Dynamics of telomeric chromatin at the crossroads of aging and cancer

The telomere story or the triumph of an open-minded research

(2010) Eric Gilson et al.   BIOCHIMIE

Role of TRF2 in the assembly of telomeric chromatin

(2010) Roberta Benetti et al.   CELL CYCLE

Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2

(2009) Paolo Spallarossa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Shelterin Protein TRF2 Inhibits Chk2 Activity at Telomeres in the Absence of DNA Damage

(2009) Giacomo Buscemi et al.   CURRENT BIOLOGY

Genetic dissection of the mechanisms underlying telomere-associated diseases: impact of the TRF2 telomeric protein on mouse epidermal stem cells

(2009) G. J. Stout et al.   Disease Models & Mechanisms

TRF2 promotes, remodels and protects telomeric Holliday junctions

(2009) Anaïs Poulet et al.   EMBO JOURNAL

Control of telomere length by a trimming mechanism that involves generation of t-circles

(2009) Hilda A Pickett et al.   EMBO JOURNAL

Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN

(2009) N. Arnoult et al.   GENES & DEVELOPMENT

The CST Complex and Telomere Maintenance: The Exception Becomes the Rule

(2009) Raymund J. Wellinger   MOLECULAR CELL

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

(2009) Yoshiko Maida et al.   NATURE

The effect of the TRF2 N-terminal and TRFH regions on telomeric G-quadruplex structures

(2009) Ilene M. Pedroso et al.   NUCLEIC ACIDS RESEARCH

The Myb/SANT domain of the telomere-binding protein TRF2 alters chromatin structure

(2009) Asmaa M. Baker et al.   NUCLEIC ACIDS RESEARCH

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

(2009) Angela Rizzo et al.   NUCLEIC ACIDS RESEARCH

Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination

(2009) I. Draskovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

Leukocyte Telomere Dynamics: Longitudinal Findings Among Young Adults in the Bogalusa Heart Study

(2008) A. Aviv et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

G-Quadruplex Ligand RHPS4 Potentiates the Antitumor Activity of Camptothecins in Preclinical Models of Solid Tumors

(2008) C. Leonetti et al.   CLINICAL CANCER RESEARCH

Nontelomeric TRF2-REST Interaction Modulates Neuronal Gene Silencing and Fate of Tumor and Stem Cells

(2008) Peisu Zhang et al.   CURRENT BIOLOGY

Distinct Functions of POT1 at Telomeres

(2008) K. S. Barrientos et al.   MOLECULAR AND CELLULAR BIOLOGY

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

(2008) H. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins

(2008) Y. Chen et al.   SCIENCE

The telosome/shelterin complex and its functions

(2008) Huawei Xin et al.   GENOME BIOLOGY

Targeting telomeres and telomerase

(2007) Anne De Cian et al.   BIOCHIMIE