Adaptive Cardiac Metabolism Under Chronic Hypoxia: Mechanism and Clinical Implications
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Adaptive Cardiac Metabolism Under Chronic Hypoxia: Mechanism and Clinical Implications
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-02-02
DOI
10.3389/fcell.2021.625524
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Efficacy and safety of trimetazidine after percutaneous coronary intervention (ATPCI): a randomised, double-blind, placebo-controlled trial
- (2020) Roberto Ferrari et al. LANCET
- Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019
- (2020) Gregory A. Roth et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases
- (2019) Dahye Lee et al. JOURNAL OF MEDICINAL CHEMISTRY
- Metabolic Risk Factors and Left Ventricular Diastolic Function in Middle‐Aged Chinese Living in the Tibetan Plateau
- (2019) Congyi Zheng et al. Journal of the American Heart Association
- Assessing the effect of hypoxia on cardiac metabolism using hyperpolarized 13 C magnetic resonance spectroscopy
- (2019) Lydia M. Le Page et al. NMR IN BIOMEDICINE
- Chronic hypoxia–induced Cirbp hypermethylation attenuates hypothermic cardioprotection via down-regulation of ubiquinone biosynthesis
- (2019) Yiwei Liu et al. Science Translational Medicine
- Unlocking the Secrets of Mitochondria in the Cardiovascular System
- (2019) Rong Tian et al. CIRCULATION
- Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications
- (2018) Andrew J. Murray et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia
- (2018) Alessandra Ferri et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
- (2018) Michal K. Handzlik et al. JOURNAL OF PHYSIOLOGY-LONDON
- The role of dichloroacetate in improving acute hypoxic tolerance and cardiac function: translation to failing hearts?
- (2018) Da Hye Kim et al. JOURNAL OF PHYSIOLOGY-LONDON
- Metabolic remodelling in heart failure
- (2018) Edoardo Bertero et al. Nature Reviews Cardiology
- Hypoxia-inducible factor 1 signalling, metabolism and its therapeutic potential in cardiovascular disease
- (2018) Maria da Luz Sousa Fialho et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mechanisms of cardiovascular disease in obstructive sleep apnoea
- (2018) Silke Ryan Journal of Thoracic Disease
- Comorbid obstructive sleep apnoea and chronic obstructive pulmonary disease and the risk of cardiovascular disease
- (2018) Walter T. McNicholas Journal of Thoracic Disease
- The effects of the ketone body β-hydroxybutyrate on isolated rat ventricular myocyte excitation-contraction coupling
- (2018) Matthew Klos et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Protein kinase C and cardiac dysfunction: a review
- (2017) Raphael M. Singh et al. HEART FAILURE REVIEWS
- The Roles of Hypoxia Signaling in the Pathogenesis of Cardiovascular Diseases
- (2017) Hajime Abe et al. Journal of Atherosclerosis and Thrombosis
- Metabolic basis to Sherpa altitude adaptation
- (2017) James A. Horscroft et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coenzyme Q10 and Heart Failure
- (2016) Abhinav Sharma et al. Circulation-Heart Failure
- CV Protection in the EMPA-REG OUTCOME Trial: A “Thrifty Substrate” Hypothesis
- (2016) Ele Ferrannini et al. DIABETES CARE
- Metabolic support for the heart: complementary therapy for heart failure?
- (2016) Ward A. Heggermont et al. EUROPEAN JOURNAL OF HEART FAILURE
- On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
- (2016) Mark A. Cole et al. FASEB JOURNAL
- Assessment of the Physiological Adaptations to Chronic Hypoxemia in Eisenmenger Syndrome
- (2016) S.E. Bowater et al. Congenital Heart Disease
- Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models
- (2015) Desiree Abdurrachim et al. CARDIOVASCULAR RESEARCH
- Trimetazidine protects cardiomyocytes against hypoxia-induced injury through ameliorates calcium homeostasis
- (2015) Jinhong Wei et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Glucose Homeostasis During Short-term and Prolonged Exposure to High Altitudes
- (2015) Orison O. Woolcott et al. ENDOCRINE REVIEWS
- Mitochondrial biogenesis and dynamics in the developing and diseased heart
- (2015) Gerald W. Dorn et al. GENES & DEVELOPMENT
- Estrogen-Related Receptor α (ERRα) is required for adaptive increases in PGC-1 isoform expression during electrically stimulated contraction of adult cardiomyocytes in sustained hypoxic conditions
- (2015) Kathryn F. Cunningham et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation
- (2015) Latt S. Mansor et al. JOURNAL OF PHYSIOLOGY-LONDON
- Altered Oxygen Utilisation in Rat Left Ventricle and Soleus after 14 Days, but Not 2 Days, of Environmental Hypoxia
- (2015) James A. Horscroft et al. PLoS One
- Thiazolidinediones and the Promise of Insulin Sensitization in Type 2 Diabetes
- (2014) Raymond E. Soccio et al. Cell Metabolism
- Human high-altitude adaptation: forward genetics meets the HIF pathway
- (2014) Abigail W. Bigham et al. GENES & DEVELOPMENT
- Malonyl CoA: A promising target for the treatment of cardiac disease
- (2014) Natasha Fillmore et al. IUBMB LIFE
- Prevalence of congenital heart disease at live birth: an accurate assessment by echocardiographic screening
- (2013) Qu-ming Zhao et al. ACTA PAEDIATRICA
- Roles of histone deacetylation and AMP kinase in regulation of cardiomyocyte PGC-1α gene expression in hypoxia
- (2013) Angela Ramjiawan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Hypoxia-Inducible Factor 1 and Cardiovascular Disease
- (2013) Gregg L. Semenza Annual Review of Physiology
- Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes
- (2013) Stephen C. Kolwicz et al. CIRCULATION RESEARCH
- Metabolic adaptation to chronic hypoxia in cardiac mitochondria
- (2012) Lisa C. Heather et al. BASIC RESEARCH IN CARDIOLOGY
- Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects
- (2012) Steen Larsen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Review: Quantifying Mitochondrial Dysfunction in Complex Diseases of Aging
- (2012) Martin P. Horan et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Metabolic insight into mechanisms of high-altitude adaptation in Tibetans
- (2012) Ri-Li Ge et al. MOLECULAR GENETICS AND METABOLISM
- Hypoxemia in patients with COPD: cause, effects, and disease progression
- (2012) Walter McNicholas et al. International Journal of Chronic Obstructive Pulmonary Disease
- Chronic hypoxia-induced alterations in mitochondrial energy metabolism are not reversible in rat heart ventricles
- (2010) Karine Nouette-Gaulain et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patients
- (2010) Lingyun Zhu et al. CELL RESEARCH
- Analysis of Metabolic Remodeling in Compensated Left Ventricular Hypertrophy and Heart Failure
- (2010) Takao Kato et al. Circulation-Heart Failure
- Trimetazidine: a meta-analysis of randomised controlled trials in heart failure
- (2010) D. Gao et al. HEART
- PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition
- (2010) Joy McCarthy et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1
- (2010) Nuria Pescador et al. PLoS One
- Improved Energy Supply Regulation in Chronic Hypoxic Mouse Counteracts Hypoxia-Induced Altered Cardiac Energetics
- (2010) Guillaume Calmettes et al. PLoS One
- The Randle cycle revisited: a new head for an old hat
- (2009) Louis Hue et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Pioglitazone Improves Cardiac Function and Alters Myocardial Substrate Metabolism Without Affecting Cardiac Triglyceride Accumulation and High-Energy Phosphate Metabolism in Patients With Well-Controlled Type 2 Diabetes Mellitus
- (2009) Rutger W. van der Meer et al. CIRCULATION
- Role of Pulse Oximetry in Examining Newborns for Congenital Heart Disease: A Scientific Statement from the AHA and AAP
- (2009) W. T. Mahle et al. PEDIATRICS
- Modular control analysis of effects of chronic hypoxia on mouse heart
- (2008) Guillaume Calmettes et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation