Journal
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
Volume 114, Issue 4, Pages 461-468Publisher
WILEY-BLACKWELL
DOI: 10.1002/ejlt.201100019
Keywords
Antioxidant status; Cold-pressed flaxseed oil; High fat diet; Lipid profile; Vitamin E-enriched flaxseed oil
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Funding
- National 863 plan [2010AA023003]
- National Natural Science Foundation of China [31000777]
- Youth Chenguang Project of Science and Technology of Wuhan City of China [201150431068]
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In this study we evaluate whether cold-pressed flaxseed oil (CFO), vitamin E-enriched hot pressed and totally refined flaxseed oils (HRFOs) characterized by different qualities of micronutrients have beneficial effects on lipid profile and antioxidant status in high-fat fed rats. Male Wistar rats were fed synthetic diets containing 10% of HRFO, CFO, low-dose (100?mg/100?g oil) vitamin E-enriched HRFO (L-HRFO) or high-dose (200?mg/100?g oil) vitamin E-enriched HRFO (H-HRFO), respectively for 4 wk. The results showed that plasma triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol levels in CFO group decreased by 12, 21, and 18% compared with HRFO group (p?
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