Synaptic basis of social dysfunction: a focus on postsynaptic proteins linking group-I mGluRs with AMPARs and NMDARs

Molecular and clinical characterization of 25 individuals with exonic deletions ofNRXN1and comprehensive review of the literature

(2013) Frédérique Béna et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Behavioural methods used in rodent models of autism spectrum disorders: Current standards and new developments

(2013) Markus Wöhr et al.   BEHAVIOURAL BRAIN RESEARCH

Mouse vocal communication system: Are ultrasounds learned or innate?

(2013) Gustavo Arriaga et al.   BRAIN AND LANGUAGE

The emerging role ofSHANKgenes in neuropsychiatric disorders

(2013) Audrey Guilmatre et al.   Developmental Neurobiology

Homer1 Mediates Acute Stress-Induced Cognitive Deficits in the Dorsal Hippocampus

(2013) K. V. Wagner et al.   JOURNAL OF NEUROSCIENCE

New technologies for examining the role of neuronal ensembles in drug addiction and fear

(2013) Fabio C. Cruz et al.   NATURE REVIEWS NEUROSCIENCE

Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling

(2013) Csaba Földy et al.   NEURON

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Altered Social Behaviours in Neurexin 1α Knockout Mice Resemble Core Symptoms in Neurodevelopmental Disorders

(2013) Hannah Mary Grayton et al.   PLoS One

Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism

(2013) K. Takeuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurexins

(2013) Carsten Reissner et al.   GENOME BIOLOGY

Developmental delays and reduced pup ultrasonic vocalizations but normal sociability in mice lacking the postsynaptic cell adhesion protein neuroligin2

(2012) Markus Wöhr et al.   BEHAVIOURAL BRAIN RESEARCH

Cellular and synaptic network defects in autism

(2012) João Peça et al.   CURRENT OPINION IN NEUROBIOLOGY

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4

(2012) E. Ey et al.   GENES BRAIN AND BEHAVIOR

Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics

(2012) Claudia Bagni et al.   JOURNAL OF CLINICAL INVESTIGATION

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Computerized video analysis of social interactions in mice

(2012) Fabrice de Chaumont et al.   NATURE METHODS

GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling

(2012) Seung Min Shin et al.   NATURE NEUROSCIENCE

Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex

(2012) R. Michelle Reith et al.   NEUROBIOLOGY OF DISEASE

High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism

(2012) Raymond J. Kelleher III et al.   PLoS One

Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism

(2012) S. J. Baudouin et al.   SCIENCE

Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

(2012) Claire S. Leblond et al.   PLoS Genetics

Interaction between genetic variants of DLGAP3 and SLC1A1 Affecting the Risk of Atypical Antipsychotics-Induced Obsessive-Compulsive Symptoms

(2011) Seunghyong Ryu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome

(2011) Alexia M. Thomas et al.   BEHAVIOURAL BRAIN RESEARCH

An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus

(2011) Mark R Etherton et al.   EMBO JOURNAL

Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology

(2011) Simone Berkel et al.   HUMAN MOLECULAR GENETICS

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes

(2011) Isabel Rodríguez-Escudero et al.   HUMAN MOLECULAR GENETICS

Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses

(2011) Chiara Verpelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Tsc1 In Vivo Impairs Hippocampal mGluR-LTD and Increases Excitatory Synaptic Function

(2011) H. S. Bateup et al.   JOURNAL OF NEUROSCIENCE

Sapap3 Deletion Anomalously Activates Short-Term Endocannabinoid-Mediated Synaptic Plasticity

(2011) M. Chen et al.   JOURNAL OF NEUROSCIENCE

Sapap3 Deletion Causes mGluR5-Dependent Silencing of AMPAR Synapses

(2011) Y. Wan et al.   JOURNAL OF NEUROSCIENCE

Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration

(2011) Margaret Sperow et al.   JOURNAL OF PHYSIOLOGY-LONDON

SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism

(2011) C M Durand et al.   MOLECULAR PSYCHIATRY

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area

(2011) Manuel Mameli et al.   NATURE NEUROSCIENCE

In utero exposure to cocaine delays postnatal synaptic maturation of glutamatergic transmission in the VTA

(2011) Camilla Bellone et al.   NATURE NEUROSCIENCE

Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c

(2011) Hilary Gerstein et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

mGluR5 and NMDA Receptors Drive the Experience- and Activity-Dependent NMDA Receptor NR2B to NR2A Subunit Switch

(2011) Jose A. Matta et al.   NEURON

The role of neurexins in schizophrenia and autistic spectrum disorder

(2011) A.C. Reichelt et al.   NEUROPHARMACOLOGY

Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior

(2011) Markus Wöhr et al.   PLoS One

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina

(2011) M. Hoon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

(2011) M. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

Family-based genetic association study of DLGAP3 in Tourette Syndrome

(2010) Jacquelyn Crane et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Association of MouseDlg4(PSD-95) Gene Deletion and HumanDLG4Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams' Syndrome

(2010) Michael Feyder et al.   AMERICAN JOURNAL OF PSYCHIATRY

Sociability and motor functions in Shank1 mutant mice

(2010) Jill L. Silverman et al.   BRAIN RESEARCH

Increased Dentate Gyrus Excitability in Neuroligin-2-Deficient Mice in Vivo

(2010) P. Jedlicka et al.   CEREBRAL CORTEX

Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population

(2010) Leigh Boardman et al.   COMPREHENSIVE PSYCHIATRY

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

(2010) Simone Berkel et al.   NATURE GENETICS

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

Degradation of Postsynaptic Scaffold GKAP and Regulation of Dendritic Spine Morphology by the TRIM3 Ubiquitin Ligase in Rat Hippocampal Neurons

(2010) Albert Y. Hung et al.   PLoS One

Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors

(2010) S.-Y. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered neuroligin expression is involved in social deficits in a mouse model of the fragile X syndrome

(2009) Regina Dahlhaus et al.   BEHAVIOURAL BRAIN RESEARCH

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Copy number changes of the microcephalin 1 gene (MCPH1) in patients with autism spectrum disorders

(2009) HM Ozgen et al.   CLINICAL GENETICS

Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit

(2009) K. Radyushkin et al.   GENES BRAIN AND BEHAVIOR

Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1

(2009) Jing Zhou et al.   HUMAN MOLECULAR GENETICS

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sapap3and pathological grooming in humans: Results from the OCD collaborative genetics study

(2008) O.J. Bienvenu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice

(2008) Kathryn K. Chadman et al.   Autism Research

The Autistic Neuron: Troubled Translation?

(2008) Raymond J. Kelleher et al.   CELL

Mechanisms of synaptic depression triggered by metabotropic glutamate receptors

(2008) C. Bellone et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2

(2008) J. Blundell et al.   GENES BRAIN AND BEHAVIOR

Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

(2008) A. Y. Hung et al.   JOURNAL OF NEUROSCIENCE

Multiple rare SAPAP3 missense variants in trichotillomania and OCD

(2008) S Züchner et al.   MOLECULAR PSYCHIATRY

Ultrasonic vocalizations: A tool for behavioural phenotyping of mouse models of neurodevelopmental disorders

(2008) Maria Luisa Scattoni et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

PTEN signaling in brain: neuropathology and tumorigenesis

(2008) R Endersby et al.   ONCOGENE

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals

(2008) Juhyun Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities

(2007) M.M. Fraser et al.   NEUROSCIENCE