Synthesis of Oxindoles through Silver-Catalyzed Trifluoromethylation-, Difluoromethylation- and Arylsulfonylation-Cyclization Reaction ofN-Arylacrylamides

Direct Trifluoromethylation of the CH Bond

(2013) Hui Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Silver-Catalyzed Decarboxylative Acylarylation of Acrylamides with α-Oxocarboxylic Acids in Aqueous Media

(2013) Hua Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-Free Radical Azidoarylation of Alkenes: Rapid Access to Oxindoles by Cascade CN and CC Bond-Forming Reactions

(2013) Kiran Matcha et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Oxindoles by Iron-Catalyzed Oxidative 1,2-Alkylarylation of Activated Alkenes with an Aryl C(sp2)H Bond and a C(sp3)H Bond Adjacent to a Heteroatom

(2013) Wen-Ting Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Annulations toward Phosphorylated Oxindoles: Silver-Catalyzed Carbon-Phosphorus Functionalization of Alkenes

(2013) Ya-Min Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethylation Reactions for the Synthesis of β-Trifluoromethylamines

(2013) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed synthesis of trifluoromethyl-substituted isoxazolines

(2013) Yu-Tao He et al.   CHEMICAL COMMUNICATIONS

CuCl-catalyzed ortho trifluoromethylation of arenes and heteroarenes with a pivalamido directing group

(2013) Shangjun Cai et al.   CHEMICAL COMMUNICATIONS

Oxidative 1,2-difunctionalization of activated alkenes with benzylic C(sp3)–H bonds and aryl C(sp2)–H bonds

(2013) Ming-Bo Zhou et al.   CHEMICAL COMMUNICATIONS

Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C–H functionalization of alcohols

(2013) Yuan Meng et al.   CHEMICAL COMMUNICATIONS

A room temperature decarboxylation/C–H functionalization cascade by visible-light photoredox catalysis

(2013) Jin Xie et al.   CHEMICAL COMMUNICATIONS

Palladium-catalyzed desulfitative hydroarylation of alkynes with sodium sulfinates

(2013) Saiwen Liu et al.   CHEMICAL COMMUNICATIONS

Copper-Catalyzed Oxidative Benzylarylation of Acrylamides by Benzylic CH Bond Functionalization for the Synthesis of Oxindoles

(2013) Shi-Liu Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Concise synthesis of oxindole derivatives bearing a 3-trifluoroethyl group: Copper-catalyzed trifluoromethylation of acryloanilides

(2013) Hiromichi Egami et al.   JOURNAL OF FLUORINE CHEMISTRY

ortho-Perfluoroalkylation and Ethoxycarbonyldifluoromethylation of Aromatic Triazenes

(2013) Andreas Hafner et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Sulfonated Oxindoles by Potassium Iodide Catalyzed Arylsulfonylation of Activated Alkenes with Sulfonylhydrazides in Water

(2013) Xiaoqing Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Promoted Sandmeyer Trifluoromethylation Reaction

(2013) Jian-Jun Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethylation of Aryldiazonium Salts: Conversion of Amino Group into Trifluoromethyl Group

(2013) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Carboazidation of Arylacrylamides

(2013) Xiao-Hong Wei et al.   ORGANIC LETTERS

Silver-Catalyzed Radical Tandem Cyclization for the Synthesis of 3,4-Disubstituted Dihydroquinolin-2(1H)-ones

(2013) Wen-Peng Mai et al.   ORGANIC LETTERS

Copper- and Iron-Catalyzed Decarboxylative Tri- and Difluoromethylation of α,β-Unsaturated Carboxylic Acids with CF3SO2Na and (CF2HSO2)2Zn via a Radical Process

(2013) Zejiang Li et al.   ORGANIC LETTERS

Palladium-Catalyzed Desulfitative Cross-Coupling Reaction of Sodium Sulfinates with Benzyl Chlorides

(2013) Feng Zhao et al.   ORGANIC LETTERS

Recent Advances in Transition-Metal-Catalyzed Trifluoromethylation and Related Transformations

(2013) Guosheng Liu et al.   SYNTHESIS-STUTTGART

Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP

(2013) Ming-Bo Zhou et al.   Chemical Science

Copper(i)-catalyzed diastereoselective hydroxytrifluoromethylation of dienes accelerated by phosphine ligands

(2013) Deng-Fu Lu et al.   Chemical Science

Palladium-Catalyzed Direct and Site-Selective Desulfitative Arylation of Indoles with Sodium Sulfinates

(2012) Mingyue Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Fluoroform-Derived CuCF3for Low-Cost, Simple, Efficient, and Safe Trifluoromethylation of Aryl Boronic Acids in Air

(2012) Petr Novák et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Trifluoromethylation of Allylsilanes

(2012) Ryo Shimizu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Di- and Trifluoromethylation of α,β-Unsaturated Carboxylic Acids: A Protocol for Vinylic Fluoroalkylations

