- Home
- Publications
- Publication Search
- Publication Details
Title
Acid-degradable polymers for drug delivery: a decade of innovation
Authors
Keywords
-
Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 21, Pages 2082
Publisher
Royal Society of Chemistry (RSC)
Online
2012-12-10
DOI
10.1039/c2cc36589h
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Synthesis and Characterization of Acetalated Dextran Polymer and Microparticles with Ethanol as a Degradation Product
- (2012) Kevin J. Kauffman et al. ACS Applied Materials & Interfaces
- Development of a Low Toxicity, Effective pDNA Vector Based on Noncovalent Assembly of Bioresponsive Amino-β-cyclodextrin:Adamantane–Poly(vinyl alcohol)–Poly(ethylene glycol) Transfection Complexes
- (2012) Aditya Kulkarni et al. BIOCONJUGATE CHEMISTRY
- PolyMPC–Doxorubicin Prodrugs
- (2012) Xiangji Chen et al. BIOCONJUGATE CHEMISTRY
- Dual Fluorescent HPMA Copolymers for Passive Tumor Targeting with pH-Sensitive Drug Release: Synthesis and Characterization of Distribution and Tumor Accumulation in Mice by Noninvasive Multispectral Optical Imaging
- (2012) Stefan Hoffmann et al. BIOMACROMOLECULES
- Injectable, Mixed Natural-Synthetic Polymer Hydrogels with Modular Properties
- (2012) Mathew Patenaude et al. BIOMACROMOLECULES
- Hyperbranched Double Hydrophilic Block Copolymer Micelles of Poly(ethylene oxide) and Polyglycerol for pH-Responsive Drug Delivery
- (2012) Sueun Lee et al. BIOMACROMOLECULES
- Immobilization and Intracellular Delivery of an Anticancer Drug Using Mussel-Inspired Polydopamine Capsules
- (2012) Jiwei Cui et al. BIOMACROMOLECULES
- Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging
- (2012) Yuling Xiao et al. BIOMATERIALS
- The degradation and biocompatibility of pH-sensitive biodegradable polyurethanes for intracellular multifunctional antitumor drug delivery
- (2012) Lijuan Zhou et al. BIOMATERIALS
- Polymer conjugates of acridine-type anticancer drugs with pH-controlled activation
- (2012) Ondřej Sedláček et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Recent advances in stimuli-responsive degradable block copolymer micelles: synthesis and controlled drug delivery applications
- (2012) Qian Zhang et al. CHEMICAL COMMUNICATIONS
- Acid Degradable Cross-Linked Micelles for the Delivery of Cisplatin: A Comparison with Nondegradable Cross-Linker
- (2012) Vien T. Huynh et al. CHEMISTRY OF MATERIALS
- Targeting and anti-tumor effect of folic acid-labeled polymer–Doxorubicin conjugates with pH-sensitive hydrazone linker
- (2012) Xiuli Hu et al. JOURNAL OF MATERIALS CHEMISTRY
- Pendant Polymer:Amino-β-Cyclodextrin:siRNA Guest:Host Nanoparticles as Efficient Vectors for Gene Silencing
- (2012) Aditya Kulkarni et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Hydrolytically Degradable Polymer Micelles for Anticancer Drug Delivery to Solid Tumors
- (2012) Petr Chytil et al. MACROMOLECULAR CHEMISTRY AND PHYSICS
- An Extracellular MRI Polymeric Contrast Agent That Degrades at Physiological pH
- (2012) Eric Schopf et al. MOLECULAR PHARMACEUTICS
- Acid-Labile mPEG–Vinyl Ether–1,2-Dioleylglycerol Lipids with Tunable pH Sensitivity: Synthesis and Structural Effects on Hydrolysis Rates, DOPE Liposome Release Performance, and Pharmacokinetics
- (2012) Junhwa Shin et al. MOLECULAR PHARMACEUTICS
- Aerosolized Antimicrobial Agents Based on Degradable Dextran Nanoparticles Loaded with Silver Carbene Complexes
- (2012) Cátia Ornelas-Megiatto et al. MOLECULAR PHARMACEUTICS
- Endocytosis and Intracellular Trafficking as Gateways for Nanomedicine Delivery: Opportunities and Challenges
- (2012) Ruth Duncan et al. MOLECULAR PHARMACEUTICS
- Hyaluronan Oligomers-HPMA Copolymer Conjugates for Targeting Paclitaxel to CD44-Overexpressing Ovarian Carcinoma
- (2012) Gal Journo-Gershfeld et al. PHARMACEUTICAL RESEARCH
- Ketalized poly(amino ester) for stimuli-responsive and biocompatible gene delivery
- (2012) Min Suk Shim et al. Polymer Chemistry
- Synthesis of Monodisperse, Covalently Cross-Linked, Degradable “Smart” Microgels Using Microfluidics
- (2012) Leah R. B. Kesselman et al. Small
- Poly(ethylene glycol)-poly(vinyl alcohol)-adamantanate: synthesis and stimuli-responsive micelle properties
- (2012) Wei Deng et al. Soft Matter
- Injectable, Degradable Thermoresponsive Poly(N-isopropylacrylamide) Hydrogels
- (2012) Mathew Patenaude et al. ACS Macro Letters
- Before and after Endosomal Escape: Roles of Stimuli-Converting siRNA/Polymer Interactions in Determining Gene Silencing Efficiency
- (2011) Young Jik Kwon ACCOUNTS OF CHEMICAL RESEARCH
- Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise
- (2011) Ernst Wagner ACCOUNTS OF CHEMICAL RESEARCH
- Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin
- (2011) Xiao-Bing Xiong et al. ACS Nano
- RGD-Modified PEG-PAMAM-DOX Conjugate: In Vitro and In Vivo Targeting to Both Tumor Neovascular Endothelial Cells and Tumor Cells
- (2011) Saijie Zhu et al. ADVANCED MATERIALS
- Degradable Dextran Particles for Gene Delivery Applications
- (2011) Peter R. Wich et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Acid-Degradable Cationic Dextran Particles for the Delivery of siRNA Therapeutics
- (2011) Jessica L. Cohen et al. BIOCONJUGATE CHEMISTRY
- Degradable Thermoresponsive Nanogels for Protein Encapsulation and Controlled Release
- (2011) Neha Bhuchar et al. BIOCONJUGATE CHEMISTRY
- Endosomal pH-Activatable Poly(ethylene oxide)-graft-Doxorubicin Prodrugs: Synthesis, Drug Release, and Biodistribution in Tumor-Bearing Mice
- (2011) Lei Zhou et al. BIOMACROMOLECULES
- Ketal Cross-Linked Poly(ethylene glycol)-Poly(amino acid)s Copolymer Micelles for Efficient Intracellular Delivery of Doxorubicin
- (2011) Sang Jin Lee et al. BIOMACROMOLECULES
- Detailed characterization of an injectable hyaluronic acid-polyaspartylhydrazide hydrogel for protein delivery
- (2011) Rui Zhang et al. CARBOHYDRATE POLYMERS
- Novel folated and non-folated pullulan bioconjugates for anticancer drug delivery
- (2011) Anna Scomparin et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting
- (2011) Tomáš Etrych et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The use of reversible addition fragmentation chain transfer polymerization for drug delivery systems
- (2011) Andrew Gregory et al. Expert Opinion on Drug Delivery
- Synergistic effect of HPMA copolymer-bound doxorubicin and dexamethasone in vivo on mouse lymphomas
- (2011) Hana Kostková et al. JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
- Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation
- (2011) Elena Martínez-Sanz et al. JOURNAL OF CONTROLLED RELEASE
- Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell
- (2011) Marcelo Calderón et al. JOURNAL OF CONTROLLED RELEASE
- Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy
- (2011) Tomáš Etrych et al. JOURNAL OF CONTROLLED RELEASE
- Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers
- (2011) Claudia Scholz et al. JOURNAL OF CONTROLLED RELEASE
- Dual Stimuli-Responsive Polymeric Micelles Exhibiting “AND” Logic Gate for Controlled Release of Adriamycin
- (2011) Chuan Wei et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Hyperbranched Polyacetals with Tunable Degradation Rates
- (2011) Saptarshi Chatterjee et al. MACROMOLECULES
- Acid Degradable and Biocompatible Polymeric Nanoparticles for the Potential Codelivery of Therapeutic Agents
- (2011) Hien T. T. Duong et al. MACROMOLECULES
- Triggered Release from Polymer Capsules
- (2011) Aaron P. Esser-Kahn et al. MACROMOLECULES
- Synthesis and Characterization of pH-Sensitive Biodegradable Polyurethane for Potential Drug Delivery Applications
- (2011) Lijuan Zhou et al. MACROMOLECULES
- Polymer Micelles with Hydrazone-Ester Dual Linkers for Tunable Release of Dexamethasone
- (2011) Melissa D. Howard et al. PHARMACEUTICAL RESEARCH
- Promoted Transfection Efficiency of pDNA Polyplexes-Loaded Biodegradable Microparticles Containing Acid-Labile Segments and Galactose Grafts
- (2011) Zhu Chen et al. PHARMACEUTICAL RESEARCH
- Block Copolymer Micelles for Controlled Delivery of Glycolytic Enzyme Inhibitors
- (2011) Shanjida Akter et al. PHARMACEUTICAL RESEARCH
- Covalently cross-linked amphiphilic block copolymer micelles
- (2011) Cornelus F. van Nostrum Soft Matter
- Multifunctional Stable and pH-Responsive Polymer Vesicles Formed by Heterofunctional Triblock Copolymer for Targeted Anticancer Drug Delivery and Ultrasensitive MR Imaging
- (2010) Xiaoqiang Yang et al. ACS Nano
- Acetal-Modified Dextran Microparticles with Controlled Degradation Kinetics and Surface Functionality for Gene Delivery in Phagocytic and Non-Phagocytic Cells
- (2010) Joel A. Cohen et al. ADVANCED MATERIALS
- Novel Degradable Polymer Networks Containing Acetal Components and Well-Defined Backbones
- (2010) Xin-Ce Sui et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Comparison of Hydrazone Heterobifunctional Cross-Linking Agents for Reversible Conjugation of Thiol-Containing Chemistry
- (2010) R. James Christie et al. BIOCONJUGATE CHEMISTRY
- Acid-transforming polypeptide micelles for targeted nonviral gene delivery
- (2010) Min Suk Shim et al. BIOMATERIALS
- Degradable, pH-sensitive, membrane-destabilizing, comb-like polymers for intracellular delivery of nucleic acids
- (2010) Yen-Ling Lin et al. BIOMATERIALS
- Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin
- (2010) Marina Talelli et al. BIOMATERIALS
- Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions
- (2010) Dmitri A. Ossipov et al. CHEMICAL COMMUNICATIONS
- Acid-degradable solid-walled microcapsules for pH-responsive burst-release drug delivery
- (2010) Kyle E. Broaders et al. CHEMICAL COMMUNICATIONS
- Dual-response nanocarrier based on graft copolymers with hydrazone bond linkages for improved drug delivery
- (2010) Yueying He et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation
- (2010) Petr Chytil et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Rapid Release of Entrapped Contents from Multi-Functionalizable, Surface Cross-Linked Micelles upon Different Stimulation
- (2010) Shiyong Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Micellar Nanocarriers Assembled from Doxorubicin-Conjugated Amphiphilic Macromolecules (DOX-AM)
- (2010) Leilani S. del Rosario et al. MACROMOLECULAR BIOSCIENCE
- Aqueous Solution Properties of the Acid-Labile Thermoresponsive Poly(meth)acrylamides with Pendent Cyclic Orthoester Groups
- (2010) Fu-Sheng Du et al. MACROMOLECULES
- HPMA Copolymer Conjugates of Paclitaxel and Docetaxel with pH-Controlled Drug Release
- (2010) Tomáš Etrych et al. MOLECULAR PHARMACEUTICS
- HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations
- (2010) Twan Lammers et al. Nanomedicine
- Mixed pH-Sensitive Polymeric Micelles for Combination Drug Delivery
- (2010) Younsoo Bae et al. PHARMACEUTICAL RESEARCH
- PEG-poly(amino acid) Block Copolymer Micelles for Tunable Drug Release
- (2010) Andrei Ponta et al. PHARMACEUTICAL RESEARCH
- Acetals moiety contained pH-sensitive amphiphilic copolymer self-assembly used for drug carrier
- (2010) Jushan Lu et al. POLYMER
- ‘Isothermal’ phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains
- (2010) Felicity Heath et al. Polymer Chemistry
- Polymer−Cisplatin Conjugate Nanoparticles for Acid-Responsive Drug Delivery
- (2009) Santosh Aryal et al. ACS Nano
- A novel thermosensitive polymer with pH-dependent degradation for drug delivery
- (2009) V.K. Garripelli et al. Acta Biomaterialia
- Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers
- (2009) Younsoo Bae et al. ADVANCED DRUG DELIVERY REVIEWS
- Structural and chemical aspects of HPMA copolymers as drug carriers☆
- (2009) Karel Ulbrich et al. ADVANCED DRUG DELIVERY REVIEWS
- Biological Evaluation of Polymeric Micelles with Covalently Bound Doxorubicin
- (2009) David Vetvicka et al. BIOCONJUGATE CHEMISTRY
- Acid-Responsive Linear Polyethylenimine for Efficient, Specific, and Biocompatible siRNA Delivery
- (2009) Min Suk Shim et al. BIOCONJUGATE CHEMISTRY
- pH-Responsive Biodegradable Micelles Based on Acid-Labile Polycarbonate Hydrophobe: Synthesis and Triggered Drug Release
- (2009) Wei Chen et al. BIOMACROMOLECULES
- Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells
- (2009) Lisa A. Gurski et al. BIOMATERIALS
- Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery
- (2009) Mani Prabaharan et al. BIOMATERIALS
- Synthesis and antitumor activity of doxorubicin conjugated stearic acid-g-chitosan oligosaccharide polymeric micelles
- (2009) Fu-Qiang Hu et al. BIOMATERIALS
- Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery
- (2009) Mani Prabaharan et al. BIOMATERIALS
- Injectable in situ cross-linking hydrogels for local antifungal therapy
- (2009) Sarah P. Hudson et al. BIOMATERIALS
- The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin
- (2009) Xiao-Bing Xiong et al. BIOMATERIALS
- Partly PEGylated polyamidoamine dendrimer for tumor-selective targeting of doxorubicin: The effects of PEGylation degree and drug conjugation style
- (2009) Saijie Zhu et al. BIOMATERIALS
- Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel
- (2009) Adam W.G. Alani et al. BIOMATERIALS
- α,α-Trehalose-based polyacetals and macrocyclic acetals
- (2009) Sylwia Kukowka et al. CARBOHYDRATE POLYMERS
- HPMA-based polymer conjugates with drug combination
- (2009) Hana Krakovičová et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micelles
- (2009) Wei Chen et al. JOURNAL OF CONTROLLED RELEASE
- Expansile Nanoparticles: Synthesis, Characterization, andin VivoEfficacy of an Acid-Responsive Polymeric Drug Delivery System
- (2009) Aaron P. Griset et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Acid-Sensitive Polymeric Micelles Based on Thermoresponsive Block Copolymers with Pendent Cyclic Orthoester Groups
- (2009) Xiaonan Huang et al. MACROMOLECULES
- Amphiphilic Copolymer Having Acid-Labile Acetal in the Side Chain as a Hydrophobe: Controlled Release of Aldehyde by Thermoresponsive Aggregation−Dissociation of Polymer Micelles
- (2009) Hisatoyo Morinaga et al. MACROMOLECULES
- Future perspectives and recent advances in stimuli-responsive materials
- (2009) Debashish Roy et al. PROGRESS IN POLYMER SCIENCE
- Enhanced Cell Penetration of Acid-Degradable Particles Functionalized with Cell-Penetrating Peptides
- (2008) Jessica L. Cohen et al. BIOCONJUGATE CHEMISTRY
- Acetal Linked Oligoethylenimines for Use As pH-Sensitive Gene Carriers
- (2008) Veronika Knorr et al. BIOCONJUGATE CHEMISTRY
- Fully Acid-Degradable Biocompatible Polyacetal Microparticles for Drug Delivery
- (2008) Sergey E. Paramonov et al. BIOCONJUGATE CHEMISTRY
- Controlled Delivery of Plasmid DNA and siRNA to Intracellular Targets Using Ketalized Polyethylenimine
- (2008) Min Suk Shim et al. BIOMACROMOLECULES
- One-Pot Conversion of RAFT-Generated Multifunctional Block Copolymers of HPMA to Doxorubicin Conjugated Acid- and Reductant-Sensitive Crosslinked Micelles
- (2008) Zhongfan Jia et al. BIOMACROMOLECULES
- Acid-Labile Core Cross-Linked Micelles for pH-Triggered Release of Antitumor Drugs
- (2008) Yannie Chan et al. BIOMACROMOLECULES
- Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier
- (2008) In Kap Ko et al. BIOMATERIALS
- Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting
- (2008) Tomáš Etrych et al. JOURNAL OF CONTROLLED RELEASE
- Acetal-Derivatized Dextran: An Acid-Responsive Biodegradable Material for Therapeutic Applications
- (2008) Eric M. Bachelder et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Stereochemical Effect ofTrans/CisIsomers on the Aqueous Solution Properties of Acid-Labile Thermoresponsive Polymers
- (2008) Xiaonan Huang et al. MACROMOLECULES
- Poly(N-vinylformamide) Nanogels Capable of pH-Sensitive Protein Release
- (2008) Lianjun Shi et al. MACROMOLECULES
- pH-Responsive Shell Cross-Linked Nanoparticles with Hydrolytically Labile Cross-Links
- (2008) Yali Li et al. MACROMOLECULES
- Acid-Degradable Polyurethane Particles for Protein-Based Vaccines: Biological Evaluation and in Vitro Analysis of Particle Degradation Products
- (2008) Eric M. Bachelder et al. MOLECULAR PHARMACEUTICS
- Recent Developments in Cyclic Acetal Biomaterials for Tissue Engineering Applications
- (2008) Erin E. Falco et al. PHARMACEUTICAL RESEARCH
- An Acid Sensitive Ketal-Based Polyethylene Glycol-Oligoethylenimine Copolymer Mediates Improved Transfection Efficiency at Reduced Toxicity
- (2008) Veronika Knorr et al. PHARMACEUTICAL RESEARCH
- pH-Responsive polymers: synthesis, properties and applications
- (2008) Sheng Dai et al. Soft Matter
- pH-Triggered Reversible “Stealth” Polycationic Micelles
- (2007) Jingxia Gu et al. BIOMACROMOLECULES
- Prodrug Strategies in Anticancer Chemotherapy
- (2007) Felix Kratz et al. ChemMedChem
- Acid-Degradable Core-Crosslinked Micelles Prepared from Thermosensitive Glycopolymers Synthesized via RAFT Polymerization
- (2007) Ling Zhang et al. MACROMOLECULAR RAPID COMMUNICATIONS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started