A Repurposing Approach Identifies Off-Patent Drugs with Fungicidal Cryptococcal Activity, a Common Structural Chemotype, and Pharmacological Properties Relevant to the Treatment of Cryptococcosis
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Repurposing Approach Identifies Off-Patent Drugs with Fungicidal Cryptococcal Activity, a Common Structural Chemotype, and Pharmacological Properties Relevant to the Treatment of Cryptococcosis
Authors
Keywords
-
Journal
EUKARYOTIC CELL
Volume 12, Issue 2, Pages 278-287
Publisher
American Society for Microbiology
Online
2012-12-16
DOI
10.1128/ec.00314-12
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Antidepressant Sertraline Provides a Promising Therapeutic Option for Neurotropic Cryptococcal Infections
- (2012) Bing Zhai et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The Triple Threat of Cryptococcosis: It's the Body Site, the Strain, and/or the Host
- (2012) J. R. Perfect mBio
- Antifungal Drug Discovery: Something Old and Something New
- (2012) Arielle Butts et al. PLoS Pathogens
- Thermal Denaturation Assays in Chemical Biology
- (2011) Guillermo Senisterra et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Recent progress in biological activities of synthesized phenothiazines
- (2011) Krystian Pluta et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine
- (2011) E. Abbate et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole
- (2011) M. Spitzer et al. Molecular Systems Biology
- Mechanism of the Synergistic Effect of Amiodarone and Fluconazole in Candida albicans
- (2010) S. Gamarra et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America
- (2010) John R. Perfect et al. CLINICAL INFECTIOUS DISEASES
- Cryptococcal Interactions with the Host Immune System
- (2010) Kerstin Voelz et al. EUKARYOTIC CELL
- Polymyxin B, in combination with fluconazole, exerts a potent fungicidal effect
- (2010) B. Zhai et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- A high-throughput assay of yeast cell lysis for drug discovery and genetic analysis
- (2010) Louis DiDone et al. Nature Protocols
- A high content screening assay for identifying lysosomotropic compounds
- (2010) Sashi Nadanaciva et al. TOXICOLOGY IN VITRO
- Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
- (2009) Benjamin J Park et al. AIDS
- Antifungal Activity of Tamoxifen: In Vitro and In Vivo Activities and Mechanistic Characterization
- (2009) K. Dolan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Characteristics of compounds that cross the blood-brain barrier
- (2009) William A Banks BMC Neurology
- Independent Association between Rate of Clearance of Infection and Clinical Outcome of HIV‐Associated Cryptococcal Meningitis: Analysis of a Combined Cohort of 262 Patients
- (2009) Tihana Bicanic et al. CLINICAL INFECTIOUS DISEASES
- Treatment of cryptococcal meningitis in resource limited settings
- (2009) Derek J Sloan et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Dronedarone and amiodarone—the safety versus efficacy debate
- (2009) Eric N. Prystowsky Nature Reviews Cardiology
- Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling
- (2009) Aruna D. Balgi et al. PLoS One
- Fungicidal activity of amiodarone is tightly coupled to calcium influx
- (2008) Sabina Muend et al. FEMS YEAST RESEARCH
- Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast
- (2008) Elke Ericson et al. PLoS Genetics
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started