good correlation to histologic and transmission electron microscopy images. X-PCI has the potential to serve as a tissue-preserving, staining-free and volumetric virtual histology tool for examining cartilage behavior in laboratory experiments.
JOURNAL OF BIOMEDICAL SCIENCE
(2021)
Article
Engineering, Biomedical
Sheetal R. Inamdar, Sylvain Prevost, Nicholas J. Terrill, Martin M. Knight, Himadri S. Gupta
Summary: In this study, synchrotron small-angle X-ray scattering (SAXS) combined with in-situ cyclic loading of bovine articular cartilage explants was utilized to measure the fibrillar response in deep zone articular cartilage. The findings showed that under repeated cyclic loading, the collagen fibrils can reversibly change the width of the fibrillar orientation distribution while maintaining a consistent average direction of orientation. The study also demonstrated that inflammation can disrupt collagen rearrangement under cyclic loading and lead to reduced tissue stiffness.
ACTA BIOMATERIALIA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Uttam Pyakurel, Weiyuan Sun, Pikting Cheung, Desiree D'Moore, Xiaoyun Zhang, Carolyn A. MacDonald, Jonathan C. Petruccelli
Summary: This study developed a practical X-ray phase and dark-field imaging system using structured illumination with a wire mesh and polycapillary optics for coherence enhancement. Mesh-shifting algorithm and deblurring technique improved resolution and accuracy in phase and DF imaging. The system demonstrated significant potential for diagnostic imaging in a clinical setting.
Article
Radiology, Nuclear Medicine & Medical Imaging
Hila Tal Tamir, Dana Stav, Yitzhac Hadad, Rivka Kessner
Summary: This study aimed to characterize thyroid nodules seen on Spectral Detector computed tomography (SDCT) and compare them with their Thyroid Imaging Reporting and Data System (TI-RADS) category on Ultrasound (US). The results showed that the spectral results of SDCT can assist in differentiating thyroid nodules of different risk levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Volha Nizhnikava, Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kraeuter, Horst Olschewski, Michael Fuchsjaeger, Gert Reiter
Summary: The purpose of this study was to investigate the associations between cardiac magnetic resonance feature-tracking-derived myocardial strain parameters and volumetric function and hemodynamic parameters in patients with pulmonary hypertension. The results showed that impairment of myocardial strains was more strongly associated with alterations in ventricular function parameters than elevated pulmonary arterial pressure, limiting the diagnostic information of myocardial strain parameters in pulmonary hypertension.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ling Qian, Rui-lin Quan, Xiao-xi Chen, Yang-yi Lin, Xiao-li Jing, Qing Gu, Chang-ming Xiong, Jian-guo He, Ai-hua Zhi
Summary: The purpose of this study was to investigate the imaging characteristics and prognostic factors for the long-term survival of Behcet's disease (BD) with arterial involvement. The results showed that arterial lesions associated with BD usually involve multiple arteries and manifest differently in different types of arteries. Cardiac involvement and pulmonary artery aneurysm/dilation were independent prognostic factors for the survival of BD patients with arterial involvement.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Yong Xie, Jian Wang, Yinghua Zou
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daria Kifjak, Maximilian Hochmair, Daniel Sobotka, Alexander R. Haug, Raphael Ambros, Florian Prayer, Benedikt H. Heidinger, Sebastian Roehrich, Ruxandra-Iulia Milos, Wolfgang Wadsak, Thorsten Fuereder, Dagmar Krenbek, Andreas Fazekas, Michael Meilinger, Marius E. Mayerhoefer, Georg Langs, Christian Herold, Helmut Prosch, Lucian Beer
Summary: The ability of pretreatment PET parameters and peripheral blood biomarkers to predict PFS and OS in NSCLC patients treated with ICIT was assessed. The study found that MTV and the number of SOI were independent risk factors for progression and overall survival, and the combination of these factors improved risk stratification.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Jan-Lucca Hennes, Pauline Pannenbecker, Philipp Gruschwitz, Saif Afat, Judith Herrmann, Thorsten Alexander Bley, Andreas Steven Kunz
Summary: This study investigated the potential of tin prefiltration and virtual monoenergetic imaging (VMI) in suppressing metal artifacts in high-resolution CT images of the lower extremities. The results showed that VMI reconstructions had better artifact reduction compared to T3D. VMI110keV had the least image noise. In terms of image quality, interpretability of bone-metal interface, and overall image quality, VMI110keV performed the best.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yue Li, Huan Zhang, Lei Yue, Caixia Fu, Robert Grimm, Wenhua Li, Weijian Guo, Tong Tong
Summary: This study evaluated and compared the diagnostic value of diffusion-related texture analysis parameters from different magnetic resonance diffusion models in predicting the clinical response to chemotherapy in patients with colorectal liver metastases. Among the models, DKI-derived parameters showed the best performance for early prediction, followed by IVIM-derived parameters and DWI baseline features.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lu Wang, ShiXiong Zhang, Jun Xin
Summary: This study aimed to determine if sex differences in abdominal visceral fat composition and metabolism can help predict the prognosis of DLBCL patients. The results showed that females with certain fat composition and metabolism characteristics had worse progression-free survival, while no significant differences were found in males with DLBCL.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yu-ping Wu, Lan Wu, Jing Ou, Jin-ming Cao, Mao-yong Fu, Tian-wu Chen, Erika Ouchi, Jiani Hu
Summary: This study aimed to develop CT radiomics models to preoperatively identify lymph node (LN) status in resectable esophageal squamous cell carcinoma (ESCC) patients. The results showed that the combined model, integrating ESCC and LN radiomics features with clinical features, had the highest predictive ability among the three models. The combined model's predictive ability was validated in both the test and external validation cohorts.
EUROPEAN JOURNAL OF RADIOLOGY
(2024)