An animated landscape representation of CD4+T-cell differentiation, variability, and plasticity: Insights into the behavior of populations versus cells

SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, Part 2: Biological evaluation

(2014) Tim R. Mosmann et al.   CYTOMETRY PART A

SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, Part 1: Algorithm design

(2014) Iftekhar Naim et al.   CYTOMETRY PART A

Phenotype Switching by Inflammation-Inducing Polarized Th17 Cells, but Not by Th1 Cells

(2014) G. Shi et al.   JOURNAL OF IMMUNOLOGY

Effector CD8 T Cell Development: A Balancing Act between Memory Cell Potential and Terminal Differentiation

(2014) N. S. Joshi et al.   JOURNAL OF IMMUNOLOGY

Celebrating Diversity in Memory T Cells

(2014) S. M. Kaech   JOURNAL OF IMMUNOLOGY

Geometrically Controlled Asymmetric Division of CD4+ T Cells Studied by Immunological Synapse Arrays

(2014) Hong-Ryul Jung et al.   PLoS One

Cytokine Diversity in the Th1-Dominated Human Anti-Influenza Response Caused by Variable Cytokine Expression by Th1 Cells, and a Minor Population of Uncommitted IL-2+IFNγ- Thpp Cells

(2014) Nan Deng et al.   PLoS One

Essentials of Th17 cell commitment and plasticity

(2013) P. Muranski et al.   BLOOD

Of Origins and Pedigrees: Lineage Tracing of Dendritic Cells

(2013) Carmen Gerlach et al.   CELL

Feedback Control of Gene Expression Variability in the Caenorhabditis elegans Wnt Pathway

(2013) Ni Ji et al.   CELL

Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection

(2013) Noah J. Tubo et al.   CELL

T helper cells plasticity in inflammation

(2013) Lorenzo Cosmi et al.   CYTOMETRY PART A

The who's who of T-cell differentiation: Human memory T-cell subsets

(2013) Yolanda D. Mahnke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A complex issue on CD4+T-cell subsets

(2013) Shuiping Jiang et al.   IMMUNOLOGICAL REVIEWS

Helper T-cell identity and evolution of differential transcriptomes and epigenomes

(2013) Golnaz Vahedi et al.   IMMUNOLOGICAL REVIEWS

Early signaling events that underlie fate decisions of naive CD4+T cells toward distinct T-helper cell subsets

(2013) Hidehiro Yamane et al.   IMMUNOLOGICAL REVIEWS

Dynamic regulatory network controlling TH17 cell differentiation

(2013) Nir Yosef et al.   NATURE

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

The CD4-centered universe of human T cell subsets

(2013) J. Geginat et al.   SEMINARS IN IMMUNOLOGY

The many faces of CD4 T cells: Roles in immunity and disease

(2013) Federica Sallusto et al.   SEMINARS IN IMMUNOLOGY

The plasticity of human Treg and Th17 cells and its role in autoimmunity

(2013) Markus Kleinewietfeld et al.   SEMINARS IN IMMUNOLOGY

T follicular helper cell diversity and plasticity

(2013) Jennifer L. Cannons et al.   TRENDS IN IMMUNOLOGY

Stochastic Cytokine Expression Induces Mixed T Helper Cell States

(2013) Miaoqing Fang et al.   PLOS BIOLOGY

Mapping Differentiation under Mixed Culture Conditions Reveals a Tunable Continuum of T Cell Fates

(2013) Yaron E. Antebi et al.   PLOS BIOLOGY

Stable T-bet+GATA-3+ Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopathologic Inflammation

(2013) Michael Peine et al.   PLOS BIOLOGY

Wnt-Notch signalling: An integrated mechanism regulating transitions between cell states

(2012) Silvia Muñoz-Descalzo et al.   BIOESSAYS

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

(2012) Jose M. Polo et al.   CELL

Helper T cell diversity and plasticity

(2012) Shingo Nakayamada et al.   CURRENT OPINION IN IMMUNOLOGY

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells

(2012) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses

(2012) Jinfang Zhu et al.   IMMUNITY

Quasi-potential landscape in complex multi-stable systems

(2012) J. X. Zhou et al.   Journal of the Royal Society Interface

The Acute Environment, Rather than T Cell Subset Pre-Commitment, Regulates Expression of the Human T Cell Cytokine Amphiregulin

(2012) Yilin Qi et al.   PLoS One

Activation-Induced B Cell Fates Are Selected by Intracellular Stochastic Competition

(2012) K. R. Duffy et al.   SCIENCE

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post-Darwinian biology?

(2011) Sui Huang   BIOESSAYS

Functional and Epigenetic Studies Reveal Multistep Differentiation and Plasticity of In Vitro-Generated and In Vivo-Derived Follicular T Helper Cells

(2011) Kristina T. Lu et al.   IMMUNITY

Rapid In Vivo Conversion of Effector T Cells into Th2 Cells during Helminth Infection

(2011) M. Panzer et al.   JOURNAL OF IMMUNOLOGY

Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding

(2011) Rong Lu et al.   NATURE BIOTECHNOLOGY

Regional and mucosal memory T cells

(2011) Brian S Sheridan et al.   NATURE IMMUNOLOGY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration

(2011) Chris Jopling et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways

(2011) S. Huang   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC

(2010) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions

(2010) Ahmed N. Hegazy et al.   IMMUNITY

A novel subset of CD4+TH2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma

(2010) Yui-Hsi Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms

(2010) J. Oliaro et al.   JOURNAL OF IMMUNOLOGY

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

(2010) Luca Mariani et al.   Molecular Systems Biology

Variability in gene expression underlies incomplete penetrance

(2010) Arjun Raj et al.   NATURE

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Effector T cell plasticity: flexibility in the face of changing circumstances

(2010) Kenneth M Murphy et al.   NATURE IMMUNOLOGY

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript

(2010) Maurice A. Canham et al.   PLOS BIOLOGY

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

(2009) Gang Wei et al.   IMMUNITY

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

(2009) David Bending et al.   JOURNAL OF CLINICAL INVESTIGATION

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

(2009) Nicolas Fazilleau et al.   NATURE IMMUNOLOGY

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells

(2009) Shelley R. Hough et al.   PLoS One

CD40–CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

(2009) Giandomenica Iezzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor

(2008) Lorenzo Cosmi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

(2008) Marc Veldhoen et al.   NATURE IMMUNOLOGY

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY