A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T-cell immunity in vivo

Exploiting the Role of Endogenous Lymphoid-Resident Dendritic Cells in the Priming of NKT Cells and CD8+ T Cells to Dendritic Cell-Based Vaccines

(2011) Troels R. Petersen et al.   PLoS One

Development and Characterization of Synthetic Glucopyranosyl Lipid Adjuvant System as a Vaccine Adjuvant

(2011) Rhea N. Coler et al.   PLoS One

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

(2011) M. K. L. MacLeod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a ‘high-affinity’ FcγRIIa genotype

(2010) Martyn A French et al.   AIDS

Induction of tumor-specific acquired immunity against already established tumors by selective stimulation of innate DEC-205+ dendritic cells

(2010) Keiichi Moriya et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

New adjuvants for human vaccines

(2010) M Lamine Mbow et al.   CURRENT OPINION IN IMMUNOLOGY

The synthetic TLR2 agonist BPPcysMPEG leads to efficient cross-priming against co-administered and linked antigens

(2010) Chittappen K. Prajeeth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HPV vaccine: Cervarix

(2010) Anne Szarewski   EXPERT OPINION ON BIOLOGICAL THERAPY

A Synthetic Adjuvant to Enhance and Expand Immune Responses to Influenza Vaccines

(2010) Rhea N. Coler et al.   PLoS One

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells

(2010) G. Nchinda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis

(2010) S. Bertholet et al.   Science Translational Medicine

Adjuvants for cancer vaccines

(2010) Thomas W. Dubensky et al.   SEMINARS IN IMMUNOLOGY

Co-encapsulation of antigen and Toll-like receptor ligand in cationic liposomes affects the quality of the immune response in mice after intradermal vaccination

(2010) Suzanne M. Bal et al.   VACCINE

TLR-based immune adjuvants

(2010) Folkert Steinhagen et al.   VACCINE

Role of adjuvants in modeling the immune response

(2010) Darrick Carter et al.   Current Opinion in HIV and AIDS

Dendritic cells require a systemic type I interferon response to mature and induce CD4+Th1 immunity with poly IC as adjuvant

(2009) M. Paula Longhi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

(2009) A. M. Didierlaurent et al.   JOURNAL OF IMMUNOLOGY

CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help

(2009) Yusuke Nakanishi et al.   NATURE

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antibody to Langerin/CD207 localizes large numbers of CD8 + dendritic cells to the marginal zone of mouse spleen

(2009) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced humoral and Type 1 cellular immune responses with Fluzone® adjuvanted with a synthetic TLR4 agonist formulated in an emulsion

(2009) Susan L. Baldwin et al.   VACCINE

Dendritic Cells In Vivo: A Key Target for a New Vaccine Science

(2008) Ralph M. Steinman   IMMUNITY

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

(2008) Olivier Joffre et al.   IMMUNOLOGICAL REVIEWS

Vaccine adjuvant systems: Enhancing the efficacy of sub-unit protein antigens

(2008) Yvonne Perrie et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Molecular and cellular signatures of human vaccine adjuvants

(2008) F. Mosca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

(2008) C. Trumpfheller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines

(2008) Q. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY

Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization

(2008) Igor M. Belyakov et al.   VIROLOGY