The Hippo pathway: key interaction and catalytic domains in organ growth control, stem cell self-renewal and tissue regeneration

Structural Features and Ligand Binding Properties of Tandem WW Domains from YAP and TAZ, Nuclear Effectors of the Hippo Pathway

(2011) Claire Webb et al.   BIOCHEMISTRY

Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

(2011) Z. Salah et al.   CANCER RESEARCH

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

MOB control: Reviewing a conserved family of kinase regulators

(2011) Alexander Hergovich   CELLULAR SIGNALLING

Hippo signaling inDrosophila: Recent advances and insights

(2011) Binnaz Kucuk Staley et al.   DEVELOPMENTAL DYNAMICS

Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit

(2011) B. N. Nicolay et al.   GENES & DEVELOPMENT

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

(2011) E. Aragon et al.   GENES & DEVELOPMENT

A kinase shRNA screen links LATS2 and the pRB tumor suppressor

(2011) K. Tschop et al.   GENES & DEVELOPMENT

Mammalian Hippo pathway: from development to cancer and beyond

(2011) Y. Bao et al.   JOURNAL OF BIOCHEMISTRY

Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

(2011) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

Integrating developmental signals: a Hippo in the (path)way

(2011) A Mauviel et al.   ONCOGENE

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components

(2011) N.-G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Coordinating developmental signaling: novel roles for the Hippo pathway

(2011) Xaralabos Varelas et al.   TRENDS IN CELL BIOLOGY

WW domain interactions regulate the Hippo tumor suppressor pathway

(2011) Z Salah et al.   Cell Death & Disease

Structural and functional insights into the TEAD-YAP complex in the Hippo signaling pathway

(2011) Liming Chen et al.   Protein & Cell

Structure of a 14-3-3σ–YAP phosphopeptide complex at 1.15 Å resolution

(2010) Benjamin Schumacher et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

(2010) Tsutomu Oka et al.   BIOCHEMICAL JOURNAL

PDZ domains and their binding partners: structure, specificity, and modification

(2010) Ho-Jin Lee et al.   Cell Communication and Signaling

Influence of Fat-Hippo and Notch signaling on the proliferation and differentiation of Drosophila optic neuroepithelia

(2010) B. V. V. G. Reddy et al.   DEVELOPMENT

The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

(2010) P. Karpowicz et al.   DEVELOPMENT

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner

(2010) Eline Remue et al.   FEBS LETTERS

Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway

(2010) Linda M Parsons et al.   FLY

Structural basis of YAP recognition by TEAD4 in the Hippo pathway

(2010) L. Chen et al.   GENES & DEVELOPMENT

Structural insights into the YAP and TEAD complex

(2010) Z. Li et al.   GENES & DEVELOPMENT

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

When pathways collide: collaboration and connivance among signalling proteins in development

(2010) Helen McNeill et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and functional analysis of the YAP-binding domain of human TEAD2

(2010) W. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

(2010) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

(2010) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis

(2010) K.-P. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modularity in the Hippo signaling pathway

(2010) Marius Sudol et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

The FERM-Domain Protein Expanded Regulates Hippo Pathway Activity via Direct Interactions with the Transcriptional Activator Yorkie

(2009) Caroline Badouel et al.   DEVELOPMENTAL CELL

Regulation of organ size: Insights from theDrosophilaHippo signaling pathway

(2009) Madhuri Kango-Singh et al.   DEVELOPMENTAL DYNAMICS

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

(2009) A. Fernandez-L et al.   GENES & DEVELOPMENT

Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif

(2009) Tsutomu Oka et al.   GENES TO CELLS

Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120

(2009) Zengqiang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

(2009) Jianmin Zhang et al.   NATURE CELL BIOLOGY

Mst1-FoxO Signaling Protects Naïve T Lymphocytes from Cellular Oxidative Stress in Mice

(2009) Juhyun Choi et al.   PLoS One

Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the Drosophila Hippo Pathway

(2008) J. Zhang et al.   CANCER RESEARCH

TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

(2008) Q.-Y. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY