A Repurposing Approach Identifies Off-Patent Drugs with Fungicidal Cryptococcal Activity, a Common Structural Chemotype, and Pharmacological Properties Relevant to the Treatment of Cryptococcosis

The Antidepressant Sertraline Provides a Promising Therapeutic Option for Neurotropic Cryptococcal Infections

(2012) Bing Zhai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Triple Threat of Cryptococcosis: It's the Body Site, the Strain, and/or the Host

(2012) J. R. Perfect   mBio

Antifungal Drug Discovery: Something Old and Something New

(2012) Arielle Butts et al.   PLoS Pathogens

Thermal Denaturation Assays in Chemical Biology

(2011) Guillermo Senisterra et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Recent progress in biological activities of synthesized phenothiazines

(2011) Krystian Pluta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine

(2011) E. Abbate et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole

(2011) M. Spitzer et al.   Molecular Systems Biology

Mechanism of the Synergistic Effect of Amiodarone and Fluconazole in Candida albicans

(2010) S. Gamarra et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America

(2010) John R. Perfect et al.   CLINICAL INFECTIOUS DISEASES

Cryptococcal Interactions with the Host Immune System

(2010) Kerstin Voelz et al.   EUKARYOTIC CELL

Polymyxin B, in combination with fluconazole, exerts a potent fungicidal effect

(2010) B. Zhai et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A high-throughput assay of yeast cell lysis for drug discovery and genetic analysis

(2010) Louis DiDone et al.   Nature Protocols

A high content screening assay for identifying lysosomotropic compounds

(2010) Sashi Nadanaciva et al.   TOXICOLOGY IN VITRO

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Antifungal Activity of Tamoxifen: In Vitro and In Vivo Activities and Mechanistic Characterization

(2009) K. Dolan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characteristics of compounds that cross the blood-brain barrier

(2009) William A Banks   BMC Neurology

Independent Association between Rate of Clearance of Infection and Clinical Outcome of HIV‐Associated Cryptococcal Meningitis: Analysis of a Combined Cohort of 262 Patients

(2009) Tihana Bicanic et al.   CLINICAL INFECTIOUS DISEASES

Treatment of cryptococcal meningitis in resource limited settings

(2009) Derek J Sloan et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Dronedarone and amiodarone—the safety versus efficacy debate

(2009) Eric N. Prystowsky   Nature Reviews Cardiology

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

Fungicidal activity of amiodarone is tightly coupled to calcium influx

(2008) Sabina Muend et al.   FEMS YEAST RESEARCH

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

(2008) Elke Ericson et al.   PLoS Genetics