(2012) Zhengbiao He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Promoted Trifluoromethylation of Primary and Secondary Alkylboronic Acids

(2012) Jun Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ortho-Trifluoromethylation of Functionalized Aromatic Triazenes

(2012) Andreas Hafner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Three-component Oxytrifluoromethylation of Alkenes: Highly Efficient and Regioselective Difunctionalization of CC Bonds Mediated by Photoredox Catalysts

(2012) Yusuke Yasu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Air-Stable Copper Reagent for Nucleophilic Trifluoromethylthiolation of Aryl Halides

(2012) Zhiqiang Weng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates

(2012) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cover Picture: Champagne and Fireworks:Angewandte ChemieCelebrates Its Birthday (Angew. Chem. Int. Ed. 1/2013)

(2012) Peter Gölitz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Free Trifluoromethylaminoxylation of Alkenes

(2012) Yi Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed trifluoromethylation of aryl- and vinylboronic acids with generation of CF3-radicals

(2012) Yang Li et al.   CHEMICAL COMMUNICATIONS

Copper-Catalyzed Nucleophilic Trifluoromethylation of Allylic Halides: A Simple Approach to Allylic Trifluoromethylation

(2012) Yoshihiro Miyake et al.   CHEMISTRY-A EUROPEAN JOURNAL

Trifluoromethylation of Allylsilanes under Copper Catalysis

(2012) Satoshi Mizuta et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxidative Trifluoromethylation of Arylboronates with Shelf-Stable Potassium (Trifluoromethyl)trimethoxyborate

(2012) Bilal A. Khan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal-Free Synthesis of 3,3-Disubstituted Oxoindoles by Iodine(III)-Catalyzed Bromocarbocyclizations

(2012) David C. Fabry et al.   CHEMISTRY-A EUROPEAN JOURNAL

Progress in Copper-Mediated Formation of Trifluoromethylated Arenes

(2012) Tianfei Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkynes and Aryl Boronic Acids Using (Trifluoromethyl)trimethylsilane

(2012) Xueliang Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Desulfitative Arylation by C–O Bond Cleavage of Aryl Triflates with Sodium Arylsulfinates

(2012) Chao Zhou et al.   JOURNAL OF ORGANIC CHEMISTRY

A New Reagent for Direct Difluoromethylation

(2012) Yuta Fujiwara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in the Copper-Catalyzed Trifluoromethylation of Boronic Acids with CF3I

(2012) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Substitution of Primary Allylic Amines with Sulfinate Salts

(2012) Xue-Song Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

(2012) Rong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An efficient tandem elimination–cyclization–desulfitative arylation of 2-(gem-dibromovinyl)phenols(thiophenols) with sodium arylsulfinates

(2012) Wei Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Trifluoromethylation of Aromatic C–H Bond Directed by an Acetamino Group

(2012) Li-Sheng Zhang et al.   ORGANIC LETTERS

Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkenes Using Nucleophilic CF3SiMe3: Efficient C(sp3)–CF3 Bond Formation

(2012) Lingling Chu et al.   ORGANIC LETTERS

Practical Method for the Cu-Mediated Trifluoromethylation of Arylboronic Acids with CF3 Radicals Derived from NaSO2CF3 and tert-Butyl Hydroperoxide (TBHP)

(2012) Yingda Ye et al.   ORGANIC LETTERS

Electrophilic Trifluoromethylation by Copper-Catalyzed Addition of CF3-Transfer Reagents to Alkenes and Alkynes

(2012) Pär G. Janson et al.   ORGANIC LETTERS

A highly efficient palladium-catalyzed desulfitative arylation of azoles with sodium arylsulfinates

(2012) Min Wang et al.   TETRAHEDRON

Trifluoromethylation of heterocycles via visible light photoredox catalysis

(2012) Naeem Iqbal et al.   TETRAHEDRON LETTERS

Oxytrifluoromethylation of multiple bonds using copper catalyst under mild conditions

(2012) Hiromichi Egami et al.   TETRAHEDRON LETTERS

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

(2012) Chao Feng et al.   Chemical Science

Rhenium-Catalyzed Trifluoromethylation of Arenes and Heteroarenes by Hypervalent Iodine Reagents

(2012) Esteban Mejía et al.   ACS Catalysis

Rhodium-Catalyzed Aerobic Coupling between Aldehydes and Arenesulfinic Acid Salts: A Novel Synthesis of Aryl Ketones

(2011) Honghua Rao et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Selective Trifluoromethylation of 1,3-Disubstituted Arenes through Iridium-Catalyzed Arene Borylation

(2011) Tianfei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Strategy for the Perfluoroalkylation of Arenes and Arylbromides by Using Arylboronate Esters and [(phen)CuRF]

(2011) Nichole D. Litvinas et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins

(2011) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Broadly Applicable Copper Reagent for Trifluoromethylations and Perfluoroalkylations of Aryl Iodides and Bromides

(2011) Hiroyuki Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds by Trifluoromethyl Sulfonium Salts

(2011) Cheng-Pan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Oxidative Arylalkylation of Activated Alkenes: Dual CH Bond Cleavage of an Arene and Acetonitrile

(2011) Tao Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-mediated trifluoromethylation of arylboronic acids by trifluoromethyl sulfonium salts

(2011) Cheng-Pan Zhang et al.   CHEMICAL COMMUNICATIONS

A novel catalytic process for trifluoromethylation of bromoaromatic compounds

(2011) Bhupesh S. Samant et al.   CHEMICAL COMMUNICATIONS

Copper-catalyzed trifluoromethylation of aryl boronic acids using a CF3+ reagent

(2011) Jun Xu et al.   CHEMICAL COMMUNICATIONS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Oxidative Trifluoromethylation of Indoles at Room Temperature

(2011) Xin Mu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Catalyzed Trifluoromethylation of Aryl Iodides with Potassium (Trifluoromethyl)trimethoxyborate

(2011) Thomas Knauber et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Desulfitative CH Arylation of Heteroarenes with Sodium Sulfinates

(2011) Bo Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Improved Copper-Mediated Oxidative Trifluoromethylation of Terminal Alkynes

(2011) Ke Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Room Temperature Aryl Trifluoromethylation via Copper-Mediated Oxidative Cross-Coupling

(2011) Todd D. Senecal et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Oxidative Aryltrifluoromethylation of Activated Alkenes at Room Temperature

(2011) Xin Mu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Trifluoromethylation of Terminal Alkenes through Allylic C–H Bond Activation

(2011) Jun Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Cupration of Fluoroform

(2011) Alessandro Zanardi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Direct C–H Oxidative Trifluoromethylation of Heteroarenes

(2011) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Arylation of 1H-Perfluoroalkanes

(2011) Ilya Popov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed C(sp3)–C(sp3) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

(2011) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Palladium-catalyzed desulfitative C–H arylation of azoles with sodium sulfinates

(2011) Ru Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent

(2011) Tianfei Liu et al.   ORGANIC LETTERS

The Palladium-Catalyzed Trifluoromethylation of Vinyl Sulfonates

(2011) Eun Jin Cho et al.   ORGANIC LETTERS

Silver-Mediated Trifluoromethylation of Arenes Using TMSCF3

(2011) Yingda Ye et al.   ORGANIC LETTERS

Pd-Catalyzed Desulfitative Heck Coupling with Dioxygen as the Terminal Oxidant

(2011) Xianya Zhou et al.   ORGANIC LETTERS

Palladium-Catalyzed C–H Perfluoroalkylation of Arenes

(2011) Rebecca N. Loy et al.   ORGANIC LETTERS

Innate C-H trifluoromethylation of heterocycles

(2011) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trifluoromethylation of aryl and heteroaryl halides

(2011) Sudipta Roy et al.   TETRAHEDRON

Iron(III) Chloride-Catalyzed Direct Sulfonylation of Alcohols with Sodium Arenesulfinates

(2010) M. Amarnath Reddy et al.   ADVANCED SYNTHESIS & CATALYSIS

A Facile and Efficient Approach to N-Protected-β-Sulfinyl- enamines via C-Sulfinylation of Enamides and Enecarbamates

(2010) Yinhui Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Transition-Metal-Catalyzed Trifluoromethylation of Aryl Halides

(2010) Rylan J. Lundgren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Mediated Aerobic Oxidative Trifluoromethylation of Terminal Alkynes with Me3SiCF3

(2010) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzedortho-Trifluoromethylation of Arenes Using TFA as a Promoter

(2010) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids

(2010) Lingling Chu et al.   ORGANIC LETTERS

Palladium-Catalyzed Carbo-Heterofunctionalization of Alkenes for the Synthesis of Oxindoles and Spirooxindoles

(2010) Stéphanie Jaegli et al.   ORGANIC LETTERS

A Practical, One-Pot Synthesis of Sulfonylated Pyridines

(2010) Kevin M. Maloney et al.   ORGANIC LETTERS

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Direct C2-trifluoromethylation of indole derivatives catalyzed by copper acetate

(2010) Ryo Shimizu et al.   TETRAHEDRON LETTERS

Oxindole Synthesis by Direct Coupling of C sp 2H and C sp 3H Centers

(2009) Yi-Xia Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aromatic trifluoromethylation catalytic in copper

(2009) Masahiro Oishi et al.   CHEMICAL COMMUNICATIONS

Oxindole synthesis by direct C–H, Ar–H coupling

(2009) Alexis Perry et al.   CHEMICAL COMMUNICATIONS

Iridium-Catalyzed, Regio- and Enantioselective Allylic Substitution with Aromatic and Aliphatic Sulfinates

(2009) Mitsuhiro Ueda et al.   ORGANIC LETTERS

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS