The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description

Fronto-striatal circuits in response-inhibition: Relevance to addiction

(2015) Sharon Morein-Zamir et al.   BRAIN RESEARCH

The Platform Trial

(2015) Scott M. Berry et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

In Vivo Imaging of Cerebral Dopamine D3 Receptors in Alcoholism

(2014) David Erritzoe et al.   NEUROPSYCHOPHARMACOLOGY

DRD3 variation associates with early-onset heroin dependence, but not specific personality traits

(2014) Shin-Chang Kuo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inhibition and the right inferior frontal cortex: one decade on

(2014) Adam R. Aron et al.   TRENDS IN COGNITIVE SCIENCES

Dopamine ups and downs in vulnerability to addictions: a neurodevelopmental model

(2014) Marco Leyton et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Abstinence duration modulates striatal functioning during monetary reward processing in cocaine patients

(2013) Juan-Carlos Bustamante et al.   ADDICTION BIOLOGY

A neurocognitive approach to understanding the neurobiology of addiction

(2013) Xavier Noël et al.   CURRENT OPINION IN NEUROBIOLOGY

Acute NK1 receptor antagonist administration affects reward incentive anticipation processing in healthy volunteers

(2013) Kanako Saji et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

The NK1 Receptor Antagonist L822429 Reduces Heroin Reinforcement

(2013) Estelle Barbier et al.   NEUROPSYCHOPHARMACOLOGY

The Role of the Neurokinin-1 Receptor in Stress-Induced Reinstatement of Alcohol and Cocaine Seeking

(2013) Jesse R Schank et al.   NEUROPSYCHOPHARMACOLOGY

Heightened D3 Dopamine Receptor Levels in Cocaine Dependence and Contributions to the Addiction Behavioral Phenotype: A Positron Emission Tomography Study with [11C]-(+)-PHNO

(2013) Doris E Payer et al.   NEUROPSYCHOPHARMACOLOGY

Processing of primary and secondary rewards: A quantitative meta-analysis and review of human functional neuroimaging studies

(2013) Guillaume Sescousse et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Behavioral and neuroimaging evidence for overreliance on habit learning in alcohol-dependent patients

(2013) Z Sjoerds et al.   Translational Psychiatry

Effect of the dopamine D3 receptor antagonist GSK598809 on brain responses to rewarding food images in overweight and obese binge eaters

(2012) Chris M. Dodds et al.   APPETITE

The D2/3dopamine receptor in pathological gambling: a positron emission tomography study with [11C]-(+)-propyl-hexahydro-naphtho-oxazin and [11C]raclopride

(2012) Isabelle Boileau et al.   ADDICTION

Improvement of Brain Reward Abnormalities by Antipsychotic Monotherapy in Schizophrenia

(2012) Mette Odegaard Nielsen et al.   ARCHIVES OF GENERAL PSYCHIATRY

Effect of dopamine D3 receptor antagonism on approach responses to food cues in overweight and obese individuals

(2012) Karin Mogg et al.   BEHAVIOURAL PHARMACOLOGY

Distinctive Personality Traits and Neural Correlates Associated with Stimulant Drug Use Versus Familial Risk of Stimulant Dependence

(2012) Karen D. Ersche et al.   BIOLOGICAL PSYCHIATRY

Dopaminergic dysfunction in abstinent dexamphetamine users: Results from a pharmacological fMRI study using a reward anticipation task and a methylphenidate challenge

(2012) M.L.J. Schouw et al.   DRUG AND ALCOHOL DEPENDENCE

Pharmacokinetics and central nervous system effects of the novel dopamine D3 receptor antagonist GSK598809 and intravenous alcohol infusion at pseudo-steady state

(2012) ET te Beek et al.   JOURNAL OF PSYCHOPHARMACOLOGY

BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP

(2012) AR Lingford-Hughes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Occupancy of Brain Dopamine D3 Receptors and Drug Craving: A Translational Approach

(2012) Manolo Mugnaini et al.   NEUROPSYCHOPHARMACOLOGY

Have we been asking the right questions when assessing response inhibition in go/no-go tasks with fMRI? A meta-analysis and critical review

(2012) Marion Criaud et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Abnormal Brain Structure Implicated in Stimulant Drug Addiction

(2012) K. D. Ersche et al.   SCIENCE

Dopaminergic genes modulate response inhibition in alcohol abusing adults

(2011) Francesca M. Filbey et al.   ADDICTION BIOLOGY

An Initial Study of Neural Responses to Monetary Incentives as Related to Treatment Outcome in Cocaine Dependence

(2011) Zhiru Jia et al.   BIOLOGICAL PSYCHIATRY

Response Perseveration in Stimulant Dependence Is Associated with Striatal Dysfunction and Can Be Ameliorated by a D2/3 Receptor Agonist

(2011) Karen D. Ersche et al.   BIOLOGICAL PSYCHIATRY

The Neural Basis of Drug Stimulus Processing and Craving: An Activation Likelihood Estimation Meta-Analysis

(2011) Henry W. Chase et al.   BIOLOGICAL PSYCHIATRY

The neurobiology of cognitive control in successful cocaine abstinence

(2011) Colm G. Connolly et al.   DRUG AND ALCOHOL DEPENDENCE

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

(2011) Rita Z. Goldstein et al.   NATURE REVIEWS NEUROSCIENCE

Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429

(2011) Jesse R. Schank et al.   PSYCHOPHARMACOLOGY

Altered neural response of the appetitive emotional system in cocaine addiction: an fMRI Study

(2010) Samuel Asensio et al.   ADDICTION BIOLOGY

Limited Associations of Dopamine System Genes With Alcohol Dependence and Related Traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD)

(2010) Laura M. Hack et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Influence of Compulsivity of Drug Abuse on Dopaminergic Modulation of Attentional Bias in Stimulant Dependence

(2010) Karen D. Ersche et al.   ARCHIVES OF GENERAL PSYCHIATRY

Drug Addiction Endophenotypes: Impulsive Versus Sensation-Seeking Personality Traits

(2010) Karen D. Ersche et al.   BIOLOGICAL PSYCHIATRY

Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11C]PHNO, and a Selective D3 Receptor Antagonist

(2010) Graham Searle et al.   BIOLOGICAL PSYCHIATRY

A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial

(2010) Sanjay J. Mathew et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A genetic determinant of the striatal dopamine response to alcohol in men

(2010) V A Ramchandani et al.   MOLECULAR PSYCHIATRY

The role of the right inferior frontal gyrus: inhibition and attentional control

(2010) Adam Hampshire et al.   NEUROIMAGE

Individual differences in prefrontal cortex function and the transition from drug use to drug dependence

(2010) Olivier George et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Working memory fMRI activation in cocaine-dependent subjects: Association with treatment response

(2010) F. Gerard Moeller et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Peripheral biomarkers of cognitive response to dopamine receptor agonist treatment

(2010) Karen D. Ersche et al.   PSYCHOPHARMACOLOGY

Substance P in Stress and Anxiety

(2009) Karl Ebner et al.   Annals of the New York Academy of Sciences

Reward Processing After Catecholamine Depletion in Unmedicated, Remitted Subjects with Major Depressive Disorder

(2009) Gregor Hasler et al.   BIOLOGICAL PSYCHIATRY

Ventral Striatal Activation During Reward Anticipation Correlates with Impulsivity in Alcoholics

(2009) Anne Beck et al.   BIOLOGICAL PSYCHIATRY

Neuronal pathways linking substance P to drug addiction and stress

(2009) K.G. Commons   BRAIN RESEARCH

Tachykinin Receptors as Therapeutic Targets in Stress-Related Disorders

(2009) Karl Ebner et al.   CURRENT PHARMACEUTICAL DESIGN

Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [11C]diprenorphine PET study

(2009) Tim M. Williams et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers

(2009) Ciara McCabe et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Striatal Dopamine D2/D3 Receptor Availability Is Reduced in Methamphetamine Dependence and Is Linked to Impulsivity

(2009) B. Lee et al.   JOURNAL OF NEUROSCIENCE

Reconciling the Role of Serotonin in Behavioral Inhibition and Aversion: Acute Tryptophan Depletion Abolishes Punishment-Induced Inhibition in Humans

(2009) M. J. Crockett et al.   JOURNAL OF NEUROSCIENCE

Imaging advances in developing new medications for addiction

(2009) Frederick Gerard Moeller et al.   NEUROPSYCHOPHARMACOLOGY

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

The Reward Circuit: Linking Primate Anatomy and Human Imaging

(2009) Suzanne N Haber et al.   NEUROPSYCHOPHARMACOLOGY

Translating the neuroscience of alcoholism into clinical treatments: From blocking the buzz to curing the blues

(2009) Markus Heilig et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Drug Abuse: Vulnerability and Transition to Addiction

(2009) M. Le Moal   PHARMACOPSYCHIATRY

Reward Processing by the Opioid System in the Brain

(2009) Julie Le Merrer et al.   PHYSIOLOGICAL REVIEWS

Mu and Delta Opioid Receptors Oppositely Regulate Motor Impulsivity in the Signaled Nose Poke Task

(2009) Mary C. Olmstead et al.   PLoS One

Cocaine craving and use during daily life

(2009) Kenzie L. Preston et al.   PSYCHOPHARMACOLOGY

Acute effects of morphine on distinct forms of impulsive behavior in rats

(2009) Tommy Pattij et al.   PSYCHOPHARMACOLOGY

Impulsivity and response inhibition in alcohol dependence and problem gambling

(2009) Andrew J. Lawrence et al.   PSYCHOPHARMACOLOGY

Modulation of brain response to emotional images by alcohol cues in alcohol-dependent patients

(2008) Jodi M. Gilman et al.   ADDICTION BIOLOGY

Effect of Naltrexone and Ondansetron on Alcohol Cue–Induced Activation of the Ventral Striatum in Alcohol-Dependent People

(2008) Hugh Myrick et al.   ARCHIVES OF GENERAL PSYCHIATRY

An Evaluation of μ-Opioid Receptor (OPRM1) as a Predictor of Naltrexone Response in the Treatment of Alcohol Dependence

(2008) Raymond F. Anton et al.   ARCHIVES OF GENERAL PSYCHIATRY

Pretreatment Brain Activation During Stroop Task Is Associated with Outcomes in Cocaine-Dependent Patients

(2008) Judson A. Brewer et al.   BIOLOGICAL PSYCHIATRY

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Enhanced Negative Emotion and Alcohol Craving and Altered Physiological Responses Following Stress and Cue Exposure in Alcohol Dependent Individuals

(2008) Rajita Sinha et al.   NEUROPSYCHOPHARMACOLOGY

Impulsivity as a vulnerability marker for substance-use disorders: Review of findings from high-risk research, problem gamblers and genetic association studies

(2008) Antonio Verdejo-García et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dysregulation of emotional response in current and abstinent heroin users: negative heightening and positive blunting

(2008) Francisco Aguilar de Arcos et al.   PSYCHOPHARMACOLOGY

Neurokinin 1 Receptor Antagonism as a Possible Therapy for Alcoholism

(2008) D. T. George et al.   SCIENCE

Meta-analysis of Go/No-go tasks demonstrating that fMRI activation associated with response inhibition is task-dependent

(2007) Daniel J. Simmonds et al.   NEUROPSYCHOLOGIA

Inhibitory control and emotional stress regulation: Neuroimaging evidence for frontal–limbic dysfunction in psycho-stimulant addiction

(2007) Chiang-shan Ray Li et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS