Tetrandrine induces apoptosis Via caspase-8, -9, and -3 and poly (ADP ribose) polymerase dependent pathways and autophagy through beclin-1/ LC3-I, II signaling pathways in human oral cancer HSC-3 cells

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

GSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition

(2013) E Gavilán et al.   Cell Death & Disease

DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions

(2012) Muktheshwar Gandesiri et al.   APOPTOSIS

Genetic polymorphism of drug metabolizing enzymes (GSTM1 and CYP1A1) as risk factors for oral premalignant lesions and oral cancer

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Oral cancer in Taiwan: is diabetes a risk factor?

(2012) Chin-Hsiao Tseng   Clinical Oral Investigations

Autophagy-related Gene 7 (ATG7) and Reactive Oxygen Species/Extracellular Signal-regulated Kinase Regulate Tetrandrine-induced Autophagy in Human Hepatocellular Carcinoma

(2012) Ke Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding

(2011) Elaine A. Dunlop et al.   Autophagy

Combination of Tetrandrine with cisplatin enhances cytotoxicity through growth suppression and apoptosis in ovarian cancer in vitro and in vivo

(2011) Yuxing Zhang et al.   CANCER LETTERS

Fangchinoline Inhibits Breast Adenocarcinoma Proliferation by Inducing Apoptosis

(2011) Zhi-Bo Xing et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation

(2011) Chuan-Ming Xie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetics/epigenetics of oral premalignancy: current status and future research*

(2011) MW Lingen et al.   ORAL DISEASES

Possible association between nickel and chromium and oral cancer: A case–control study in central Taiwan

(2011) Tzu-Hsuen Yuan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Involvement of PI3K/AKT/GSK3ß pathway in tetrandrine-induced G1 arrest and apoptosis

(2010) Xuan Li Chen et al.   CANCER BIOLOGY & THERAPY

GSK-3β is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity

(2010) James A McCubrey et al.   CANCER BIOLOGY & THERAPY

Danthron, an Anthraquinone Derivative, Induces DNA Damage and Caspase Cascades-Mediated Apoptosis in SNU-1 Human Gastric Cancer Cells through Mitochondrial Permeability Transition Pores and Bax-Triggered Pathways

(2010) Jo-Hua Chiang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma

(2010) Chaoyang Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Chronic exposure to heavy metals and risk of oral cancer in Taiwanese males

(2010) Che-Chun Su et al.   ORAL ONCOLOGY

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation

(2009) Elsa-Noah N’Diaye et al.   Autophagy

Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice

(2009) Jiann-Ming Wu et al.   CANCER LETTERS

Macroautophagy and its role in nutrient homeostasis

(2009) Martha H Stipanuk   NUTRITION REVIEWS

Tetrandrine suppresses tumor growth and angiogenesis of gliomas in rats

(2008) Yun Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Oral cancer and genetic polymorphism of DNA double strand break gene Ku70 in Taiwan

(2008) Da-Tian Bau et al.   ORAL ONCOLOGY

Cell death and autophagy: Cytokines, drugs, and nutritional factors

(2008) Wilfried Bursch et al.   TOXICOLOGY