Integration of Mutation and Chromosomal Damage Endpoints into 28-Day Repeat Dose Toxicology Studies

Accumulation and persistence of Pig-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea

(2009) Daishiro Miura et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop

(2009) Stefan Pfuhler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens

(2009) Souk Phonethepswath et al.   TOXICOLOGICAL SCIENCES

Development of an in vivo gene mutation assay using the endogenousPig-Agene: II. Selection ofPig-Amutant rat spleen T-cells with proaerolysin and sequencingPig-AcDNA from the mutants

(2008) Daishiro Miura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

In vivo mutation assay based on the endogenousPig-a locus

(2008) Steven M. Bryce et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Development of an in vivo gene mutation assay using the endogenousPig-Agene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat

(2008) Daishiro Miura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Regulatory aspects of genotoxicity testing: from hazard identification to risk assessment

(2008) D. Blakey et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Erythrocyte-based Pig-a gene mutation assay: Demonstration of cross-species potential

(2008) Souk Phonethepswath et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS