Mechanisms in endocrinology: Non-alcoholic fatty liver disease in common endocrine disorders

Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals

(2013) Howard C. Masuoka et al.   Annals of the New York Academy of Sciences

Increased Risk of Type 2 Diabetes in Subjects with Both Elevated Liver Enzymes and Ultrasonographically Diagnosed Nonalcoholic Fatty Liver Disease: A 4-year Longitudinal Study

(2013) Ji Hun Choi et al.   ARCHIVES OF MEDICAL RESEARCH

Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks?

(2013) S. J. Cleland et al.   DIABETOLOGIA

Glucocorticoids Fail to Cause Insulin Resistance in Human Subcutaneous Adipose Tissue In Vivo

(2013) Jonathan M. Hazlehurst et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Prognostic implication of liver histology in patients with nonalcoholic fatty liver disease in diabetes

(2013) Iliana Doycheva et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

Safety and efficacy of liraglutide in patients with type 2 diabetes and elevated liver enzymes: individual patient data meta-analysis of the LEAD program

(2012) M. J. Armstrong et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model

(2012) Hitoshi Nishizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A low level of serum total testosterone is independently associated with nonalcoholic fatty liver disease

(2012) Sunmi Kim et al.   BMC GASTROENTEROLOGY

Estrogen Treatment After Ovariectomy Protects Against Fatty Liver and May Improve Pathway-Selective Insulin Resistance

(2012) L. Zhu et al.   DIABETES

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

(2012) C. Flannery et al.   DIABETES

Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver [Review]

(2012) Yutaka Takahashi   ENDOCRINE JOURNAL

Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1

(2012) Gareth G. Lavery et al.   ENDOCRINOLOGY

Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy

(2012) H. Nishizawa et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Hepatic steatosis, GH deficiency and the effects of GH replacement: a Liverpool magnetic resonance spectroscopy study

(2012) Chris J Gardner et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Body compositional and cardiometabolic effects of testosterone therapy in obese men with severe obstructive sleep apnoea: a randomised placebo-controlled trial

(2012) Camilla M Hoyos et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

(2012) Naga Chalasani et al.   GASTROENTEROLOGY

Nonalcoholic steatohepatitis versus steatosis: Adipose tissue insulin resistance and dysfunctional response to fat ingestion predict liver injury and altered glucose and lipoprotein metabolism

(2012) Giovanni Musso et al.   HEPATOLOGY

The epidemiology, pathogenesis and histopathology of fatty liver disease

(2012) Adam P Levene et al.   HISTOPATHOLOGY

Visceral Adiposity Index Is Associated with Insulin Sensitivity and Adipocytokine Levels in Newly Diagnosed Acromegalic Patients

(2012) A. Ciresi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Polycystic Ovary Syndrome with Hyperandrogenism Is Characterized by an Increased Risk of Hepatic Steatosis Compared to Nonhyperandrogenic PCOS Phenotypes and Healthy Controls, Independent of Obesity and Insulin Resistance

(2012) Helen Jones et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fat Content in Liver and Skeletal Muscle Changes in a Reciprocal Manner in Patients with Acromegaly during Combination Therapy with a Somatostatin Analog and a GH Receptor Antagonist: A Randomized Clinical Trial

(2012) Michael Madsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

(2012) Rohit Anthony Sinha et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of subclinical hypothyroidism on the development of non-alcoholic fatty liver disease: A prospective case-control study

(2012) Lei Xu et al.   JOURNAL OF HEPATOLOGY

Non-alcoholic fatty liver disease across the spectrum of hypothyroidism

(2012) Goh Eun Chung et al.   JOURNAL OF HEPATOLOGY

Oestradiol is a protective factor for non-alcoholic fatty liver disease in healthy men

(2012) G-X. Tian et al.   Obesity Reviews

Exendin-4 Improves Steatohepatitis by Increasing Sirt1 Expression in High-Fat Diet-Induced Obese C57BL/6J Mice

(2012) Jinmi Lee et al.   PLoS One

A Switch in Hepatic Cortisol Metabolism across the Spectrum of Non Alcoholic Fatty Liver Disease

(2012) Adeeba Ahmed et al.   PLoS One

Association between Serum Growth Hormone Levels and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study

(2012) Lei Xu et al.   PLoS One

Improved Glycaemia Correlates with Liver Fat Reduction in Obese, Type 2 Diabetes, Patients Given Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists

(2012) Daniel J. Cuthbertson et al.   PLoS One

Carbenoxolone Treatment Ameliorated Metabolic Syndrome in WNIN/Ob Obese Rats, but Induced Severe Fat Loss and Glucose Intolerance in Lean Rats

(2012) Siva Sankara Vara Prasad Sakamuri et al.   PLoS One

Tetradian oscillation of estrogen receptor   is necessary to prevent liver lipid deposition

(2012) A. Villa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inverse Association Between Serum Free Thyroxine Levels and Hepatic Steatosis: Results from the Study of Health in Pomerania

(2012) Till Ittermann et al.   THYROID

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Visceral adiposity index is associated with significant fibrosis in patients with non-alcoholic fatty liver disease

(2011) S. Petta et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet

(2011) Jamie E. Mells et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Long-term metformin treatment is able to reduce the prevalence of metabolic syndrome and its hepatic involvement in young hyperinsulinaemic overweight patients with polycystic ovarian syndrome

(2011) Maria F. Gangale et al.   CLINICAL ENDOCRINOLOGY

Nonalcoholic fatty liver disease is associated with increased GHBP and reduced GH/IGF-I levels

(2011) Alessandra Fusco et al.   CLINICAL ENDOCRINOLOGY

Effects of an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, MK-0916, in patients with type 2 diabetes mellitus and metabolic syndrome

(2011) P. U. Feig et al.   DIABETES OBESITY & METABOLISM

Increased prevalence of chronic kidney disease in patients with Type 1 diabetes and non-alcoholic fatty liver

(2011) G. Targher et al.   DIABETIC MEDICINE

Prevalence of Hypothyroidism in Nonalcoholic Fatty Liver Disease

(2011) Mangesh R. Pagadala et al.   DIGESTIVE DISEASES AND SCIENCES

Thyroid Hormone Receptor-α Gene Knockout Mice Are Protected from Diet-Induced Hepatic Insulin Resistance

(2011) François R. Jornayvaz et al.   ENDOCRINOLOGY

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

(2011) M. E. Miquilena-Colina et al.   GUT

Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and toll-like receptor activation

(2011) Christian L. Roth et al.   HEPATOLOGY

Is nonalcoholic steatohepatitis associated with a high-though-normal thyroid stimulating hormone level and lower cholesterol levels?

(2011) Lucia Carulli et al.   Internal and Emergency Medicine

Nonalcoholic Fatty Liver Disease Is Associated with Low Circulating Levels of Insulin-Like Growth Factor-I

(2011) Franco Arturi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism

(2011) Guoping Li et al.   JOURNAL OF LIPID RESEARCH

Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients

(2011) Edith Koehler et al.   LIVER INTERNATIONAL

Ultrasonographic and laboratory markers of metabolic and cardiovascular disease risk in obese women with polycystic ovary syndrome

(2011) L. F. N. Zueff et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Exenatide in the Treatment of Diabetic Patients With Non-Alcoholic Steatohepatitis: A Case Series

(2010) Patrick R Kenny et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease

(2010) Christopher L. Gentile et al.   BIOFACTORS

Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study

(2010) Svetlana Y. Kalinchenko et al.   CLINICAL ENDOCRINOLOGY

The 11- -Hydroxysteroid Dehydrogenase Type 1 Inhibitor INCB13739 Improves Hyperglycemia in Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy

(2010) J. Rosenstock et al.   DIABETES CARE

Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes

(2010) Giovanni Targher et al.   JOURNAL OF HEPATOLOGY

Impact of artificial sunlight therapy on the progress of non-alcoholic fatty liver disease in rats

(2010) Toshiaki Nakano et al.   JOURNAL OF HEPATOLOGY

Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis

(2010) Stergios A. Polyzos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

BMI and Metabolic Profile in Patients With Prolactinoma Before and After Treatment With Dopamine Agonists

(2010) Cintia M. dos Santos Silva et al.   Obesity

Insulin sensitivity and lipid profile in prolactinoma patients before and after normalization of prolactin by dopamine agonist therapy

(2010) Katarina Berinder et al.   Pituitary

Effects of androgens on adipocyte differentiation and adipose tissue explant metabolism in men and women

(2009) Karine Blouin et al.   CLINICAL ENDOCRINOLOGY

Thyroid Hormone Effects on Whole-Body Energy Homeostasis and Tissue-Specific Fatty Acid Uptakein Vivo

(2009) Lars P. Klieverik et al.   ENDOCRINOLOGY

Improvement of the Metabolic Syndrome and of Non-alcoholic Liver Steatosis upon Treatment of Hypogonadal Elderly Men with Parenteral Testosterone Undecanoate

(2009) A. Haider et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Hepatic steatosis in young lean insulin resistant women with polycystic ovary syndrome

(2009) Athina Markou et al.   FERTILITY AND STERILITY

Endocrine factors associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome: Do androgens play a role?

(2009) Robert P. Kauffman et al.   GYNECOLOGICAL ENDOCRINOLOGY

Effects of estrogen and androgen deprivation on the progression of non-alcoholic steatohepatitis (NASH) in male Sprague-Dawley rats

(2009) Yanjun Mu et al.   HEPATOLOGY RESEARCH

Hepatic steatosis is associated with low serum testosterone and high serum DHEAS levels in men

(2009) Henry Völzke et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Pathogenesis of non-alcoholic fatty liver disease

(2009) J. K. Dowman et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

The Glucocorticoid Receptor Controls Hepatic Dyslipidemia through Hes1

(2008) Ulrike Lemke et al.   Cell Metabolism

Hepatic 11beta-HSD1 mRNA expression in fatty liver and nonalcoholic steatohepatitis

(2008) Sarah Konopelska et al.   CLINICAL ENDOCRINOLOGY

Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor

(2008) Hung-Yun Lin et al.   HEPATOLOGY

Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist

(2008) Edward E. Cable et al.   HEPATOLOGY

Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C

(2008) Satoru Yatsuji et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease

(2008) Janus P. Ong et al.   JOURNAL OF HEPATOLOGY

Mechanisms of Disease Progression in Nonalcoholic Fatty Liver Disease

(2008) Janice Jou et al.   SEMINARS IN LIVER DISEASE