Pig-agene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3-propane sultone

Effective use of the Pig-a gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals

(2012) Takafumi Kimoto et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Efficient Monitoring of In Vivo Pig-a Gene Mutation and Chromosomal Damage: Summary of 7 Published Studies and Results From 11 New Reference Compounds

(2012) Stephen D. Dertinger et al.   TOXICOLOGICAL SCIENCES

Can carcinogenic potency be predicted from in vivo genotoxicity data? a meta-analysis of historical data

(2011) Lya G. Hernández et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Manifestation and persistence of Pig-a mutant red blood cells in C57BL/6 mice following single and split doses of N-ethyl-N-nitrosourea

(2011) Javed A. Bhalli et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories

(2011) Stephen D. Dertinger et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

When pigs fly: Immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis

(2011) Stephen D. Dertinger et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment

(2010) Vasily N. Dobrovolsky et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing

(2010) Andreas Rothfuss et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Integration of Mutation and Chromosomal Damage Endpoints into 28-Day Repeat Dose Toxicology Studies

(2010) Stephen D. Dertinger et al.   TOXICOLOGICAL SCIENCES

Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea

(2009) Daishiro Miura et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop

(2009) Stefan Pfuhler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens

(2009) Souk Phonethepswath et al.   TOXICOLOGICAL SCIENCES

In vivo mutation assay based on the endogenousPig-a locus

(2008) Steven M. Bryce et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Development of an in vivo gene mutation assay using the endogenousPig-Agene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat

(2008) Daishiro Miura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Analysis of in vivo mutation data can inform cancer risk assessment

(2008) Martha M. Moore et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY