Article
Multidisciplinary Sciences
Lisa Dowling, Philip Jakeman, Catherine Norton, Maeve M. Skelly, Hamid Yousuf, Miranda G. Kiernan, Margaret Toomey, Sheila Bowers, Suzanne S. Dunne, J. Calvin Coffey, Colum P. Dunne
Summary: Crohn's disease is a global inflammatory bowel condition that differs from healthy population in terms of body fat distribution, specifically showing elevated gynoid fat and reduced android fat. There is a potential rationale to refer to Crohn's disease as a fatty intestine condition, similar to fatty liver conditions, which may require further investigation in a larger patient cohort.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Debora Basile, Michele Bartoletti, Maurizio Polano, Lucia Bortot, Lorenzo Gerratana, Paola Di Nardo, Matteo Borghi, Valentina Fanotto, Giacomo Pelizzari, Camilla Lisanti, Mattia Garutti, Silvia Buriolla, Elena Ongaro, Eva Andreuzzi, Marcella Montico, Luca Balestreri, Gianmaria Miolo, Giuseppe Toffoli, Giuseppe Aprile, Fabio Puglisi, Angela Buonadonna
Summary: This study investigated the prognostic role of adiposity, especially visceral fat, in patients with metastatic colorectal cancer. The results showed that higher visceral fat values were associated with worse outcomes in these patients. Further research is needed to explore the impact of visceral fat on colorectal cancer patients.
CLINICAL NUTRITION
(2021)
Article
Multidisciplinary Sciences
Yuki Komatsu, Kiyoshi Aoyama, Mamoru Yoneda, Shogo Ito, Yusuke Sano, Yumeno Kawai, Xixi Cui, Yuichiro Yamada, Nozomi Furukawa, Katsuhide Ikeda, Kohzo Nagata
Summary: The removal of interscapular brown adipose tissue (iBAT) attenuated the exacerbation of cardiac inflammation and fibrosis induced by salt loading in DS/obese rats, but did not affect the development of hypertension. Salt loading led to adipocyte hypertrophy and increased inflammation in white adipose tissue, while the conversion of iBAT to white adipose tissue-like tissue contributed to elevated levels of circulating interleukin-6, exacerbating cardiac pathology.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2021)
Article
Endocrinology & Metabolism
Eloi Gagnon, Patricia L. Mitchell, Benoit J. Arsenault
Summary: In this bidirectional Mendelian randomization study, it was found that abdominal adiposity may be a key determinant of circulating insulin levels, while insulin secretion may promote peripheral adipose tissue accumulation.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Biochemistry & Molecular Biology
Xuan Song, Hongxia Wu, Wenhua Zhang, Bei Wang, Hongjun Sun
Summary: This study aimed to construct a prediction equation for estimating visceral adipose tissue (VAT) mass using anthropometric parameters and validate it with a validation group. The results showed that the prediction equations with age, sex, height, BMI, weight, TG, HDL, and grade of hepatic steatosis were strongly correlated with VAT mass. The equations could be valuable tools for predicting VAT mass when dual X-ray absorptiometry (DXA) is unavailable.
LIPIDS IN HEALTH AND DISEASE
(2022)
Article
Nutrition & Dietetics
Ming Kong, Manman Xu, Ying Zhou, Nan Geng, Ning Lin, Wenyan Song, Shanshan Li, Yuetong Piao, Zuoqing Han, Rong Guo, Chao Yang, Nan Luo, Zhong Wang, Lei Ma, Quanxiao Xu, Lili Wang, Wanchun Qiu, Junfeng Li, Daimeng Shi, Eddie C. Cheung, Rongkuan Li, Yu Chen, Zhongping Duan
Summary: This study analyzed the distribution of abdominal adipose tissue in a healthy population in northern China using abdominal CT scans. The results showed significant differences in abdominal fat distribution between men and women, with a high proportion of visceral obesity even in individuals with normal BMI.
FRONTIERS IN NUTRITION
(2022)
Article
Surgery
Nghiem B. Ha, Aldo J. Montano-Loza, Elizabeth J. Carey, Shezhang Lin, Amy M. Shui, Chiung-Yu Huang, Michael A. Dunn, Jennifer C. Lai
Summary: This study aims to investigate the association between sarcopenic visceral obesity (SVO) and post-transplant mortality. Through analysis of patients with cirrhosis, it was found that SVO is significantly associated with increased post-transplant mortality.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Cell Biology
Pernille Heimdal Holm, Louise Hindso, Kristine Boisen Olsen, Jytte Banner
Summary: The study explores the associations between obesity, myocardial fat, visceral adipose tissue, and cardiovascular disease. It finds that myocardial fat is correlated with obesity and epicardial adipose tissue, but not with waist-hip ratio or visceral adipose tissue measures. The findings suggest that myocardial fat plays a role in cardiovascular health, particularly in the right ventricle.
Article
Hematology
Eric K. Broni, Oluseye Ogunmoroti, Renato Quispe, Ty Sweeney, Bhavya Varma, Oluwaseun E. Fashanu, Pamela L. Lutsey, Matthew Allison, Moyses Szklo, Chiadi E. Ndumele, Erin D. Michos
Summary: Obesity leads to adipocyte hypertrophy and adipokine dysregulation and is an independent risk factor for venous thromboembolism (VTE). However, the association between adipokines and VTE is not well established. This study aimed to examine whether adipokines are associated with increased risk of incident VTE. The findings showed that higher resistin levels were independently associated with greater risk of incident VTE.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Nutrition & Dietetics
Ana Teresa Limon-Miro, Mauro E. Valencia, Veronica Lopez-Teros, Heliodoro Aleman-Mateo, Rosa O. Mendez-Estrada, Bertha Pacheco-Moreno, Humberto Astiazaran-Garcia
Summary: The study evaluated the effect of a 6-month individualized food-based nutrition intervention program on the body composition of breast cancer patients during treatment. The program was found to effectively reduce body weight, fat mass, fat mass index, visceral and abdominal fat, while preserving skeletal muscle mass.
CLINICAL NUTRITION
(2021)
Article
Cardiac & Cardiovascular Systems
Fleur L. Meulmeester, Jiao Luo, Leon G. Martens, Nadia Ashrafi, Renee de Mutsert, Dennis O. Mook-Kanamori, Hildo J. Lamb, Frits R. Rosendaal, Ko Willems van Dijk, Kevin Mills, Diana van Heemst, Raymond Noordam
Summary: This study found that excess abdominal fat in middle-aged individuals is associated with lower levels of oxidized α-TOH metabolites. This suggests lower vitamin E antioxidative activity in individuals with higher abdominal fat.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
Georgia Colleluori, Laura Graciotti, Mauro Pesaresi, Angelica Di Vincenzo, Jessica Perugini, Eleonora Di Mercurio, Sara Caucci, Patrizia Bagnarelli, Cristina M. Zingaretti, Enzo Nisoli, Stefano Menzo, Adriano Tagliabracci, Annie Ladoux, Christian Dani, Antonio Giordano, Saverio Cinti
Summary: This study confirms the presence of lung fat embolism in COVID-19 patients and describes novel COVID-19-related features possibly contributing to the unfavorable prognosis in individuals with COVID-19 and obesity.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Article
Multidisciplinary Sciences
Keiichiro Shimoyama, Akira Endo, Takashi Shimazui, Takashi Tagami, Kazuma Yamakawa, Mineji Hayakawa, Takayuki Ogura, Atsushi Hirayama, Hideo Yasunaga, Jun Oda
Summary: This study aimed to determine if obesity is associated with disease outcomes in critically ill COVID-19 patients requiring mechanical ventilation. The study included Japanese registry data of COVID-19 patients who required invasive mechanical ventilation and were discharged between January and September 2020. The findings showed that obesity was not significantly associated with in-hospital mortality or VV-ECMO implementation in these patients.
SCIENTIFIC REPORTS
(2023)
Article
Endocrinology & Metabolism
Hanying Liu, Di Yang, Shaobo Li, Yunfeng Xiao, Yinfang Tu, Danfeng Peng, Yuqian Bao, Junfeng Han, Haoyong Yu
Summary: A simple model to predict VFA using age, waist circumference, and neck circumference was developed and validated in overweight and obese Chinese individuals, demonstrating good predictive power for both men and women. The equations provide an ideal tool for early detection of visceral obesity.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Kai Wang, Minggang Deng, Jinyi Wu, Lingli Luo, Rui Chen, Fang Liu, Jiaqi Nie, Fengxi Tao, Qingwen Li, Xin Luo, Fang Xia
Summary: This study explores the association between the oxidative balance score (OBS) and the percentages of total abdominal fat mass (TAFM) and visceral adipose tissue mass (VATM) in young and middle-aged US adults. The findings suggest that higher OBS is correlated with lower risks of abdominal obesity and visceral fat accumulation.
FRONTIERS IN NUTRITION
(2023)
Article
Statistics & Probability
Jitka Machalova, Renata Talska, Karel Hron, Ales Gaba
Summary: This paper introduces a method for representing probability density functions as real functions in functional data analysis, which leads to the construction of a new class of spline functions called compositional splines. The use of this new tool for statistical processing of densities is demonstrated in a case of simplicial functional principal component analysis with anthropometric data.
COMPUTATIONAL STATISTICS
(2021)
Article
Geriatrics & Gerontology
Izabela Zajac-Gawlak, Jana Pelclova, Dorota Groffik, Miroslava Pridalova, Agnieszka Nawrat-Szoltysik, Aleksandra Kroemeke, Ales Gaba, Ewa Sadowska-Krepa
Summary: This longitudinal study suggests that meeting step-based guidelines or increasing daily steps may be associated with a lower risk of MetS, specifically in concentrations of HDL-C and TG. These findings could help in designing interventions to decrease the risk of MetS in older women.
Article
Public, Environmental & Occupational Health
Ales Gaba, Jan Dygryn, Nikola Stefelova, Lukas Rubin, Karel Hron, Lukas Jakubec
Summary: Little is known about how context-specific sedentary behaviors affect adiposity. This study found significant associations between out-of-school sedentary behaviors and adiposity in both boys and girls. Replacing out-of-school sedentary behaviors with light physical activity led to decreases in fat mass percentage and fat mass index in girls, highlighting the importance of reducing sedentary behaviors outside of school for preventing childhood obesity.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2021)
Review
Public, Environmental & Occupational Health
Eliska Materova, Jana Pelclova, Ales Gaba, Karel Fromel
Summary: This study provides an overview of the available evidence on physical activity and sedentary behavior in Czech children and adolescents. The majority of the articles were cross-sectional and focused on specific areas of physical activity. Future research should prioritize longitudinal designs, interventions, and the use of mixed methods for assessment.
Article
Environmental Sciences
Stuart J. Fairclough, Liezel Hurter, Dorothea Dumuid, Ales Gaba, Alex Rowlands, Borja del Pozo Cruz, Ashley Cox, Matteo Crotti, Lawrence Foweather, Lee E. F. Graves, Owen Jones, Deborah A. McCann, Robert J. Noonan, Michael B. Owen, James R. Rudd, Sarah L. Taylor, Richard Tyler, Lynne M. Boddy
Summary: This study examined the associations between acceleration intensity bands and body mass index (BMI) z-score in youth. The findings showed that the >= 700 mg intensity band was strongly and inversely associated with BMI z-score. Reallocation of time between intensity bands resulted in clinically meaningful differences in BMI z-score.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Sport Sciences
Ales Gaba, Petr Badura, Michal Vorlicek, Jan Dygryn, Zdenek Hamrik, Michal Kudlacek, Lukas Rubin, Erik Sigmund, Dagmar Sigmundova, Jana Vasickova
JOURNAL OF EXERCISE SCIENCE & FITNESS
(2022)
Article
Public, Environmental & Occupational Health
Salome Aubert, Joel D. Barnes, Iryna Demchenko, Myranda Hawthorne, Chalchisa Abdeta, Patrick Abi Nader, Jose Carmelo Adsuar Sala, Nicolas Aguilar-Farias, Susana Aznar, Peter Bakalar, Jasmin Bhawra, Javier Brazo-Sayavera, Mikel Bringas, Jonathan Y. Cagas, Angela Carlin, Chen-Kang Chang, Bozhi Chen, Lars Breum Christiansen, Candice Jo-Anne Christie, Gabriela Fernanda De Roia, Christine Delisle Nystrom, Yolanda Demetriou, Visnja Djordjic, Arunas Emeljanovas, Liri Findling Endy, Ales Gaba, Karla I. Galaviz, Silvia A. Gonzalez, Kylie D. Hesketh, Wendy Yajun Huang, Omphile Hubona, Justin Y. Jeon, Danijel Jurakic, Jaak Jurimae, Tarun Reddy Katapally, Piyawat Katewongsa, Peter T. Katzmarzyk, Yeon-Soo Kim, Estelle Victoria Lambert, Eun-Young Lee, Sharon Levi, Pablo Lobo, Marie Lof, Tom Loney, Jose Francisco Lopez-Gil, Juan Lopez-Taylor, Evelin Maestu, Agus Mahendra, Daga Makaza, Marla Frances T. Mallari, Taru Manyanga, Bojan Masanovic, Shawnda A. Morrison, Jorge Mota, Falk Mueller-Riemenschneider, Laura Munoz Bermejo, Marie H. Murphy, Rowena Naidoo, Phuong Nguyen, Susan Paudel, Zeljko Pedisic, Jorge Perez-Gomez, John J. Reilly, Anne Kerstin Reimers, Amie B. Richards, Diego Augusto Santos Silva, Pairoj Saonuam, Olga L. Sarmiento, Vedrana Sember, Mohd Razif Shahril, Melody Smith, Martyn Standage, Gareth Stratton, Narayan Subedi, Tuija H. Tammelin, Chiaki Tanaka, Riki Tesler, David Thivel, Dawn Mahube Tladi, Lenka Tlucakova, Leigh M. Vanderloo, Alun Williams, Stephen Heung Sang Wong, Ching-Lin Wu, Pawel Zembura, Mark S. Tremblay
Summary: The Global Matrix 4.0 provides a comprehensive understanding of global physical activity levels among children and adolescents. The study reveals low levels of physical activity globally and highlights the potential impact of factors like the COVID-19 pandemic, conflicts, climate change, and economic changes.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2022)
Article
Statistics & Probability
Nikola Stefelova, Javier Palarea-Albaladejo, Karel Hron, Ales Gaba, Jan Dygryn
Summary: Movement behaviour data are compositional in nature, and the logratio methodology is suitable for their statistical analysis. The introduction of pivoting balances and the use of ternary diagrams facilitate the construction, interpretation, and visualization of time-use compositions. The proposed method is illustrated in a study examining the relationship between movement behaviours and adiposity in Czech school-aged girls, suggesting the importance of achieving a positive balance of physical activity and sleep for obesity prevention.
COMPUTATIONAL STATISTICS
(2023)
Article
Nutrition & Dietetics
Victor Segura-Jimenez, Zeljko Pedisic, Ales Gaba, Dorothea Dumuid, Timothy Olds, Nikola Stefelova, Karel Hron, Sonia Gomez-Martinez, Ascension Marcos, Jose Castro-Pinero
Summary: The aim of the study was to explore the associations between longitudinal reallocations of time between different movement behaviours and changes in inflammatory markers in children and adolescents. The results showed that reallocating time from sedentary behaviour to sleep was associated with increases in C3 levels, reallocating time from light physical activity to sleep was associated with increases in C3 levels, reallocating time from light physical activity to other time-use components was associated with increases in C4 levels, and any reallocation of time away from moderate-to-vigorous physical activity was associated with unfavourable changes in leptin levels.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2023)
Article
Multidisciplinary Sciences
David Janda, Ales Gaba, Ondrej Vencalek, Stuart Fairclough, Jan Dygryn, Lukas Jakubec, Lukas Rubin
Summary: This study analyzed the differences in 24-hour activity profiles between school days and weekend days, and investigated the associations between unfavorable activity profiles and childhood obesity. The results showed that activity levels were lower on weekend days and positively associated with obesity indicators. This highlights the importance of optimizing 24-hour movement behaviors in preventing childhood obesity.
Article
Health Care Sciences & Services
Paulina Jaskova, Javier Palarea-Albaladejo, Ales Gaba, Dorothea Dumuid, Zeljko Pedisic, Jana Pelclova, Karel Hron
Summary: The distribution of time spent in physical activity of various intensities has significant implications for health. Using a compositional functional approach, this study explored the relationship between physical activity intensity and adiposity, finding that reallocating time to higher intensity physical activity was associated with larger and more progressive decreases in adiposity.
STATISTICAL METHODS IN MEDICAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Charlotte Lund Rasmussen, Ales Gaba, Tyman Stanford, Jan Dygryn, Dorothea Dumuid, David Janda, Karel Hron
Summary: This study estimates the optimal durations of sleep, sedentary behavior, light physical activity, and moderate-to-vigorous physical activity associated with excess adiposity in children and adolescents. It suggests that optimizing the time spent on these behaviors is important in preventing excess adiposity.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Orthopedics
J. Lostak, A. Gaba, J. Dygryn, L. Balaz, N. Stefelova, J. Gallo
Summary: The study aimed to describe and analyze age differences in 24-hour movement behavior patterns among adults and older adults with end-stage knee osteoarthritis referred for total knee arthroplasty (TKA). The findings indicated that both adult and older adult groups maintained high levels of physical activity despite severe knee osteoarthritis, with adults showing a higher proportion of moderate-to-vigorous physical activity compared to older adults.
ACTA CHIRURGIAE ORTHOPAEDICAE ET TRAUMATOLOGIAE CECHOSLOVACA
(2022)
Article
Public, Environmental & Occupational Health
Lukas Rubin, Ales Gaba, Jana Pelclova, Nikola Stefelova, Lukas Jakubec, Jan Dygryn, Karel Hron
Summary: This study investigated the changes in sedentary behavior patterns and their associations with adiposity from childhood to adolescence. The results showed that the increase in sedentary behavior during this period was associated with an increase in fat mass percentage. Substituting sedentary time with high-intensity physical activity can reduce the risk of excess adiposity.
ARCHIVES OF PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Antonio Henrique Germano-Soares, Rafael M. Tassitano, Breno Quintela Farah, Aluisio Andrade-Lima, Marilia de Almeida Correia, Ales Gaba, Nikola Stefelova, Pedro Puech-Leao, Nelson Wolosker, Gabriel Grizzo Cucato, Raphael Mendes Ritti-Dias
Summary: The study revealed a positive association between moderate to vigorous-intensity physical activity (MVPA) and walking capacity in patients with symptomatic peripheral artery disease, while sedentary behavior and light-intensity physical activity were not associated. Reallocation of time from sedentary behavior to MVPA was found to be beneficial in improving walking capacity for both men and women.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2021)
