Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Differentiated Human Alveolar Type II Cells Secrete Antiviral IL-29 (IFN- 1) in Response to Influenza A Infection

(2014) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo

(2010) M. W. Munks et al.   BLOOD

Immune mechanisms of protection: can adjuvants rise to the challenge?

(2010) Amy S McKee et al.   BMC BIOLOGY

New adjuvants for human vaccines

(2010) M Lamine Mbow et al.   CURRENT OPINION IN IMMUNOLOGY

Malaria Vaccine Design: Immunological Considerations

(2010) Michael F. Good et al.   IMMUNITY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Cytotoxic T Cells Are the Predominant Players Providing Cross-Protective Immunity Induced by  -Irradiated Influenza A Viruses

(2010) Y. Furuya et al.   JOURNAL OF VIROLOGY

Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity

(2009) A. S. McKee et al.   JOURNAL OF IMMUNOLOGY

Vaccinia Virus-Based Multivalent H5N1 Avian Influenza Vaccines Adjuvanted with IL-15 Confer Sterile Cross-Clade Protection in Mice

(2009) L. L. M. Poon et al.   JOURNAL OF IMMUNOLOGY

AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

(2009) A. M. Didierlaurent et al.   JOURNAL OF IMMUNOLOGY

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity

(2008) Luigi Franchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF VIROLOGY

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

CD8+ T cell efficacy in vaccination and disease

(2008) Victor Appay et al.   NATURE MEDICINE

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE