Article
Chemistry, Multidisciplinary
Chun Zhang, Man Yang, Yanjie Qiu, Meijun Song, Hongyan Wang, Min Yang, Wenlin Xie, Jie Wu, Shengqing Ye
Summary: This paper presents a new method for the synthesis of alkoxysulfonyl radical species through electrochemical anodic oxidation of inorganic sulfites with alcohols. These radicals can be utilized in alkene difunctionalization reaction to provide various sulfonate esters.
Review
Chemistry, Organic
Padinjare Veetil Saranya, Mohan Neetha, C. M. A. Afsina, Gopinathan Anilkumar
Summary: Multicomponent reactions (MCRs) can form highly functionalized compounds through the reaction between three or more reactants in a one-pot manner, providing products with the utilization of lesser resources and energy. MCRs adhere to the principles of green chemistry and have diverse applications across various fields.
CURRENT ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Maximilian Sender, Fabian L. Huber, Maximilian C. G. Moersch, Daniel Kowalczyk, Julian Hniopek, Sarah Klingler, Michael Schmitt, Simon Kaufhold, Kevin Siewerth, Juergen Popp, Boris Mizaikoff, Dirk Ziegenbalg, Sven Rau
Summary: This work elaborates on the effect of dynamic irradiation on light-driven molecular water oxidation and emphasizes the importance of overall reaction engineering in overcoming limiting factors. By controlling the local availability of photons, the overall catalytic efficiency can be significantly enhanced.
Review
Polymer Science
Olga V. Filippova, Aleksey V. Maksimkin, Tarek Dayyoub, Dmitry I. Larionov, Dmitry V. Telyshev
Summary: Elastomeric materials, such as polyurethanes, silicones, and acrylic elastomers, are commonly used in actuator design and soft robot development due to their outstanding properties. However, conventional synthetic methods used to produce these materials may have negative environmental and health impacts. Therefore, the development of new synthetic routes using green chemistry principles and the synthesis of elastomers from renewable bioresources are important steps towards creating sustainable and biocompatible materials. This review aims to address existing approaches to green synthesis of elastomers, compare their properties with traditional materials, and analyze their feasibility for actuators. Moreover, it discusses the advantages, challenges, and future prospects of green elastomer synthesis.
Article
Chemistry, Organic
Zhichao Wang, Shoko Yamazaki, Yuji Mikata, Miho Oba, Hiroshi Takashima, Tsumoru Morimoto, Akiya Ogawa
Summary: Intramolecular cycloaddition reactions of α-bromostyr-ene-functionalized amides have been investigated, resulting in the formation of 1,4-dihydronaphthalenes and naphthalene derivatives under suitable reaction conditions. The mechanisms of these reactions may involve the intervention of molecular oxygen and subsequent radical reactions.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Tim van Lingen, Valentina Bragoni, Marco Dyga, Benjamin Exner, Daniel Schick, Christoph Held, Gabriele Sadowski, Lukas J. Goossen
Summary: This study addresses the challenge of salt waste formation in C-H carboxylations, which hinders the use of CO2 as a C-1 building block in industrial synthesis. Through a circular process, dimethyl succinate, a C-4 base chemical, is produced from CO2 and acetylene. Increased CO2 pressure allows for reversible acidification and esterification of the succinate salt, while the cesium base and hydrogenation catalyst are regenerated for reuse. Thermodynamic modeling reveals the origins of the reversible acidity switch and the crucial roles of the cesium base and NMP/MeOH solvents.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Chemistry, Analytical
Meiyun Shi, Xinyue Zheng, Ning Zhang, Yufeng Guo, Meichen Liu, Lei Yin
Summary: Green analytical chemistry (GAC) is a concept widely recognized in analytical chemistry laboratories that promotes the use of energy-saving instruments, reduction of toxic agents, and minimal waste production. This article introduces and discusses 16 typical greenness metric tools, such as the National Environmental Methods Index (NEMI), Analytical Eco-scale, Analytical method volume intensity (AMVI), Green Analytical Procedure Index (GAPI), and Analytical Greenness Calculator (AGREE), including their criteria, characteristics, advantages, disadvantages, and applications. The aim is to help analysts assess the greenness of different analytical procedures using various metric tools.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Mohamed Madani, Shimaa Hosny, Dalal Mohamed Alshangiti, Norhan Nady, Sheikha A. Alkhursani, Huda Alkhaldi, Samera Ali Al-Gahtany, Mohamed Mohamady Ghobashy, Ghalia A. Gaber
Summary: This study presents an outline of the 12 principles of green relevance in nanomaterial synthesis, emphasizing the importance of using green renewable resources to protect the environment. It introduces several main directions, such as the choice of innocuous solvents, the use of additives, alternative reaction circumstances, and the development of energy-efficient synthetic methods. These green resource routes play a crucial role in nanotechnology applications, such as green energy.
NANOTECHNOLOGY REVIEWS
(2022)
News Item
Chemistry, Multidisciplinary
Jun-Jie Chen, Huan-Ming Huang
Summary: In this study, a new strategy using N2O as the oxygen source under mild conditions was developed for the conversion of aryl halides to phenols.
Article
Chemistry, Multidisciplinary
Siyu Zhang, Yipin Zhu, Xiang Li, Shengjie Chen, Yu Chen, Hui He, Bo Peng, Yan Zhang
Summary: This experiment involves a one-pot multicomponent synthesis to prepare an unsymmetrical indole-substituted methane derivative using two consecutive reactions. It was conducted by second-year undergraduate chemistry students in a laboratory classroom. The experiment offers students an opportunity to perform novel organic chemistry transformations and synthesize complex molecules from simple substrates. The experiment has several noteworthy features, including multicomponent synthesis, good operability, absence of catalyst and additives, high yield and atomic economy, and the use of inexpensive and green solvent. It also incorporates various analytical techniques such as TLC, NMR, and IR analysis, and discusses important concepts such as green chemistry, chem- and regioselectivity, conjugated 1,4-addition, and atomic economy.
JOURNAL OF CHEMICAL EDUCATION
(2023)
Article
Engineering, Environmental
Chenghao Zhang, Jing Luo, Binqi Xie, Wei Liu, Jisong Zhang
Summary: A continuous micro-packed bed reactor platform is developed to determine the kinetics of aerobic ethylbenzene oxidation in the presence of N-hydroxyphthalimide. The reactor system offers enhanced gas-liquid mass transfer, leading to a significant increase in the space-time yield of ethylbenzene oxidation compared to traditional batch reactors. Furthermore, the organic catalyst NHPI is covalently anchored on commercial activated carbon through an imidization reaction. The synthesized heterogeneous catalysts exhibit excellent performance in terms of acetophenone yield and turnover frequency (TOF).
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Nilanjana Mukherjee, Tanmay Chatterjee
Summary: This study discloses a metal-free, iodine-catalyzed oxidative C-H sulfenylation and selenation of alkenes in water, which provides a cost-effective, highly atom-economical, and sustainable synthesis method for valuable vinyl sulfides and selenides, including some aggregation-induced-emission (AIE) active molecules. The method shows several advantages, such as the use of inexpensive reagents, water as the reaction medium, high reaction efficiency, and excellent green chemistry metrics.
Article
Chemistry, Organic
Jeremy R. Tuck, Robert J. Tombari, Noah Yardeny, David E. Olson
Summary: In this study, arylazo-1,2,3-triazoles were successfully synthesized using azide-alkyne click chemistry, showcasing high thermal stabilities and near-quantitative bidirectional photoconversion.
Review
Biochemistry & Molecular Biology
Cecilia Scimmi, Luca Sancineto, Jozef Drabowicz, Claudio Santi
Summary: This article provides a detailed overview of oxidative depolymerization of lignin and biomass valorization. It compares the advantages and disadvantages of different methods, highlights the green aspects, and gives an overview of selenium catalyzed lignin valorization.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Organic
Katarina L. Keel, Jetze J. Tepe
Summary: The study presents the first total synthesis of Nortopsentin D, involving a pivotal condensation and subsequent cyclization of amidine and dione via a pinacol-like rearrangement. This unique synthetic strategy is significant for the formation of 5,5-disubstituted (4H)-imidazol-4-one containing natural products.
Article
Chemistry, Physical
Gabriel M. Vieira, Artur V. Granato, Elena V. Gusevskaya, Eduardo N. dos Santos, Pierre H. Dixneuf, Cedric Fischmeister, Christian Bruneau
APPLIED CATALYSIS A-GENERAL
(2020)
Article
Chemistry, Applied
Niklas Zwettler, Antoine Dupe, Sumea Klokic, Angela Milinkovic, Dado Rodic, Simon Walg, Dmytro Neshchadin, Ferdinand Belaj, Nadia C. Moesch-Zanetti
ADVANCED SYNTHESIS & CATALYSIS
(2020)
Review
Chemistry, Physical
Hallouma Bilel, Naceur Hamdi, Cedric Fischmeister, Christian Bruneau
Article
Chemistry, Organic
Harikrishnan Jayaprakash, Liwei Guo, Shengdong Wang, Christian Bruneau, Cedric Fischmeister
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Review
Chemistry, Inorganic & Nuclear
Rafael Gramage-Doria, Christian Bruneau
Summary: Ruthenium complexes are widely recognized as excellent pre-catalysts for challenging C-H bond functionalization reactions, and their combination with other types of chemical reactions can reduce purification and isolation steps, increasing reaction sustainability. Research in this field focuses on the compatibility of different reaction sequences, with a particular emphasis on the compatibility of ruthenium-catalyzed C-H bond functionalization with organic transformations, metal-mediated reactions, and transition metal catalysis.
COORDINATION CHEMISTRY REVIEWS
(2021)
Editorial Material
Chemistry, Inorganic & Nuclear
Jean-Francois Soule, Christian Bruneau, Christophe Darcel
Review
Chemistry, Multidisciplinary
Salekh M. Masoud, Dania V. Vorobyeva, Dmitry A. Petropavlovskikh, Christian Bruneau, Sergey N. Osipov
Summary: This review summarizes literature data on methods for introducing fluorine atoms and fluoralkyl groups into different ligands to construct metathesis-active ruthenium carbene complexes, analyzing their influence on catalytic activity. The choice of fluorinated substituents in NHC ligands aims to increase ruthenium atom electrophilicity and enhance complex activity; introducing polyfluoroalkyl groups can help solve the issue of catalyst recovery.
RUSSIAN CHEMICAL REVIEWS
(2021)
Article
Chemistry, Physical
Luciana Sarmento Fernandes, Dalmo Mandelli, Wagner A. Carvalho, Elsa Caytan, Cedric Fischmeister, Christian Bruneau
Summary: The direct functionalization of sterically demanding alpha,alpha-disubstituted double bonds in beta-pinene, (-)-limonene and (-)-limonene terpenoids has been achieved through cross metathesis with internal olefins. This clean transformation provides a new method for accessing functionalized bulky cyclic terpenes, where the terminal double bond generates a trisubstituted olefin.
APPLIED CATALYSIS A-GENERAL
(2021)
Article
Chemistry, Multidisciplinary
Angela Milinkovic, Antoine Dupe, Ferdinand Belaj, Nadia C. Moesch-Zanetti
Summary: Molybdenum(VI) bis(imido) complexes with frustrated Lewis pair characteristics can heterolytically split H-H, Si-H, and O-H bonds. These complexes can be used as catalysts for the hydrosilylation reaction. Mechanistic elucidation revealed the insertion of aldehydes into the B-H bond of the molybdenum complexes, highlighting the weakly coordinating cation behavior of molybdenum.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Thalita S. Galhardo, Anderson K. Ueno, Thais A. Costa-Silva, Andre G. Tempone, Wagner A. Carvalho, Cedric Fischmeister, Christian Bruneau, Dalmo Mandelli, Joao Henrique G. Lago
Summary: In this study, compounds isolated from N. leucantha were used as starting material to synthesize two new derivatives, which showed activity against trypanosome and no toxicity to mammalian cells. Mechanism study revealed that the derivatives caused depolarization of the parasite's plasma membrane and collapse of mitochondrial membrane potential. Therefore, this compound could be a potential candidate for future drug design in the treatment of Chagas disease.
CHEMICO-BIOLOGICAL INTERACTIONS
(2022)
Article
Chemistry, Physical
Thalita S. Galhardo, Anderson K. Ueno, Wagner A. Carvalho, Thais A. Costa-Silva, Marina M. Goncalves, Mariana B. Abiuzi, Andre G. Tempone, Joao Henrique G. Lago, Dalmo Mandelli, Cedric Fischmeister, Christian Bruneau
Summary: Ruthenium-catalyzed cross metathesis of biseugenol with electron-deficient olefins resulted in the synthesis of derivatives 3a-3e in good yields and excellent conversion rates. The antitrypanosomal activity of these compounds against Trypanosoma cruzi was evaluated, and compounds 3b and 3d showed similar IC50 values to biseugenol, but with reduced toxicities and similar selectivity indexes to the standard drug benznidazol.
Article
Chemistry, Physical
Naba Abuhafez, Herve Ruffin, Raghu Kamaraj, Christian Bruneau, Rafael Gramage-Doria
Summary: A new method for the synthesis of 1,3-diene building blocks using ruthenium-catalyzed oxidative homo- and cross-coupling is reported, which mainly produces the E,E isomer. This methodology also allows for the synthesis of adipic acid ester derivatives in a one-pot fashion after in situ ruthenium-catalyzed hydrogenation.
CATALYSIS SCIENCE & TECHNOLOGY
(2021)
