Article
Cardiac & Cardiovascular Systems
Pankaj Puar, Makoto Hibino, C. David Mazer, Andrew T. Yan, Arjun K. Pandey, Adrian Quan, Hwee Teoh, David A. Hess, Raj Verma, Kim A. Connelly, Subodh Verma
Summary: The study found that empagliflozin use for 6 months resulted in a significant reduction in left ventricular mass indexed to body surface area (LVMi) in patients with type 2 diabetes and coronary artery disease. Further analysis showed that patients with higher baseline LVMi experienced greater improvement with the use of the drug.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Satomi Imanari, Yasuhiro Tomita, Satoshi Kasagi, Fusae Kawana, Yuka Kimura, Sugao Ishiwata, Koji Narui, Takatoshi Kasai
Summary: The study found a modest correlation between AHI determined by the ASV device AutoSet CS (ASC) and that calculated by polysomnography (PSG) in patients with HF and SDB. However, the ASC device tended to overestimate AHI and showed moderate agreement with PSG results.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Matthew Kodsi, David Makarious, Gary C. H. Gan, Preeti Choudhary, Liza Thomas
Summary: Recent advancements in heart failure therapies, combined with non-invasive cardiac imaging techniques, have led to improved clinical and structural outcomes. Reverse remodelling, as a biomarker for treatment success, has been correlated with patients' clinical response. The introduction of new therapeutic agents and the evaluation of cardiac reverse remodelling using non-invasive methods have expanded the possibilities for successful treatment.
Article
Medicine, General & Internal
Valentina Mantegazza, Valentina Volpato, Massimo Mapelli, Valentina Sassi, Elisabetta Salvioni, Irene Mattavelli, Gloria Tamborini, Piergiuseppe Agostoni, Mauro Pepi
Summary: This study evaluated the effects of S/V on HFrEF patients using 3D transthoracic echocardiography and found improvements in LV size and biventricular function in non-ischaemic patients, whereas only LV function improved in ischaemic patients, with no effect on RV function. Diastolic function and NT-proBNP significantly improved in both groups. The study highlights the different impacts of S/V on LV function between non-ischaemic and ischaemic patients.
Article
Clinical Neurology
Mahssa Karimi, Jan Hedner, Ludger Grote
Summary: Adaptive Servo Ventilation (ASV) treatment improves sleep quality, neurocognition, and daytime performance in patients with chronic heart failure (CHF) and Cheyne-Stokes respiration (CSR).
Article
Cardiac & Cardiovascular Systems
Mathias Baumert, Dominik Linz, Michael Pfeifer, Maria Tafelmeier, Philippe Felfeli, Michael Arzt, Sobhan S. Shahrbabaki
Summary: This study confirmed the effectiveness of adaptive servo-ventilation (ASV) in reducing hypoxaemic burden related to sleep apnoea in heart failure patients. However, a significant hypoxaemic burden remained, which was related to the severity of heart failure and may have negative implications for long-term cardiovascular outcomes.
Review
Cell Biology
Zhanhao Su, Yiwei Liu, Hao Zhang
Summary: Chronic hypoxia plays a crucial role in many cardiac diseases, affecting the heart's metabolic processes. However, the exact mechanisms of adaptive cardiac metabolism in response to chronic hypoxia are still not fully understood. New findings from animal and human studies are summarized to illustrate these mechanisms and potential treatment strategies in patients with chronic hypoxia.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Kaiming Wang, Erik Youngson, Jeffrey A. Bakal, Jissy Thomas, Finlay A. McAlister, Gavin Y. Oudit
Summary: This study followed 1089 patients over a period of time and found that patients with HFrecEF had better prognosis and quality of life. Echocardiographic markers of cardiac remodelling in HFrecEF patients showed gradual improvement, while changes in HFtrecEF patients were minimal and resembled those in patients with persistent HFrEF.
Article
Cardiac & Cardiovascular Systems
Guoqi Li, Yihui Shao, Hong-Chang Guo, Ying Zhi, Bokang Qiao, Ke Ma, Jie Du, Yong-Qiang Lai, Yulin Li
Summary: miR-27b-3p induces pathological cardiac remodelling and inhibition of endogenous miR-27b-3p or administration of FGF1 might suppress cardiac remodelling.
CARDIOVASCULAR RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Christoph Fisser, Lara Gall, Jannis Bureck, Victoria Vaas, Joerg Priefert, Sabine Fredersdorf, Florian Zeman, Dominik Linz, Holger Woehrle, Renaud Tamisier, Helmut Teschler, Martin R. R. Cowie, Michael Arzt
Summary: This study aimed to evaluate the effects of ASV on nocturnal ventricular arrhythmias in patients with CSA and HFrEF. The results showed that adding ASV to guideline-based medical management did not significantly affect nocturnal ventricular ectopy or tachyarrhythmia over a period of 12 months.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Jingting Wang, Naima Covassin, Tianxin Dai, Zhengyang Fan, Patiguli Yisilamu, Dance Sun, Fei Li, Jiang Xie
Summary: The effectiveness of ASV therapy in reducing cardiovascular and all-cause mortality in CSA patients remains debatable. However, ASV treatment can significantly reduce the risk of MACEs in patients with nadir nocturnal saturation <= 80%. For heart failure patients, those with LVEF > 33% or NYHA I/II classification benefit from ASV therapy in lowering MACEs risk compared to usual care.
Article
Cardiac & Cardiovascular Systems
Lingyu Xu, Joseph Pagano, Kelvin Chow, Gavin Y. Oudit, Mark J. Haykowsky, Yoko Mikami, Andrew G. Howarth, James A. White, Jonathan G. Howlett, Jason R. B. Dyck, Todd J. Anderson, Justin A. Ezekowitz, Richard B. Thompson, D. Ian Paterson
Summary: This study aimed to evaluate cardiac remodelling in patients with chronic heart failure, finding that changes in left ventricular mass index were predictive of long-term outcomes. Cardiac remodelling was common during serial CMR assessment of patients with chronic heart failure.
Article
Cardiac & Cardiovascular Systems
Lingyu Xu, Joseph Pagano, Kelvin Chow, Gavin Y. Oudit, Mark J. Haykowsky, Yoko Mikami, Andrew G. Howarth, James A. White, Jonathan G. Howlett, Jason R. B. Dyck, Todd J. Anderson, Justin A. Ezekowitz, Richard B. Thompson, D. Ian Paterson
Summary: This study evaluated cardiac remodelling in patients with chronic heart failure using cardiac magnetic resonance imaging. The change in left ventricular mass was identified as a predictor of long-term outcomes, while the change in left ventricular ejection fraction was not.
Article
Cardiac & Cardiovascular Systems
Salva R. Yurista, Herman H. W. Sillje, Kirsten T. Nijholt, Martin M. Dokter, Dirk J. van Veldhuisen, Rudolf A. de Boer, B. Daan Westenbrink
Summary: The study found that FXa inhibition with apixaban did not influence pathological cardiac remodelling after myocardial infarction. The apixaban-treated group showed similar outcomes in cardiac function, LV dilatation, LV hypertrophy, and interstitial fibrosis compared to the placebo group.
CARDIOVASCULAR DRUGS AND THERAPY
(2021)
Article
Cardiac & Cardiovascular Systems
Alberto Aimo, Iacopo Fabiani, Giuseppe Vergaro, Chiara Arzilli, Vladyslav Chubuchny, Emilio Maria Pasanisi, Christina Petersen, Elisa Poggianti, Claudia Taddei, Nicola Riccardo Pugliese, Antoni Bayes-Genis, Josep Lupon, Alberto Giannoni, Andrea Ripoli, Georgios Georgiopoulos, Claudio Passino, Michele Emdin
Summary: The study found that an increase in left ventricular ejection fraction of >10 U and an increase in LVEF >= 1 category are stronger predictors of cardiovascular death than LVESV reduction >= 15%.
Article
Public, Environmental & Occupational Health
Yuko Kachi, Takeo Fujiwara, Hisashi Eguchi, Akiomi Inoue, Sachiko Baba, Hiroshi Ohta, Akizumi Tsutsumi
Summary: The study found a link between maternity harassment and depression during pregnancy, with 24.8% of pregnant women experiencing maternity harassment. Even teleworking did not reduce the impact of maternity harassment on depression.
JOURNAL OF OCCUPATIONAL HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Yuko Kachi, Aya Abe, Hisashi Eguchi, Akiomi Inoue, Akizumi Tsutsumi
Summary: The study found a significant association between mothers' nonstandard work schedules and adolescent obesity in high-income families, but this association was no longer significant after adjusting for confounders. There was no clear association between mothers' nonstandard work schedules and adolescent obesity in low-income families. Policy makers should consider mothers' work schedules as a factor in preventing adolescent obesity.
Article
Health Care Sciences & Services
Natsu Sasaki, Kotaro Imamura, Thuy Thi Thu Tran, Huong Thanh Nguyen, Kazuto Kuribayashi, Asuka Sakuraya, Thu Minh Bui, Quynh Thuy Nguyen, Nga Thi Nguyen, Giang Thi Huong Nguyen, Melvyn Weibin Zhang, Harry Minas, Yuki Sekiya, Kazuhiro Watanabe, Akizumi Tsutsumi, Akihito Shimazu, Norito Kawakami
Summary: The study in Vietnam demonstrated that a smartphone-based stress management program could improve work engagement in nurses in the short term. However, the effect was small and temporary, requiring further improvements for greater and more sustained impact on work engagement.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Akiomi Inoue, Hisashi Eguchi, Yuko Kachi, Akizumi Tsutsumi
Summary: The level of adaptation to management philosophy is significantly associated with employees' decision to seek medical care.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Reiko Inoue, Hiroyuki Hikichi, Akiomi Inoue, Yuko Kachi, Hisashi Eguchi, Kazuhiro Watanabe, Yumi Arai, Noboru Iwata, Akizumi Tsutsumi
Summary: This study found that coworker support is associated with reduced psychological distress among employees, while supervisor support does not have a significant association with reduced distress.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Environmental Sciences
Natsu Sasaki, Akiomi Inoue, Hiroki Asaoka, Yuki Sekiya, Daisuke Nishi, Akizumi Tsutsumi, Kotaro Imamura
Summary: This study validated the Japanese version of O'Donovan et al.'s psychological safety scale and found associations between psychological safety and mental health and job-related outcomes. The findings highlight the importance of psychological safety for employees' mental health and performance.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Kanami Tsuno, Norito Kawakami, Akizumi Tsutsumi, Akihito Shimazu, Akiomi Inoue, Yuko Odagiri, Teruichi Shimomitsu
Summary: Bullying victims and witnesses in the workplace are significantly associated with physical and mental outcomes as well as organizational outcomes.
