Article
Nutrition & Dietetics
Drajat Martianto, Atikah Bararah, Nuri Andarwulan, Dominika srednicka-Tober
Summary: This study investigated plant sterols intake and food sources in Bogor, Indonesia, revealing an average intake of 229.76 mg/day mainly from cereals, vegetables, and fruit products. A list of potential plant sterol-enriched food items was developed for future functional food development in Indonesia. Further research is needed to confirm the efficacy and safety of introducing such products into habitual diets.
Article
Cardiac & Cardiovascular Systems
Birgit-Christiane Zyriax, Katrin Borof, Sascha Walter, Matthias Augustin, Eberhard Windler
Summary: The majority of participants are aware of the potential to lower cholesterol through lifestyle changes, but their knowledge of specific measures to lower plasma cholesterol may not align with current scientific evidence. There is a trend towards the use of phytosterol-enriched products by individuals at increased cardiovascular risk, independent of income levels.
Review
Nutrition & Dietetics
Christiana Oluwatoyin Ajanaku, Olabisi Theresa Ademosun, Prudence Osahenomanse Atohengbe, Samuel Oluwakayode Ajayi, Yemisi Dorcas Obafemi, Olayinka Ayotunde Owolabi, Paul Akinniyi Akinduti, Kolawole Oluseyi Ajanaku
Summary: Nutrition plays a crucial role in promoting individual health and has led to a global shift from pharmaceuticals to nutraceuticals due to the high cost and side effects associated with pharmaceutical consumption. This report reviews the bioactive compounds in ginger, turmeric, and garlic as potential natural therapeutics for cancer and heart-related diseases, discussing their analytical profiles, functional activities, and possible recommendations for disease treatment using these nutraceuticals.
FRONTIERS IN NUTRITION
(2022)
Review
Genetics & Heredity
Spurthi N. Nayak, B. Aravind, Sachin S. Malavalli, B. S. Sukanth, R. Poornima, Pushpa Bharati, Kathleen Hefferon, Chittaranjan Kole, Naveen Puppala
Summary: Functional foods, derived from plants, offer health benefits beyond basic nutrition, and advances in omics technologies can enhance the functional components of foods, improving crops and traditional medicines to address malnutrition and hunger more effectively.
FRONTIERS IN GENETICS
(2021)
Review
Nutrition & Dietetics
Maristella Donato, Elisabetta Faggin, Francesco Cinetto, Carla Felice, Maria Giovanna Lupo, Nicola Ferri, Marcello Rattazzi
Summary: Cardiovascular calcification refers to the deposition of calcium-phosphate crystals in arteries and heart valves, which increases the risk of cardiovascular diseases. Nutraceuticals like magnesium, zinc, iron, vitamin K, and phytate have shown potential in preventing vascular calcification, especially in high-risk populations. Further research is needed to determine the optimal dosage and efficacy of these nutraceuticals in preventing cardiovascular calcification.
Review
Food Science & Technology
Musthafa Mohamed Essa, Muhammed Bishir, Abid Bhat, Saravana Babu Chidambaram, Buthaina Al-Balushi, Hamdan Hamdan, Nagamaniammai Govindarajan, Robert P. Freidland, M. Walid Qoronfleh
Summary: Functional foods play a crucial role in maintaining a healthy lifestyle and reducing the risk of diseases. These foods contain functional ingredients that have potential health benefits. The market for functional foods is expanding and more research is needed to determine their potential health benefits.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Food Science & Technology
Franks Kamgang Nzekoue, Alessandro Alesi, Sauro Vittori, Gianni Sagratini, Giovanni Caprioli
Summary: This study evaluated the stability of phytosterols in whey cheese during processing and storage, developing an innovative analytical method for sterol determination. The results showed good heat-stability of phytosterols in the cheese matrix and maintained bioactivity during shelf-life.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Horticulture
Andrzej Kalisz, Zofia Wlodarczyk, Monika Bieniasz, Sylwester Smolen, Jarmila Neugebauerova, Bozena Szewczyk-Taranek, Bozena Pawlowska
Summary: The aim of this study was to investigate the profile of bioactive compounds in petals of 23 cultivars of garden roses. Flowers, especially those with red petals, were found to be a rich source of phenols, flavonoids, and anthocyanins. The chlorogenic acid content was not influenced by flower color, while white cultivars and those with pale colors had the highest level of hydroxychloroquine. Petals of all cultivars exhibited high levels of vitamin C and low levels of vitamins B. Glutathione was found in high levels in most examined roses. The presence of hydroxychloroquine in plant material was detected for the first time. Soluble oxalates content was very low. The high levels of phytochemicals in rose flowers make them excellent candidates for the food and nutraceutical industry. Some cultivars, such as 'Chorus', 'Abraham Darby', 'Graham Thomas', 'Mary Rose', 'Morning Jewel', 'Moje Hammarberg', are particularly rich sources of valuable bioactive ingredients such as phenols, flavonoids, anthocyanins, and vitamin C.
SCIENTIA HORTICULTURAE
(2023)
Review
Food Science & Technology
Mohamed A. Farag, Mohamed Sheashea, Chao Zhao, Amal A. Maamoun
Summary: UV-Vis spectroscopy plays a crucial role in quality control of food and dietary supplements, as well as in various other applications. With the aid of chemometric tools, it can effectively handle large UV-Vis datasets to provide spectral information on complex conjugated systems.
Review
Physiology
Deepu Pandita, Anu Pandita
Summary: The influence of nutrition and environment on human health is significant. Phytonutrients and pro-health nutrients can prevent various diseases. Plant-derived compounds play a vital role in human diet, affecting gene expression and signaling pathways, as well as epigenetics. The advancement in omics approaches has contributed to the understanding of functional food.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Nutrition & Dietetics
Yasuyo Urasaki, Thuc T. Le
Summary: This study explores the functional complementation of nine anti-adipogenic phytonutrients in obesity prevention and management. The phytonutrients were found to suppress fatty acid biosynthesis, activate glycolysis, and preserve cell-cell adhesion. In human cells and a murine model, the combination of these phytonutrients showed stronger anti-adipogenic effects, improving glucose tolerance and reducing obesity-related pathologies.
Article
Biochemistry & Molecular Biology
S. Baumgartner, D. Luetjohann, C. Husche, A. Kerksiek, A. K. Groen, R. P. Mensink, J. Plat
Summary: In this study, we evaluated the concentrations of oxyphytosterol (OPS) in plasma and various tissues of two genetically modified mouse models. The findings showed that while the levels of plant sterols (PS) were significantly elevated in the plasma of the dKO mice, the concentrations of OPS were comparable or even lower. This suggests that OPS are primarily formed in the liver and their presence in plasma is due to spill-over from the liver.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2022)
Review
Food Science & Technology
Ivonne Lozano Munoz, Nelson F. Diaz
Summary: Adequate daily intake of minerals is crucial for preventing chronic diseases, and seaweeds are rich in minerals and have high nutritional value. The review aims to compare mineral contents in different edible seaweeds and determine their safety in foods and contribution to dietary intake.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Medicine, General & Internal
Valeria Sutti Nunes, Angela de Oliveira Godoy Ilha, Guilherme da Silva Ferreira, Renata de Paula Assis Bombo, Milessa Silva Afonso, Maria Silvia Ferrari Lavrador, Roberta Marcondes Machado, Edna Regina Nakandakare, Eder Carlos Rocha Quinta, Ana Maria Lottenberg
Summary: This study investigated the relationship between plasma phytosterols and the body's cholesterol synthesis rate. The results showed that the lathosterol-to-cholesterol plasma ratio can predict the plasma cholesterol response to phytosterol feeding.
Review
Food Science & Technology
Jing-Wen Yang, Hong-Fang Ji
Summary: Phytosterols are bioactive food components found in plant cell membranes, especially in nuts and oilseeds. Many studies have shown their therapeutic potential for nonalcoholic fatty liver disease (NAFLD). They lower total cholesterol and triglyceride levels through various mechanisms and improve NAFLD.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Samar Y. Ahmad, James K. Friel, Dylan S. MacKay
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2020)
Review
Nutrition & Dietetics
Samar Y. Ahmad, James K. Friel, Dylan S. Mackay
Article
Medicine, Research & Experimental
Maryam Samsamikor, Dylan Mackay, Rebecca C. Mollard, Rotimi E. Aluko
Article
Medicine, Research & Experimental
Maryam Shamloo, Matthew J. Granger, Elke A. Trautwein, James D. House, Dylan MacKay
Article
Endocrinology & Metabolism
Peter A. Senior, Robyn L. Houlden, James Kim, Dylan Mackay, Seema Nagpal, Doreen Rabi, Diana Sherifali, Harpreet S. Bajaj
CANADIAN JOURNAL OF DIABETES
(2020)
Article
Nutrition & Dietetics
Rebecca C. Mollard, Alie Johnston, Alejandra Serrano Leon, Haizhou Wang, Peter J. Jones, Dylan S. MacKay
Summary: The study found that hemp protein, like soybean protein, dose-dependently lowers postprandial blood glucose and insulin concentrations compared to a carbohydrate control. There were no significant differences between the effects of hemp protein and soy protein.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2021)
Article
Nutrition & Dietetics
Alie J. Johnston, Rebecca C. Mollard, Dianna Dandeneau, Dylan S. MacKay, Nancy Ames, Julianne Curran, Danielle R. Bouchard, Peter J. Jones
Summary: Research shows that incorporating 40% pulse flour into extruded corn snacks can lead to lower pre-meal blood glucose and insulin responses for pinto bean and chickpea snacks. The findings suggest that the effects on blood glucose and insulin levels when replacing corn with pulse flours in extruded snacks are dependent on the type of pulse used.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2021)
Article
Endocrinology & Metabolism
Nika Klaprat, Chantal Benjamin, Joel Brandt, Natasha Gregoire, Kennedy Merrill, Dylan Mackay, Jane Yardley, Jonathan McGavock
CANADIAN JOURNAL OF DIABETES
(2020)
Article
Nutrition & Dietetics
Alie J. Johnston, Rebecca C. Mollard, Dianna Dandeneau, Dylan S. MacKay, Nancy Ames, Julianne Curran, Danielle R. Bouchard, Peter J. Jones
Summary: The study found that incorporating yellow pea protein and fiber in oat-based breakfast cereal can reduce postprandial glycemia. Different combinations of pulse fractions have varied effects on blood sugar and insulin concentrations.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2021)
Review
Medicine, General & Internal
Katrina Cachero, Matthew Granger, Rebecca C. Mollard, Nicole Askin, George N. Okoli, Ahmed M. Abou-Setta, Dylan MacKay
Summary: Obesity has become a major driver in the burden of chronic diseases, and clinically managed weight loss programs may offer a safer solution for those struggling with obesity or overweight.
SYSTEMATIC REVIEWS
(2021)
Article
Nutrition & Dietetics
Matthew J. Granger, Peter K. Eck, Itzel Vazquez-Vidal, Maryam Shamloo, James D. House, Dylan S. Mackay
Summary: The GenePredict Plant Sterol study aimed to validate the associations of LDL cholesterol lowering with specific APOE and CYP7A1 genosets through a priori recruitment, but the recruitment target could not be reached. Despite the shortfall, reductions in LDL cholesterol were similar across all genosets, indicating that the trial's objective may still have been met. In conclusion, APOE and CYP7A1 genotypes did not influence the effectiveness of LDL cholesterol reductions through dietary intervention with plant sterols, and it is challenging to obtain adequate numbers of participants in trials using genoset-based recruitment.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Endocrinology & Metabolism
Alice Y. Y. Cheng, Denice S. Feig, Josephine Ho, Rick Siemens, Harpreet Bajaj, Jeremy Gilbert, Robyn Houlden, James Kim, Dylan Mackay, Doreen M. Rabi, Peter Senior, Diana Sherifali
CANADIAN JOURNAL OF DIABETES
(2021)
Article
Medicine, Research & Experimental
Maryam Shamloo, Rebecca Mollard, Haizhou Wang, Kulwant Kingra, Navdeep Tangri, Dylan MacKay
Summary: The study aims to investigate the effects of resistant potato starch as a prebiotic in individuals with chronic kidney disease before the onset of dialysis, with changes in blood uremic toxins as the primary outcome. Secondary outcomes include the impact on symptoms, quality of life, and the abundance, diversity, and functionality of the gut microbiome.
Review
Urology & Nephrology
Kulwant Kingra, Sarah Curtis, Rebecca C. Mollard, Maryam Shamloo, Nicole Askin, Navdeep Tangri, Dylan MacKay
Summary: Limited and inconsistent evidence exists on the impact of resistant starch (RS) in adult patients with chronic kidney disease (CKD). Further research is needed to determine the safety and efficacy of RS supplementation in this population.
CANADIAN JOURNAL OF KIDNEY HEALTH AND DISEASE
(2022)
Article
Nutrition & Dietetics
Samar Y. Ahmad, James Friel, Dylan Mackay