Acid-mediated Lipinski’s second rule: application to drug design and targeting in cancer

The role of proton dynamics in the development and maintenance of multidrug resistance in cancer

(2013) Chloë Daniel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Na+-H+ Exchanger, pH Regulation and Cancer

(2013) Stephan J. Reshkin et al.   Recent Patents on Anti-Cancer Drug Discovery

Acid-degradable polymers for drug delivery: a decade of innovation

(2012) Sandra Binauld et al.   CHEMICAL COMMUNICATIONS

Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review

(2011) Paolo E. Porporato et al.   Frontiers in Pharmacology

Metabolic transformation in cancer

(2009) D. A. Tennant et al.   CARCINOGENESIS

Toward a mechanical control of drug delivery. On the relationship between Lipinski’s 2nd rule and cytosolic pH changes in doxorubicin resistance levels in cancer cells: a comparison to published data

(2009) Cyril Rauch   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Multifunctioning pH-responsive nanoparticles from hierarchical self-assembly of polymer brush for cancer drug delivery

(2008) Youqing Shen et al.   AICHE JOURNAL

On the relationship between drug’s size, cell membrane mechanical properties and high levels of multi drug resistance: a comparison to published data

(2008) Cyril Rauch   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Developing a Drug-like Natural Product Library⊥

(2008) Ronald J. Quinn et al.   JOURNAL OF NATURAL PRODUCTS