Review
Medicine, General & Internal
Natsu Sasaki, Kotaro Imamura, Kazuhiro Watanabe, Yui Hidaka, Emiko Ando, Hisashi Eguchi, Akiomi Inoue, Kanami Tsuno, Yu Komase, Mako Iida, Yasumasa Otsuka, Asuka Sakuraya, Yumi Asai, Mai Iwanaga, Yuka Kobayashi, Reiko Inoue, Akihito Shimazu, Akizumi Tsutsumi, Norito Kawakami
Summary: This study aims to conduct a systematic review and meta-analysis to examine the relationship between psychosocial factors at work and menstrual abnormalities and fertility in female workers. The study will include literature with longitudinal or prospective cohort designs and assess the quality of selected studies and meta-bias.
SYSTEMATIC REVIEWS
(2022)
Article
Obstetrics & Gynecology
Yuko Kachi, Takeo Fujiwara, Akiomi Inoue, Sachiko Baba, Hisashi Eguchi, Hiroshi Ohta, Akizumi Tsutsumi
Summary: This study investigated the effects of pregnancy discrimination on postpartum depressive symptoms and the mediation effects of prenatal depressive symptoms. The findings showed that pregnancy discrimination has adverse effects on postpartum depressive symptoms, partially mediated by prenatal depressive symptoms.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Health Care Sciences & Services
Kazuhiro Watanabe, Akizumi Tsutsumi
Summary: This study developed and evaluated a deep learning model optimized for predicting depression and anxiety in workers, achieving good classification accuracy and predictive results by monitoring and predicting workers' mental health using physical activity data and psychological distress indicators.
JMIR FORMATIVE RESEARCH
(2022)
Article
Health Care Sciences & Services
Kazuhiro Watanabe, Shoichi Okusa, Mitsuhiro Sato, Hideki Miura, Masahiro Morimoto, Akizumi Tsutsumi
Summary: The study aimed to investigate the effectiveness of the ASHARE app in improving physical activity and reducing depression and anxiety, as well as its implementation outcomes. The results showed that the app did not significantly improve physical activity or psychological distress, but there was a decrease in the number of participants with severe psychological distress. The scores for acceptability, appropriateness, and satisfaction of the app were lower compared to previous studies.
JMIR FORMATIVE RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Akiomi Inoue, Hisashi Eguchi, Yuko Kachi, Akizumi Tsutsumi
Summary: This study examines the associations between perceived psychosocial safety climate (PSC) and psychological distress as well as work engagement in Japanese employees. It also explores the mediation effects of job demands and job resources in these associations. The results indicate that perceived PSC is negatively related to psychological distress and positively related to work engagement, and these associations are partially mediated by job demands and job resources.
JOURNAL OF OCCUPATIONAL HEALTH
(2023)
Review
Public, Environmental & Occupational Health
Kyoko Nomura, Kyoko Kitagawa, Mayumi Tsuji, Miho Iida, Mizuki Aoki, Kasane Miyauchi, Junko Hirayama, Kengo Nagashima, Toru Takebayashi, Akizumi Tsutsumi
Summary: This study investigates the quantity and quality of scientific evidence regarding comprehensive health issues of working women in occupational health. A scoping review of original articles published in PubMed and Ichu-shi was conducted. Mental health was the most frequently studied area, followed by work-related and lifestyle-related diseases. The majority of studies employed descriptive or cross-sectional designs, highlighting the need for higher-quality research designs in this field.
JOURNAL OF OCCUPATIONAL HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Kazuhiro Watanabe, Akiomi Inoue, Hisashi Eguchi, Noboru Iwata, Yuko Odagiri, Akizumi Tsutsumi
Summary: This study suggests new organizational-level item pools that companies can utilize to accomplish management philosophy and mission statements and improve work environment based on the analysis of management messages on company websites.
JOURNAL OF OCCUPATIONAL HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Takashi Oshio, Akiomi Inoue, Akizumi Tsutsumi
Summary: The study found that role ambiguity and four job stressors are positively associated with psychological distress, with role ambiguity significantly amplifying the impact of job stressors. Reducing role ambiguity is crucial in mitigating the adverse effects of job stress on workers' psychological well-being.
JOURNAL OF OCCUPATIONAL HEALTH
(2021)
