Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Rab5 Proteins Regulate Activation and Localization of Target of Rapamycin Complex 1

(2012) Dave Bridges et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes

(2012) Andrea Longatti et al.   JOURNAL OF CELL BIOLOGY

Glutaminolysis Activates Rag-mTORC1 Signaling

(2012) Raúl V. Durán et al.   MOLECULAR CELL

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation

(2011) Takashi Itoh et al.   JOURNAL OF CELL BIOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor

(2011) Takahide Matsui et al.   TRAFFIC

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Regulation of mTORC1 by the Rab and Arf GTPases

(2010) Li Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLC36A4 (hPAT4) Is a High Affinity Amino Acid Transporter When Expressed inXenopus laevisOocytes

(2010) Samyuktha Muralidharan Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation

(2010) S Heublein et al.   ONCOGENE

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

(2009) Yu-Yun Chang et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TOR1 and TOR2 Have Distinct Locations in Live Cells

(2008) Thomas W. Sturgill et al.   EUKARYOTIC CELL

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

(2008) Takashi Itoh et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE