High-Yielding Total Synthesis of Sexually Deceptive Chiloglottones and Antimicrobial Dialkylresorcinols through an Organocatalytic Reductive Coupling Reaction

A gram-scale route to phlegmarine alkaloids: rapid total synthesis of (−)-cermizine B

(2014) Ben Bradshaw et al.   CHEMICAL COMMUNICATIONS

Neighboringortho-Hydroxy Group Directed Catalytic Asymmetric Triple Domino Reactions of Acetaldehyde with (E)-2-(2-Nitrovinyl)phenols

(2014) Dhevalapally B. Ramachary et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Vinylogous Organocatalytic Triple Cascade Reaction: Forging Six Stereocenters in Complex Spiro-Oxindolic Cyclohexanes

(2013) Indranil Chatterjee et al.   ADVANCED SYNTHESIS & CATALYSIS

Formation of 1,3-Cyclohexanediones and Resorcinols Catalyzed by a Widely Occuring Ketosynthase

(2013) Sebastian W. Fuchs et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pot Economy in the Synthesis of Prostaglandin A1and E1Methyl Esters

(2013) Yujiro Hayashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core-Structure-Motivated Design of Iminium-Enolate Organocascade Reactions: Enantioselective Syntheses of 5,6-Dihydroindolizines

(2013) Xianxing Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Floral odour chemistry defines species boundaries and underpins strong reproductive isolation in sexually deceptive orchids

(2013) Rod Peakall et al.   ANNALS OF BOTANY

Organocatalytic Asymmetric Synthesis of Tetracyclic Pyridocarbazole Derivatives by Using a Diels-Alder/aza-Michael/Aldol Condensation Domino Reaction

(2013) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Synthesis of (−)-Oseltamivir and Mechanistic Insights into the Organocatalyzed Michael Reaction

(2013) Takasuke Mukaiyama  et al.   CHEMISTRY-A EUROPEAN JOURNAL

One-Pot Organocatalytic Enantioselective Domino Double-Michael Reaction and Pictet-Spengler–Lactamization Reaction. A Facile Entry to the “Inside Yohimbane” System with Five Contiguous Stereogenic Centers

(2013) Bor-Cherng Hong et al.   ORGANIC LETTERS

Sequential Asymmetric Catalysis in Michael–Michael–Michael–Aldol Reactions: Merging Organocatalysis with Photoredox Catalysis in a One-Pot Enantioselective Synthesis of Highly Functionalized Decalines Bearing a Quaternary Carbon Stereocenter

(2013) Bor-Cherng Hong et al.   ORGANIC LETTERS

Synthesis of Filibuvir. Part III. Development of a Process for the Reductive Coupling of an Aldehyde and a β-Keto-lactone

(2013) Nathan D. Ide et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Enantioselective Organocatalyzed Domino Synthesis of Six-Membered Carbocycles

(2013) Damien Bonne et al.   SYNTHESIS-STUTTGART

Aminocatalytic remote functionalization strategies

(2013) Hao Jiang et al.   Chemical Science

Total Synthesis of Cyrneine A

(2012) Elangovan Elamparuthi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The production of a key floral volatile is dependent on UV light in a sexually deceptive orchid

(2012) Vasiliki Falara et al.   ANNALS OF BOTANY

Discovery of 2-aminobuta-1,3-enynes in asymmetric organocascade catalysis: construction of drug-like spirocyclic cyclohexanes having five to six contiguous stereocenters

(2012) Dhevalapally B. Ramachary et al.   CHEMICAL COMMUNICATIONS

Quadruple Domino Organocatalysis: An Asymmetric Aza-Michael/Michael/Michael/Aldol Reaction Sequence Leading to Tetracyclic Indole Structures with Six Stereocenters

(2012) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identification of the First Alkenyl Chiloglottone Congener

(2012) Jacqueline Poldy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Assembly of Spirooxindole Derivatives via Organocatalytic Iminium-Enamine Cascade Reactions

(2012) Klaus Albertshofer et al.   ORGANIC LETTERS

Assembly of Spirooxindole Derivatives Containing Four Consecutive Stereocenters via Organocatalytic Michael–Henry Cascade Reactions

(2012) Klaus Albertshofer et al.   ORGANIC LETTERS

Tandem Cyclization of α-Cyano α-Alkynyl Aryl Ketones Induced by tert-Butyl Hydroperoxide and Tetrabutylammonium Iodide

(2012) Ying-Chieh Wong et al.   ORGANIC LETTERS

One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether

(2011) Hayato Ishikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Asymmetric Organocatalytic One-Pot Strategy to Octahydroacridines

(2011) Gustav Dickmeiss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nature-inspired cascade catalysis: reaction control through substrate concentration—double vs. quadruple domino reactions

(2011) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

Dienamine Catalysis: An Emerging Technology in Organic Synthesis

(2011) Dhevalapally B. Ramachary et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Multistep Synthesis Featuring Classic Carbonyl Chemistry for the Advanced Organic Chemistry Laboratory

(2011) David B. Duff et al.   JOURNAL OF CHEMICAL EDUCATION

Cyclopentane-1,3-dione: A Novel Isostere for the Carboxylic Acid Functional Group. Application to the Design of Potent Thromboxane (A2) Receptor Antagonists

(2011) Carlo Ballatore et al.   JOURNAL OF MEDICINAL CHEMISTRY

Total Synthesis of Optically Active Lycopladine A by Utilizing Diastereoselective Protection of Carbonyl Group in a 1,3-Cyclohexanedione Derivative

(2011) Kou Hiroya et al.   JOURNAL OF ORGANIC CHEMISTRY

Design, synthesis and biological evaluation of optically pure functionalized spiro[5,5]undecane-1,5,9-triones as HIV-1 inhibitors

(2011) Dhevalapally B. Ramachary et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Generation of Medium-Ring Cycloalkynes by Ring Expansion of Vinylogous Acyl Triflates

(2011) Jumreang Tummatorn et al.   ORGANIC LETTERS

One-pot multistep synthesis of 3-aminoindolizine derivatives

(2011) Lianhai Li et al.   TETRAHEDRON LETTERS

Organocatalytic asymmetric synthesis of polyfunctionalized 3-(cyclohexenylmethyl)-indoles via a quadruple domino Friedel–Crafts-type/Michael/Michael/aldol condensation reaction

(2010) Dieter Enders et al.   CHEMICAL COMMUNICATIONS

General Approach to 2,3-Dibenzyl-γ-butyrolactone Lignans: Application to the Total Synthesis of (±)-5′-Methoxyyatein, (±)-5′-Methoxyclusin, and (±)-4′-Hydroxycubebinone

(2010) Prashanth K. Amancha et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric organocatalysis in total synthesis – a trial by fire

(2010) Eugenia Marqués-López et al.   NATURAL PRODUCT REPORTS

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Pollinator specificity, floral odour chemistry and the phylogeny of Australian sexually deceptive Chiloglottis orchids: implications for pollinator-driven speciation

(2010) Rod Peakall et al.   NEW PHYTOLOGIST

Sequential one-pot combination of multi-component and multi-catalysis cascade reactions: an emerging technology in organic synthesis

(2010) Dhevalapally B. Ramachary et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Total Synthesis of (+)-Conicol via Cascade Three-Component Organocatalysis

(2010) Bor-Cherng Hong et al.   ORGANIC LETTERS

Asymmetric Quadruple Aminocatalytic Domino Reactions to Fused Carbocycles Incorporating a Spirooxindole Motif

(2010) Kun Jiang et al.   ORGANIC LETTERS

One-Pot Enantioselective Syntheses of Iminosugar Derivatives Using Organocatalyticanti-Michael−anti-Aza-Henry Reactions

(2010) Ritsuo Imashiro et al.   ORGANIC LETTERS

Facile synthesis of asymmetric quaternary centers based on diastereoselective protection of the carbonyl group at the symmetrical position

(2010) Kou Hiroya et al.   TETRAHEDRON LETTERS

Synthetic studies toward the PPAP natural products, prolifenones A and B and hyperforin: an Effenberger cyclization approach

(2010) Goverdhan Mehta et al.   TETRAHEDRON LETTERS

The organocatalytic three-step total synthesis of (+)-frondosin B

(2010) Maud Reiter et al.   Chemical Science

Cycle-Specific Organocascade Catalysis: Application to Olefin Hydroamination, Hydro-oxidation, and Amino-oxidation, and to Natural Product Synthesis

(2009) Bryon Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-Yielding Synthesis of the Anti-Influenza Neuramidase Inhibitor (−)-Oseltamivir by Three “One-Pot” Operations

(2009) Hayato Ishikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Four-Component Quadruple Domino Reaction Initiated by Oxa-Michael Addition of Alcohols to Acrolein

(2009) Fang-Lin Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Development of Diastereoselective Birch Reduction−Alkylation Reactions of Bi- and Tricyclic β-Alkoxy-α,β-unsaturated Ketones

(2009) Kou Hiroya et al.   JOURNAL OF ORGANIC CHEMISTRY

A General Approach to Chiral Building Blocks via Direct Amino Acid-Catalyzed Cascade Three-Component Reductive Alkylations: Formal Total Synthesis of HIV-1 Protease Inhibitors, Antibiotic Agglomerins, Brefeldin A, and (R)-γ-Hexanolide

(2009) Dhevalapally B. Ramachary et al.   JOURNAL OF ORGANIC CHEMISTRY

Nine-Step Enantioselective Total Synthesis of (+)-Minfiensine

(2009) Spencer B. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of chiloglottones – semiochemicals from sexually deceptive orchids and their pollinators

(2009) Jacqueline Poldy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The discovery of 2,5-dialkylcyclohexan-1,3-diones as a new class of natural products

(2009) S. Franke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organocatalytic Asymmetric Triple Domino Reactions of Nitromethane with α,β-Unsaturated Aldehydes

(2009) Dieter Enders et al.   SYNLETT

Asymmetric Synthesis of Polyfunctionalized Mono-, Bi-, and Tricyclic Carbon Frameworksvia Organocatalytic Domino Reactions

(2008) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

A Short Route to α‐Tocopherol

(2008) Kegang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric α-Aminoxylation/Aza-Michael Reactions for the Synthesis of Functionalized Tetrahydro-1,2-oxazines

(2008) Min Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Domino Reactions: A Cascade Consisting of a Michael Addition and an Aldehyde α-Alkylation

(2008) Dieter Enders et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Aminosulfenylation of α,β-Unsaturated Aldehydes

(2008) Gui-Ling Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Alkaloid Synthesis: A One-Pot Organocatalytic Reaction to Quinolizidine Derivatives

(2008) Johan Franzén et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expeditious Total Syntheses of Camptothecin and 10-Hydroxycamptothecin

(2008) Guan-Sai Liu et al.   ORGANIC LETTERS

Pheromones and analogs from Neozeleboria wasps and the orchids that seduce them: a versatile synthesis of 2,5-dialkylated 1,3-cyclohexanediones

(2008) Jacqueline Poldy et al.   TETRAHEDRON LETTERS

Enantioselective synthesis of the tetrahydro-6H-benzo[c]chromenes via Domino Michael–Aldol condensation: control of five stereocenters in a quadruple-cascade organocatalytic multi-component reaction

(2008) Prakash Kotame et al.   TETRAHEDRON LETTERS

Organocatalysis Lost: Modern Chemistry, Ancient Chemistry, and an Unseen Biosynthetic Apparatus

(2007) Carlos F. Barbas   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of Pharmaceutical Drugs, Drug Intermediates and Ingredients by Using Direct Organo-Click Reactions

(2007) Dhevalapally B. Ramachary et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY