Genetic variability of pain perception and treatment—clinical pharmacological implications

Nerve Growth Factor as a Signaling Molecule for Nerve Cells and also for the Neuroendocrine-Immune Systems

(2011) Marco Fiore et al.   REVIEWS IN THE NEUROSCIENCES

Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia

(2010) Jin-Sung Choi et al.   BRAIN

Multiple chronic pain states are associated with a common amino acid–changing allele in KCNS1

(2010) Michael Costigan et al.   BRAIN

A new Nav1.7 sodium channel mutation I234T in a child with severe pain

(2010) Hye-Sook Ahn et al.   EUROPEAN JOURNAL OF PAIN

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

A Novel Alternatively Spliced Isoform of the Mu-Opioid Receptor: Functional Antagonism

(2010) Pavel Gris et al.   Molecular Pain

A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome

(2010) Barbara Kremeyer et al.   NEURON

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

(2010) Nancy E. Lane et al.   NEW ENGLAND JOURNAL OF MEDICINE

A KCNJ6 (Kir3.2, GIRK2) gene polymorphism modulates opioid effects on analgesia and addiction but not on pupil size

(2010) Jörn Lötsch et al.   Pharmacogenetics and Genomics

A critical appraisal of human genotyping for pain therapy

(2010) Jörn Lötsch et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A sodium channel geneSCN9Apolymorphism that increases nociceptor excitability

(2009) Mark Estacion et al.   ANNALS OF NEUROLOGY

Cross-sectional Assessment of the Consequences of a GTP Cyclohydrolase 1 Haplotype for Specialized Tertiary Outpatient Pain Care

(2009) Alexandra Doehring et al.   CLINICAL JOURNAL OF PAIN

Targeting voltage-gated sodium channels for pain therapy

(2009) Jeffrey J Clare   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Fatal and severe codeine intoxication in 3-year-old twins—interpretation of drug and metabolite concentrations

(2009) Nerea Ferreirós et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Genetic Contributions to Clinical Pain and Analgesia: Avoiding Pitfalls in Genetic Research

(2009) Hyungsuk Kim et al.   JOURNAL OF PAIN

Two novel SCN9A mutations causing insensitivity to pain

(2009) K. B. Nilsen et al.   PAIN

Can extremely low or high morphine formation from codeine be predicted prior to therapy initiation?

(2009) Jörn Lötsch et al.   PAIN

Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment

(2009) Carmen Walter et al.   PAIN

Are we getting anywhere in human pain genetics?

(2009) Jeffrey S. Mogil   PAIN

A GTP cyclohydrolase 1 genetic variant delays cancer pain

(2009) Jörn Lötsch et al.   PAIN

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution

(2009) Alexandra Doehring et al.   Pharmacogenetics and Genomics

Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers

(2009) Jörn Lötsch et al.   Pharmacogenetics and Genomics

Genetic modulation of the pharmacological treatment of pain

(2009) Jörn Lötsch et al.   PHARMACOLOGY & THERAPEUTICS

Association between KCNJ6 (GIRK2) Gene Polymorphisms and Postoperative Analgesic Requirements after Major Abdominal Surgery

(2009) Daisuke Nishizawa et al.   PLoS One

Analgesic targets: today and tomorrow

(2009) Ian W. Rodger   INFLAMMOPHARMACOLOGY

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

(2008) Irmgard Tegeder et al.   EUROPEAN JOURNAL OF PAIN

Expansion of the human μ-opioid receptor gene architecture: novel functional variants

(2008) Svetlana A. Shabalina et al.   HUMAN MOLECULAR GENETICS

A Common Human μ-Opioid Receptor Genetic Variant Diminishes the Receptor Signaling Efficacy in Brain Regions Processing the Sensory Information of Pain

(2008) Bruno Georg Oertel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Does the Pain-Protective GTP Cyclohydrolase Haplotype Significantly Alter the Pattern or Severity of Pain in Humans with Chronic Pancreatitis?

(2008) Mark Lazarev et al.   Molecular Pain

Compound Heterozygosity in Sodium Channel Nav1.7 in a Family with Hereditary Erythermalgia

(2008) Mark E Samuels et al.   Molecular Pain

Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk

(2008) A DOEHRING et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction

(2008) Dmitri Proudnikov et al.   NEUROSCIENCE LETTERS

Polymorphisms in the GTP cyclohydrolase gene (GCH1) are associated with ratings of capsaicin pain

(2008) Claudia M. Campbell et al.   PAIN

Genetic mutations that prevent pain: implications for future pain medication

(2008) Bruno Oertel et al.   PHARMACOGENOMICS